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The map label for this gene is ywlC [H]

Identifier: 94994410

GI number: 94994410

Start: 960948

End: 961568

Strand: Direct

Name: ywlC [H]

Synonym: MGAS10750_Spy1014

Alternate gene names: 94994410

Gene position: 960948-961568 (Clockwise)

Preceding gene: 94994409

Following gene: 94994411

Centisome position: 49.61

GC content: 38.0

Gene sequence:

>621_bases
TTGGCAAAGAAAGGATGGTGGTTGTTGATTATGGAGTATCTAGCTAGTATCATTGAATTAGGTGATGCCCTTGTTTTGCC
AACAGAAACGGTTTATGGTCTTTTCGCCAAGGCTTTAGATGAAAAAGCAGTAAATGCTGTTTATGACTTAAAACAAAGAC
CCCGAGATAAAGCAATGAACCTTAATGTGGCTGATTTTAATAGTATCTTAGCCTTTTCAAAAGAACAGCCGAGATACCTC
AAGAAATTATACCAAGCCTTTTTACCAGGTCCGTTAACGATTATTTTAAAAGCTAATGACCAGGTTCCTTATTGGATTAA
TTCGGGTCTTTCAACGGTTGGTTTTCGCTTACCCAGTCATCCAATTACCGCAGCTTTAATTCAAAAAACAGGCCCTTTAA
TTGGTCCTTCTGCAAACTTATCTGGCAAAGCTAGTGGTCGAGTTTTTGATCATATTATGCAAGATTTTGACTTTCAAGTG
TTTGGTTATGCAGATGATCCTTTTCTAACAGGTAAGGATTCAACCATCTTAGACTTATCAGGTGAGTGTGCTGTGATTTT
ACGTCAAGGTGCTATCACCAAAGAAGAATTATTAGCCAACGTGCCTGAACTTCGCTTTTAA

Upstream 100 bases:

>100_bases
AAGCTTTACTTTGAAATTGGTTATAAGCAAGCTGAAGGTATAAAAGATATGTTACAAGCCTATTTTCCTCAAAGACATAT
ACGAGTCGTAACGGATATAT

Downstream 100 bases:

>100_bases
GAGAGGAGCCGCTTGGAATGTTGAGACCATTAAGTAAAACGGACTGTCCTATGCTACAAGAAATTAACGCCAAAGCCCTT
GGCTATTTAGTTTCGCTTGA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MAKKGWWLLIMEYLASIIELGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSILAFSKEQPRYL
KKLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQV
FGYADDPFLTGKDSTILDLSGECAVILRQGAITKEELLANVPELRF

Sequences:

>Translated_206_residues
MAKKGWWLLIMEYLASIIELGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSILAFSKEQPRYL
KKLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQV
FGYADDPFLTGKDSTILDLSGECAVILRQGAITKEELLANVPELRF
>Mature_205_residues
AKKGWWLLIMEYLASIIELGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMNLNVADFNSILAFSKEQPRYLK
KLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVF
GYADDPFLTGKDSTILDLSGECAVILRQGAITKEELLANVPELRF

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=136, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081864, Length=184, Percent_Identity=26.6304347826087, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=182, Percent_Identity=29.6703296703297, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=211, Percent_Identity=30.3317535545024, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 22821; Mature: 22690

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKGWWLLIMEYLASIIELGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMN
CCCCCHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
LNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSH
CCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHEECCCC
PITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLTGKDSTILDLS
CHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCEECCCCCEEEEEC
GECAVILRQGAITKEELLANVPELRF
CCEEEEEECCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AKKGWWLLIMEYLASIIELGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRPRDKAMN
CCCCHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
LNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLSTVGFRLPSH
CCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHEECCCC
PITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLTGKDSTILDLS
CHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCEECCCCCEEEEEC
GECAVILRQGAITKEELLANVPELRF
CCEEEEEECCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]