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The map label for this gene is folQ [H]

Identifier: 94994370

GI number: 94994370

Start: 923735

End: 924094

Strand: Direct

Name: folQ [H]

Synonym: MGAS10750_Spy0974

Alternate gene names: 94994370

Gene position: 923735-924094 (Clockwise)

Preceding gene: 94994369

Following gene: 94994371

Centisome position: 47.69

GC content: 40.83

Gene sequence:

>360_bases
ATGGATAAAATCGTATTAGAAGGTTGCCGTTTTTATGGCTACCATGGAGCCTTTAAAGAAGAACAGACCCTTGGGCAAAT
TTTTCTGGTTGATTTAGAATTGTCAGTCGATTTGCAAGCAGCTTCTTTGTCAGACCAATTAACAGATACGGTCCATTACG
GGATGGTGTTTGATAGTGTCCGTCAGTTAGTGGAAGGGGGAAAGTTTATTTTGATTGAACGTTTAGCAGGTGCGATTTGT
GAACAGCTTTTTAACGAATTTCCACCTATTGAAGCCATCAAAGTGGCCATTAAAAAGGAAAACCCACCGATTGCAGGCCA
CTATAAGGCAGTTGGTATTGAATTGGAGAGACAGAGATGA

Upstream 100 bases:

>100_bases
TGCTTATGCCCTTGGAAAAGGCTGTCAGATTGTACGCGTACACGATGTCAAGGCTAATCAAGACATTGTGGCTGTTTTGA
GCTAGTTGATGTGAGGACTT

Downstream 100 bases:

>100_bases
CCATTGTTTATTTAAGTTTAGGCACCAATATGGGGGACCGAGCAGCTTACTTGCAAAAAGCTCTTGAGGCTTTAGCTGAC
TTACCTCAAACACGGTTGCT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGGKFILIERLAGAIC
EQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR

Sequences:

>Translated_119_residues
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGGKFILIERLAGAIC
EQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
>Mature_119_residues
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSVRQLVEGGKFILIERLAGAIC
EQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13370; Mature: 13370

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSV
CCCEEEECHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHH
RQLVEGGKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
HHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLSDQLTDTVHYGMVFDSV
CCCEEEECHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHH
RQLVEGGKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENPPIAGHYKAVGIELERQR
HHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]