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The map label for this gene is srtA [H]

Identifier: 94994351

GI number: 94994351

Start: 907659

End: 907799

Strand: Direct

Name: srtA [H]

Synonym: MGAS10750_Spy0955

Alternate gene names: 94994351

Gene position: 907659-907799 (Clockwise)

Preceding gene: 94994350

Following gene: 94994352

Centisome position: 46.86

GC content: 33.33

Gene sequence:

>141_bases
ATGACTAACACAATTAAAGACTTTGATCTCGATTTGAAAACAAATAAAAAAGACACTGCTACACCTTATGTTGGTAGCCG
TTACCTATGTACCCCTGGTTCTTGTTGGAAATTAGTTTGCTTTACAACAACTGTTAAATAA

Upstream 100 bases:

>100_bases
TTGGCTAAAATACTTTTTTTCTGAACAAATTCTGAACTTGGGGTGTCATAATAATCATGTAAATATATCGGATGCAAAAA
CGTAAGAGAGGAACTAGAAA

Downstream 100 bases:

>100_bases
TAAAGTTATCATTATCATCAACATTATAATTTCAAATAATTTGATATATTTATAAATTTAGGGGAGTAGACTGATTTTAG
TTTGCTCCTTTATTAGTAGA

Product: lantibiotic srtA precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 46; Mature: 45

Protein sequence:

>46_residues
MTNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK

Sequences:

>Translated_46_residues
MTNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
>Mature_45_residues
TNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK

Specific function: Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous tran

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type A lantibiotic family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006079 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 5206; Mature: 5075

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
6.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
CCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEEECC
>Mature Secondary Structure 
TNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTTVK
CCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]