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The map label for this gene is insK [H]

Identifier: 94994580

GI number: 94994580

Start: 1131799

End: 1132344

Strand: Direct

Name: insK [H]

Synonym: MGAS10750_Spy1184

Alternate gene names: 94994580

Gene position: 1131799-1132344 (Clockwise)

Preceding gene: 94994579

Following gene: 94994581

Centisome position: 58.43

GC content: 41.58

Gene sequence:

>546_bases
ATGCTACTTGAAATCCTTGATTTATCACGCTCCACCTATTACTATCAAGTGAAGCGACTAGCTCAAGGAGATAAGGATAT
AGAACTAAAGCATGTGATTCGAGAGATTTATGATGAGCATAAAGGTAATTACGGTTATCGTCGTATTCATATGGAGTTGC
GTAACCGAGGATTTGTGGTCAATCATAAGAAAGTTCAACGTCTCATGAAAGTCATGGGCCTAGCAGCCCGCATTCGTCGT
AAGCGCAAGTACTCTTCTTACAAAGGTGAGGTTGGTAAGAAGGCTGATAATCTGATTAAACGTCACTTCGAAGGCTCTAA
ACCTTACGAAAAATGTTACACTGATGTGACGGAGTTGGCCTTACCTGAAAGAAAACTCTTCTTATCACCTGTTCTTGACG
GCTATAACAGTGAGATTATTGATTTCACTCTGTCTCGGTCTCCTAACTTGAAACAGGTTCAAACCATGCTTGAGAAGACT
TTTCCAGCGGATTCATACAGCGGAACTATTCTTCATAGTGACCAGGGGTGGCAATACCAACACTAG

Upstream 100 bases:

>100_bases
CTGTGCTAAAAAAGCTGAGAGAATACCGCTTGAGAGACGAAGCAAAACTCAAAGAGCAACAGAAATCATTCAAGCATTAA
GGAATCAATTTCCCTTAGAG

Downstream 100 bases:

>100_bases
TCCTACCATGATTTTTTAGAGTCTAAAGGTATTCTGCCATCCATGTCCCGCAAAGGGAATAGCCCGGATAACGGCATGAT
GGATTCCTTCTTTGGCATTC

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRR
KRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPERKLFLSPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKT
FPADSYSGTILHSDQGWQYQH

Sequences:

>Translated_181_residues
MLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRR
KRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPERKLFLSPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKT
FPADSYSGTILHSDQGWQYQH
>Mature_181_residues
MLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRR
KRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPERKLFLSPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKT
FPADSYSGTILHSDQGWQYQH

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=186, Percent_Identity=26.8817204301075, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1789981, Length=180, Percent_Identity=47.2222222222222, Blast_Score=171, Evalue=2e-44,
Organism=Escherichia coli, GI1788405, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787263, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786753, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786570, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786490, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 21406; Mature: 21406

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVV
CEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEE
NHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LPERKLFLSPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKTFPADSYSGTILHSDQGWQYQ
CCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
H
C
>Mature Secondary Structure
MLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVV
CEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEE
NHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LPERKLFLSPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKTFPADSYSGTILHSDQGWQYQ
CCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]