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The map label for this gene is glmM [H]

Identifier: 94994311

GI number: 94994311

Start: 869769

End: 871124

Strand: Direct

Name: glmM [H]

Synonym: MGAS10750_Spy0915

Alternate gene names: 94994311

Gene position: 869769-871124 (Clockwise)

Preceding gene: 94994310

Following gene: 94994312

Centisome position: 44.9

GC content: 42.55

Gene sequence:

>1356_bases
ATGGGAAAATATTTTGGAACAGATGGTGTTCGTGGTGAAGCAAATGTTGAGCTGACACCTGAGTTAGCTTTTAAACTGGG
CCGATTCGGTGGTTATGTTTTGAGTCAACATGAGACCGAAAGACCTAAAGTTTTTGTGGCGCGTGACACCCGTATTTCAG
GAGAAATGTTGGAGTCAGCCTTGATTGCTGGTCTACTATCTGTTGGTATTGAAGTTTATAAACTTGGTGTTTTAGCGACA
CCTGGTGTCTCTTATTTAGTTAGAACTGAAAAAGCAAGTGCAGGTGTGATGATTTCTGCAAGTCATAACCCTGCGCTTGA
CAATGGCATCAAATTCTTTGGGAATGACGGGTTTAAGTTAGCTGATGACCAAGAATTGGAAATTGAAGCTCTCTTAGATG
CTCCGGAGGACACGCTTCCTCGCCCGAGTGCAGAAGGACTTGGAACCTTGGTAGATTATCCAGAAGGACTTCGTAAATAT
GAAAAGTTCTTGGTAACAACAGGTACTGACTTAAGCGGTATGACAGTTGCCTTAGACACTGCTAATGGAGCTGCTTCAGT
GTCAGCACGTGATGTCTTTTTAGATTTAAATGCAGAAATTGCTGTCATTGGCGAAAAACCAAATGGTCTTAATATTAATG
ACGGTGTTGGTTCAACGCATCCAGAACAACTTCAAGAGTTAGTTAAGGAAACAGGAGCAGATCTTGGTTTAGCCTTTGAT
GGCGATAGCGACCGTCTGATTGCCGTGGACGAAACTGGCGAGATTGTTGACGGTGATCGTATTATGTTTATCATTGGTAA
ATACTTGTCAGAAAAAGGGCTTCTTGCTCACAATACCATTGTCACAACGGTGATGTCTAACCTCGGTTTTCATAAAGCTT
TAGATAAACAAGGTATTAATAAAGCAATTACAGCAGTTGGAGACCGCTATGTGGTTGAAGAAATGCGTAGCTCAGGATAC
AATCTCGGTGGTGAACAATCAGGCCATGTCATTATCATGGACTACAATACCACTGGAGATGGTCAGTTGACAGCTATCCA
ATTAGCCAAGGTGATGAAGGAAACTGGGAAATCACTTTCGGAATTAGCTGCTGAAGTAACCATTTACCCTCAAAAACTGG
TGAATATTCGTGTGGAAAACAGCATGAAAGACCGTGCTATGGAAGTTCCAGCTATTGCGAACATCATTGCAAAAATGGAG
GATGAAATGGCTGGTAATGGTCGTATTCTCGTGAGACCAAGTGGTACAGAACCTCTTCTTCGTGTCATGGCAGAGGCGCC
AACAGATGCCGAAGTTGATTATTATGTCGATACTATTGCTGATGTCGTCCGTACAGAAATCGGATGCGATAACTAA

Upstream 100 bases:

>100_bases
TTGAGCCGTCAGTAGTGACCGTTCAGTTGACAACCACCAAAAAATAATGGATAATAACTAGGAAAATTGAATGGAGGAAG
CCATTAGGCTTATATAAATT

Downstream 100 bases:

>100_bases
CGAGTTGAGTACAAACAAGAAACCTTATTTCTAAGGCTTCTGTCAACAATTGGAAAGAGGCTTGGGGCGTTTAGCCCAAG
TCTCTTTTTATAAATTGCTA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLAT
PGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFD
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGY
NLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKME
DEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

Sequences:

>Translated_451_residues
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLAT
PGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFD
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGY
NLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKME
DEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>Mature_450_residues
GKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATP
GVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYE
KFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDG
DSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYN
LGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMED
EMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=43.7219730941704, Blast_Score=314, Evalue=6e-87,
Organism=Escherichia coli, GI1788361, Length=452, Percent_Identity=25.6637168141593, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 48381; Mature: 48250

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESA
CCCCCCCCCCCCCCCEEECHHHHHHHHHCCCEEECCCCCCCCEEEEEECCCCCHHHHHHH
LIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKL
HHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCEE
ADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDT
CCCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHEEEECCCCCCCEEEEEEC
ANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFD
CCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGIN
CCCCCEEEEECCCCEECCCEEEEEEEHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHCCCH
KAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLS
HHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHH
ELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLL
HHHHHEEEECHHEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
RVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESA
CCCCCCCCCCCCCCEEECHHHHHHHHHCCCEEECCCCCCCCEEEEEECCCCCHHHHHHH
LIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKL
HHHHHHHHCCEEEEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEECCCCCEE
ADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDT
CCCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHHHHHEEEECCCCCCCEEEEEEC
ANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFD
CCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
GDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGIN
CCCCCEEEEECCCCEECCCEEEEEEEHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHCCCH
KAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLS
HHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHH
ELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLL
HHHHHEEEECHHEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
RVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]