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The map label for this gene is mngB [H]

Identifier: 94994822

GI number: 94994822

Start: 1353687

End: 1356392

Strand: Direct

Name: mngB [H]

Synonym: MGAS10750_Spy1426

Alternate gene names: 94994822

Gene position: 1353687-1356392 (Clockwise)

Preceding gene: 94994821

Following gene: 94994825

Centisome position: 69.88

GC content: 44.27

Gene sequence:

>2706_bases
ATGGCAACTAAAAAAGTACATATTATTTCACACAGTCACTGGGATCGCGAGTGGTACATGGCTTACGAACAACACCACAT
GCGTCTGATTAACTTAATAGATGACCTGTTAGAAGTTTTTCAAACGGATCCTGATTTTCATAGTTTTCATTTGGATGGGC
AAACCATTATCCTAGATGATTATTTGCAAGTACGCCCCGAACGAGAACCTGAGATTAGACAAGCCATTGCTTCGGGAAAA
CTCCGTATCGGACCTTTCTATATCTTACAGGACGATTTTTTGACCAGCAGTGAATCCAATGTGCGCAATATGCTGATTGG
TAAGGAAGATTGTGACAGATGGGGCGCTAGTGTGCCACTTGGTTATTTTCCTGATACCTTTGGAAATATGGGACAAACAC
CACAGCTGATGTTAAAAGCCGGCCTACAAGCTGCTGCCTTTGGTCGTGGCATTCGTCCAACTGGATTTAACAATCAAGTA
GATACCAGTGAAAAATACAGCTCACAATTCTCTGAAATCAGTTGGCAAGGCCCAGATAACAGTCGTATTCTTGGACTCCT
CTTCGCCAACTGGTACAGCAATGGCAATGAGATCCCGACAACAGAAGCTGAGGCGCGTCTTTTTTGGGATAAAAAACTTG
CTGACGCTGAACGCTTTGCCTCAACCAAGCACCTTCTGATGATGAACGGGTGTGATCATCAACCCGTACAACTTGATGTC
ACCAAGGCAATCGCCTTAGCCAACCAACTCTATCCTGATTACGAATTTGTGCATTCCTGCTTTGAAGATTACTTGTCTGA
TCTCGCAAATGATTTACCAGATAACCTTTCAACCGTCCAAGGAGAGATTACCAGTCAAGAGACAGATGGCTGGTATACCC
TAGCTAACACGGCTTCTGCTCGCATTTACCTCAAACAGGCTAATACCAGAGTCTCTCGTCAACTCGAAAACATCACCGAA
CCCTTAGCAGCAATGGCTTATGAGGTGACAAGTACCTACCCTCACGACCAACTGCGTTACGCTTGGAAAACCCTCACGCA
AAATCACCCTCATGATTCTATCTGTGGTTGTAGTGTTGATAGTGTTCATCGGGAAATGATGAACCGTTTTGAAAAAGCCT
ATGAAGTCGGACACTATTTAGCAAAAGAAGCTGCCCAGCAAATTGCTGGCGCAGTTAACACGAGTGACTTTCCAACAGAT
AGCCAACCTTTCCTCTTATTTAATACCAGTGGCCATTCCAAAACAAGTGTTACTGAGCTCACCCTGACCTGGAAAAAATA
TTATTTTGGCCAACGCTTTCCTAAAGAGGTTTACCAAGAAGCTCAAGAGTATTTGGCAGGACTCTCCCAATCTTTCCAAG
TCATTGATGTATCAGGAAACACTATCTCAGAAGCAGACATTTTGGACACAAGCATCGCCTTTGACTACGATTTGCCCAAG
AGAACCTTCCGAGAACCTTATTTCGCCATCAAAGTGAGATTACGGCTACCAATAACTCTCCCTGCCATGTCTTGGAAAGC
CTTAGCATTACAACTAGGAAACGAGACAGCTCCTTCAGCAACGGTCCCACTCTACGACGATAGTAATCAGTGCCTTGAAA
ATGAGTTTCTAAAAGTTATGATACAAACCGATGGCCGTCTAACCATCACCGATAAACAGTCAGGGGTGAGCTATCAAGAT
CTCCTACGGTTTGAAGATTGTGGCGATATTGGAAATGAATACATTTCCCGCCAACCAACTCATGACCAACCTTTCTATGC
GGACCAAGGGACCACCAAGCTTAACATCATTAGCAACACCGCTCAAGTTGCTGAACTTGAAATCCAGCAAACCTTTGCCA
TTCCTATCTCCGCAGATAAGCTCTTACAGGCTGAGATGGAAGCTGTCATTGACATCACAGAACGCCAAGCAAGACGTTCA
CAAGAAAAGGCTGAGCTAACCTTAACAACCCTTATCCGCATGGAGAAAAACAATCCTCGCCTCCAATTCACCACAAGTTT
TGATAACCAAATGACTAATCATCGCTTGCGCGTCCTATTCCCAACGCACCTTAAAACAGACCATCATCTAGCTGACAGTA
TTTTTGAAACTGTCAAACGTCCAAATCATCCAGATGCCACCTTTTGGAAGAATCCAAGTAACCCACAGCACCAAGAATGC
TTTGTGAGTCTCTTTGATGGTGAAAATGGAGTCACTATTGGTAACTATGGCCTCAACGAATATGAGATCTTACCAGATAC
CAACACCATTGCCATCACTCTCTTACGTTCTGTTGGTGAAATGGGCGACTGGGGGTATTTCCCTACTCCTGAAGCCCAAT
GCCTCGGCAAACACAGCCTATCTTATAGTTTTGAAAGCATCACTAAGCAAACACAATTTGCCAGCTATTGGCGGGCACAA
GAAGGCCAAGTTCCTATCCTAGTCGAACAAACCAGCCATCATAAGGGAAGCTTAAGAGCAGAGCATAGCTATGTCACTGG
GGCAGACGATCAAGTCGCTCTAACGGCTTTCAAACGTCGCCCATCAGACAATGCCCTTATCACGCGCAGCTACAATCTCT
CAAACGATAAAACTTGTGACTTTAGCCTAAGCCTGCCAAACTACAATGCTAAGGTCACTAATTTGTTAGAAAAAGACAGC
AAGCAAAGCACACCCAGCCAACTTGGCAAAGCTGAAATTTTAACTCTAGCTTGGAAGAAACAATAA

