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The map label for this gene is deoD [H]

Identifier: 94994187

GI number: 94994187

Start: 765097

End: 765810

Strand: Direct

Name: deoD [H]

Synonym: MGAS10750_Spy0791

Alternate gene names: 94994187

Gene position: 765097-765810 (Clockwise)

Preceding gene: 94994186

Following gene: 94994188

Centisome position: 39.5

GC content: 42.02

Gene sequence:

>714_bases
ATGTCTATCCATATTTCTGCCAAAAAAGGCGATATTGCTGATAAAATTCTTCTACCTGGAGACCCTTTGCGCGCGAAATT
TATCGCTGAAAATTTCCTAGAAGATGCAGTGTGTTTTAACGAAGTGCGTAACATGTTTGGCTACACAGGAACTTACAAAG
GGCACCGCGTTTCTGTCATGGGAACTGGTATGGGAATGCCTTCGATCTCTATCTATGCTCGTGAATTAATCGTTGATTAC
GGTGTCAAAACATTGATCCGTGTTGGTACTGCGGGTGCGATTGACCCAGAAGTTCATGTGCGTGAATTGGTGCTTGCCCA
AGCAGCAGCAACCAACTCAAATATTATCCGTAATGACTTCCCAGAATTTGATTTCCCACAAATTGCTGATTTTGGTTTAC
TTGACAAGGCTTACCATATCGCCAGAGAAATGGGAGTAACAACTCACGTTGGGAATGTGCTTTCTTCTGATGTCTTTTAC
ACTAACATGCCTGAGCGTAATATGGTTCTTGGTAAATTGGGTGTTAAAGCCATCGAAATGGAAGCAGCAGCTCTTTACTA
TTTAGCTGCTCAGCACCATGTCAAAGCCCTTGGAATCATGACGATCTCAGATAACTTGAATGATCCAACCGAAGATACTA
CAGCTGAAGAGCGCCAAACCACTTTCACTGATATGATGAAAATTGGTTTGGAAACTTTAATTGCCAATGACTAA

Upstream 100 bases:

>100_bases
TAAGGACTTGGTCAAAAAGATAAGTTGTCTAGAAAATCAGGATTTTCTGCCAACTTCCTATTTTGCCATCGTTCTTTTAA
CGCCCTCAGTATCATAATTT

Downstream 100 bases:

>100_bases
TAATCAAACGCTAGACATCCTTTTGGATGTCTATGCTTATAATCACGTCTTTAGAATTGCTAAAGCCTTGCCAAATATCC
CTAAAACTGTTCTCTATTTA

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDY
GVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
TNMPERNMVLGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKIGLETLIAND

Sequences:

>Translated_237_residues
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDY
GVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
TNMPERNMVLGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKIGLETLIAND
>Mature_236_residues
SIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYG
VKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYT
NMPERNMVLGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKIGLETLIAND

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=51.7094017094017, Blast_Score=243, Evalue=7e-66,
Organism=Escherichia coli, GI1790265, Length=209, Percent_Identity=31.5789473684211, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 26062; Mature: 25931

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVM
CEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDF
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCC
PEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNMPERNMVLGKLGVKAIEM
CCCCCCCHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCEEHHHHCCCHHHH
EAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKIGLETLIAND
HHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVM
EEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
GTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELVLAQAAATNSNIIRNDF
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCC
PEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNMPERNMVLGKLGVKAIEM
CCCCCCCHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCEEHHHHCCCHHHH
EAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTFTDMMKIGLETLIAND
HHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA