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The map label for this gene is msrB [H]

Identifier: 94994325

GI number: 94994325

Start: 885973

End: 886410

Strand: Direct

Name: msrB [H]

Synonym: MGAS10750_Spy0929

Alternate gene names: 94994325

Gene position: 885973-886410 (Clockwise)

Preceding gene: 94994324

Following gene: 94994326

Centisome position: 45.74

GC content: 43.15

Gene sequence:

>438_bases
ATGGAAACATCAGATGAGTTAAAACAACGCATTGGTGATCTTTCTTACGAGGTCACCCAGCATGCAGCAACAGAATCTCC
CTTTACAGGGAAATATGATGATTTTTTTGAGAAGGGTATCTATGTCGATATCGTCAGTGGTGAGGTCTTGTTTTCATCAC
TGGATAAATTTAATTCTGGCTGTGGTTGGCCTGCCTTCTCAAAACCTATTGAAAATCGCATGGTCACGAACCACGATGAC
TCTTCTTATGGGATGAGACGAGTTGAGGTTAAAAGCCGTGAAGCAGGATCGCATTTGGGGCATGTCTTTAGTGACGGCCC
CAAAGAAGCTGGAGGCTTGCGTTACTGTATCAATTCAGCAGCTCTTAAATTCATTCCTTATGACCAGATGGAAAAAGGAG
GCTATGCCCAATGGCTCACATTGTTTGATGAGACATAA

Upstream 100 bases:

>100_bases
TAGGTATAAAGTCTTGTCTGAGGTGCTGTGAACAAATCAGTTACCCTTCACCTCTTTTTTTGGTAAAATGTAAGCACTAA
AACATCAAAAGGAGTTTTCT

Downstream 100 bases:

>100_bases
CAGGGTTTCAAAATGACTAAAAAAGAAGCGTCAGTGATTCCCATAAGCACTGGATTGGTGAGGCGTACGGGTCAATTTTA
CAAGCCTTTGTAAAAGGTCT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDD
SSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKGGYAQWLTLFDET

Sequences:

>Translated_145_residues
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDD
SSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKGGYAQWLTLFDET
>Mature_145_residues
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDD
SSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKGGYAQWLTLFDET

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=126, Percent_Identity=50, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI301336162, Length=126, Percent_Identity=50, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI73089054, Length=126, Percent_Identity=50, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI37620216, Length=126, Percent_Identity=50, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI117606353, Length=129, Percent_Identity=38.7596899224806, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=40.9836065573771, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17553450, Length=124, Percent_Identity=45.9677419354839, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=124, Percent_Identity=45.9677419354839, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=119, Percent_Identity=38.655462184874, Blast_Score=78, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=48.8, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=48.8, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=48.8, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378664, Length=122, Percent_Identity=48.3606557377049, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI221378662, Length=129, Percent_Identity=45.7364341085271, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24645804, Length=136, Percent_Identity=44.1176470588235, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645801, Length=136, Percent_Identity=44.1176470588235, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16282; Mature: 16282

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSG
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECHHHHHHHHHHHCCC
CGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSA
CCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALKFIPYDQMEKGGYAQWLTLFDET
HHEECCCHHHCCCCCEEEHEEECCC
>Mature Secondary Structure
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSG
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHCCCEEEEECHHHHHHHHHHHCCC
CGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSA
CCCCCCCCCHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALKFIPYDQMEKGGYAQWLTLFDET
HHEECCCHHHCCCCCEEEHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]