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The map label for this gene is gcdB [H]

Identifier: 94994442

GI number: 94994442

Start: 991017

End: 992147

Strand: Direct

Name: gcdB [H]

Synonym: MGAS10750_Spy1046

Alternate gene names: 94994442

Gene position: 991017-992147 (Clockwise)

Preceding gene: 94994441

Following gene: 94994446

Centisome position: 51.16

GC content: 43.15

Gene sequence:

>1131_bases
ATGCTAGACGTACTCAATCAAATGGTCCAATCGTCAGGATTGGCTCATCTAACTGTTAATAATCTTATCATGATTTGCTT
GGCCTGTTTCTTTTTATACCTTGGTATCAAAAAGGAATATGAGCCTTACCTTATGGTACCAATCGCCTTTGGGATTTTAC
TCGTTAATTTGCCTATGGCGGGATTGATGGACCACCCTGCCAATGGTAATCCTGGTGGCCTTCTTTATTACCTATATAAG
GGAACTAGCCTAGGGATTTACCCACCTTTAATTTTTCTTTGTTTGGGGGCATCAACTGACTTTGGTCCCTTGATTGCCAA
TCCTAAAACCATTTTACTAGGAGGCGCAGCACAAGTTGGGATTTTCTTAGCCTTTTTCCTTGCTATTATGTTAGGCATGA
CACCTCAAGAAGCGGCTTCTGTCGGGATTATTGGTGGTGCCGATGGACCAACAGCTATTTATGTGACGACAAAGTTGGCG
CCTGATTTACTCTCTACTATCGCCCTAGCAGCTTATTCTTACATGGCTCTGGTACCTATTATTCAACCTCCCATCATTAA
ACTCTTGACTACCAAGGCGGAACGCCAAGTGAAAATGACTCAAGCAAGAACTGTTTCACAAAAAGAAAAAATCATTTTCC
CGATTATGGTAACAATCTTTGTCAGCCTTTTGGTTCCAAGTGCTACAACCTTGGTTGGCTGTTTGATGCTGGGAAATCTG
GTCAGAGAAATTAAAATTGTTCCTAAAATTGTAGAGAATCTCCAACAAGTGGTTATGTTTTGCATTACTATCATTTTAGG
GTTAACCGTTGGTGCTAAGGCCAATGGAGATCTCTTTTTATCAGCCACAACCTTGAAAATTATTGCCCTTGGGCTAATCG
CCTTTGCTGCTGGGACAGCAGGGGGTGTCTTGATGGGGAAAATCATGTACTATTTATCTGGTAACAAAGTGAACCCTATG
ATAGGAGCAGCAGGTGTTTCAGCTGTTCCGATGGCAGCACGAGTGGTCCAAAAGGTCGGACAAGAAGAAGATCCAAGTAA
TTTCTTACTCATGCACGCCATGGGGCCCAATGTAGCTGGCGTTATTGGCTCAGCCATTGCCTCAGGTGCCTTGCTGGCCT
TCTTTGGCTAA

Upstream 100 bases:

>100_bases
AATTCTAGCACCTGCAGATGGTCTGGTTTCAAAAATTCATGTTGTGGCTAACCAAACGGTCGAGTCTGAACAAGTTTTGA
TTTCATTCTAGGAGGAAACC

Downstream 100 bases:

>100_bases
TTGTGAAAAAGGATTAGTAAATTAATCTTAATAAATCATTATCAGGAGTTGGAAGCAATCCAGCTCCTTTTTTAGTAGAA
AGCTCGAGTGATAAACTATT

Product: Na+ transporting oxaloacetate decarboxylase beta chain

Products: NA

Alternate protein names: Carboxylyase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYLMVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYK
GTSLGIYPPLIFLCLGASTDFGPLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVTIFVSLLVPSATTLVGCLMLGNL
VREIKIVPKIVENLQQVVMFCITIILGLTVGAKANGDLFLSATTLKIIALGLIAFAAGTAGGVLMGKIMYYLSGNKVNPM
IGAAGVSAVPMAARVVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG

Sequences:

>Translated_376_residues
MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYLMVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYK
GTSLGIYPPLIFLCLGASTDFGPLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVTIFVSLLVPSATTLVGCLMLGNL
VREIKIVPKIVENLQQVVMFCITIILGLTVGAKANGDLFLSATTLKIIALGLIAFAAGTAGGVLMGKIMYYLSGNKVNPM
IGAAGVSAVPMAARVVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG
>Mature_376_residues
MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYLMVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYK
GTSLGIYPPLIFLCLGASTDFGPLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVTIFVSLLVPSATTLVGCLMLGNL
VREIKIVPKIVENLQQVVMFCITIILGLTVGAKANGDLFLSATTLKIIALGLIAFAAGTAGGVLMGKIMYYLSGNKVNPM
IGAAGVSAVPMAARVVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG

Specific function: Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD) [H]

COG id: COG1883

COG function: function code C; Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcdB/mmdB/oadB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005661 [H]

Pfam domain/function: PF03977 OAD_beta [H]

EC number: =4.1.1.70 [H]

Molecular weight: Translated: 39509; Mature: 39509

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYLMVPIAFGILLVNLPMA
CHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCHH
GLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFGPLIANPKTILLGGAAQVG
HHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHH
IFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLAPDLLSTIALAAYSYMALVPI
HHHHHHHHHHHCCCCHHHCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
IQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVTIFVSLLVPSATTLVGCLMLGNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VREIKIVPKIVENLQQVVMFCITIILGLTVGAKANGDLFLSATTLKIIALGLIAFAAGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCC
GGVLMGKIMYYLSGNKVNPMIGAAGVSAVPMAARVVQKVGQEEDPSNFLLMHAMGPNVAG
CHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
VIGSAIASGALLAFFG
HHHHHHHHCCHHEECC
>Mature Secondary Structure
MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYLMVPIAFGILLVNLPMA
CHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHCCHH
GLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFGPLIANPKTILLGGAAQVG
HHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHH
IFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLAPDLLSTIALAAYSYMALVPI
HHHHHHHHHHHCCCCHHHCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
IQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVTIFVSLLVPSATTLVGCLMLGNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VREIKIVPKIVENLQQVVMFCITIILGLTVGAKANGDLFLSATTLKIIALGLIAFAAGTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCC
GGVLMGKIMYYLSGNKVNPMIGAAGVSAVPMAARVVQKVGQEEDPSNFLLMHAMGPNVAG
CHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHH
VIGSAIASGALLAFFG
HHHHHHHHCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10027965 [H]