Upstream 100 bases:

>100_bases
AATACACTCGTGAGTGGTTCTCTTGGGCTAACATGATGTTTTGTGAACTACTTCTTGACTATCTTGGCTTTAGCATTACT
CCTTAGAAAGTGAGGCCACT

Downstream 100 bases:

>100_bases
ACTATTATCATTAGTAATAGATTAACATATTCAAAAAGAGTCTGGGACTATTGTCTCAGACTCTTAAGTTGATTTTAAGT
GATTATTAATACCTTTAACA

Product: alpha-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 901; Mature: 900

Protein sequence:

>901_residues
MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDDYLQVRPEREPEIRQAIASGK
LRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDV
TKAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNLSTVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITE
PLAAMAYEVTSTYPHDQLRYAWKTLTQNHPHDSICGCSVDSVHREMMNRFEKAYEVGHYLAKEAAQQIAGAVNTSDFPTD
SQPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAGLSQSFQVIDVSGNTISEADILDTSIAFDYDLPK
RTFREPYFAIKVRLRLPITLPAMSWKALALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSGVSYQD
LLRFEDCGDIGNEYISRQPTHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRS
QEKAELTLTTLIRMEKNNPRLQFTTSFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQEC
FVSLFDGENGVTIGNYGLNEYEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWRAQ
EGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRPSDNALITRSYNLSNDKTCDFSLSLPNYNAKVTNLLEKDS
KQSTPSQLGKAEILTLAWKKQ

Sequences:

>Translated_901_residues
MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDDYLQVRPEREPEIRQAIASGK
LRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDV
TKAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNLSTVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITE
PLAAMAYEVTSTYPHDQLRYAWKTLTQNHPHDSICGCSVDSVHREMMNRFEKAYEVGHYLAKEAAQQIAGAVNTSDFPTD
SQPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAGLSQSFQVIDVSGNTISEADILDTSIAFDYDLPK
RTFREPYFAIKVRLRLPITLPAMSWKALALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSGVSYQD
LLRFEDCGDIGNEYISRQPTHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRS
QEKAELTLTTLIRMEKNNPRLQFTTSFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQEC
FVSLFDGENGVTIGNYGLNEYEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWRAQ
EGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRPSDNALITRSYNLSNDKTCDFSLSLPNYNAKVTNLLEKDS
KQSTPSQLGKAEILTLAWKKQ
>Mature_900_residues
ATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDDYLQVRPEREPEIRQAIASGKL
RIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQVD
TSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDVT
KAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNLSTVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEP
LAAMAYEVTSTYPHDQLRYAWKTLTQNHPHDSICGCSVDSVHREMMNRFEKAYEVGHYLAKEAAQQIAGAVNTSDFPTDS
QPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAGLSQSFQVIDVSGNTISEADILDTSIAFDYDLPKR
TFREPYFAIKVRLRLPITLPAMSWKALALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSGVSYQDL
LRFEDCGDIGNEYISRQPTHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRSQ
EKAELTLTTLIRMEKNNPRLQFTTSFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECF
VSLFDGENGVTIGNYGLNEYEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWRAQE
GQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRPSDNALITRSYNLSNDKTCDFSLSLPNYNAKVTNLLEKDSK
QSTPSQLGKAEILTLAWKKQ

Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]

COG id: COG0383

COG function: function code G; Alpha-mannosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 38 family [H]

Homologues:

Organism=Escherichia coli, GI1786952, Length=902, Percent_Identity=28.159645232816, Blast_Score=350, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR011330
- InterPro:   IPR011682
- InterPro:   IPR015341
- InterPro:   IPR000602 [H]

Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]

EC number: NA

Molecular weight: Translated: 102379; Mature: 102247

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDD
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC
YLQVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPL
HHHCCCCCCHHHHHHHHCCCEEECEEEEEECCCCCCCCCCHHHHCCCCHHHHHCCCCCCC
GYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQVDTSEKYSSQFSEISWQGPDN
CCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCC
SRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDV
CCEEEEEEEHHHCCCCCCCCCCCHHHEEHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEH
TKAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNLSTVQGEITSQETDGWYTLANTASA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCEE
RIYLKQANTRVSRQLENITEPLAAMAYEVTSTYPHDQLRYAWKTLTQNHPHDSICGCSVD
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
SVHREMMNRFEKAYEVGHYLAKEAAQQIAGAVNTSDFPTDSQPFLLFNTSGHSKTSVTEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
TLTWKKYYFGQRFPKEVYQEAQEYLAGLSQSFQVIDVSGNTISEADILDTSIAFDYDLPK
EEEHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCEEEECCCCH
RTFREPYFAIKVRLRLPITLPAMSWKALALQLGNETAPSATVPLYDDSNQCLENEFLKVM
HHHCCCEEEEEEEEEEEEEECCCCCEEHHEEECCCCCCCCEEEEECCCCHHHHHHHEEEE
IQTDGRLTITDKQSGVSYQDLLRFEDCGDIGNEYISRQPTHDQPFYADQGTTKLNIISNT
EECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEEECCC
AQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPR
HHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHEEEEECCCCC
LQFTTSFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQEC
EEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
FVSLFDGENGVTIGNYGLNEYEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSL
EEEEEECCCCEEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCC
SYSFESITKQTQFASYWRAQEGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRR
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEECCCEECCCCCCEEEHHHHCC
PSDNALITRSYNLSNDKTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKK
CCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHCCCEEEEEEEECC
Q
C
>Mature Secondary Structure 
ATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDD
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEC
YLQVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPL
HHHCCCCCCHHHHHHHHCCCEEECEEEEEECCCCCCCCCCHHHHCCCCHHHHHCCCCCCC
GYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQVDTSEKYSSQFSEISWQGPDN
CCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCC
SRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDV
CCEEEEEEEHHHCCCCCCCCCCCHHHEEHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEH
TKAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNLSTVQGEITSQETDGWYTLANTASA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCEE
RIYLKQANTRVSRQLENITEPLAAMAYEVTSTYPHDQLRYAWKTLTQNHPHDSICGCSVD
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHH
SVHREMMNRFEKAYEVGHYLAKEAAQQIAGAVNTSDFPTDSQPFLLFNTSGHSKTSVTEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
TLTWKKYYFGQRFPKEVYQEAQEYLAGLSQSFQVIDVSGNTISEADILDTSIAFDYDLPK
EEEHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHCCCEEEECCCCH
RTFREPYFAIKVRLRLPITLPAMSWKALALQLGNETAPSATVPLYDDSNQCLENEFLKVM
HHHCCCEEEEEEEEEEEEEECCCCCEEHHEEECCCCCCCCEEEEECCCCHHHHHHHEEEE
IQTDGRLTITDKQSGVSYQDLLRFEDCGDIGNEYISRQPTHDQPFYADQGTTKLNIISNT
EECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEEECCC
AQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPR
HHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHEEEEECCCCC
LQFTTSFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQEC
EEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
FVSLFDGENGVTIGNYGLNEYEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSL
EEEEEECCCCEEEECCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCC
SYSFESITKQTQFASYWRAQEGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRR
CCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEECCCEECCCCCCEEEHHHHCC
PSDNALITRSYNLSNDKTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKK
CCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCHHHCCCEEEEEEEECC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]