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The map label for this gene is mur1-1 [H]

Identifier: 94994150

GI number: 94994150

Start: 732307

End: 732900

Strand: Direct

Name: mur1-1 [H]

Synonym: MGAS10750_Spy0754

Alternate gene names: 94994150

Gene position: 732307-732900 (Clockwise)

Preceding gene: 94994149

Following gene: 94994151

Centisome position: 37.8

GC content: 37.04

Gene sequence:

>594_bases
GTGAAAAAAAGGAGAAGAAGGGCTAAATCATCCGTAAATCGACTTGTCTTAGGGTTAGTATTACTTAATCTGATTGTTAG
TATGTGGACATTAAAATTGGGAAACCAGCGATTAGCTCCGTATGCGGATCACGAAACTCTGACATTTGTCAGGAAGATTA
GTCATGCTGCTCAATCAGTCGCTCAAAAGAAACAGTTATACAGTTCGGTGATGATGGCTCAGGCCATTTTAGAATCCAAT
AATGGCAAGTCACAACTAAGTCAAAAACCTTATTATAATTTTTTCGGGATTAAGGGGAGCTATAAAGAACGGTCAGTCAT
TTTTCCAACTTTAGAAGACGATGGACAAGGGAATCTTTATCAAATTGATGCTACTTTTCGTTCCTATGGGAGCCTGACAG
CTTGTTTTTTAGATTACGCAAGAGTTTTGAATGATCCACTTTATGACAAAACCCACAAAAAGTTTTGGTCTCATTATCAA
GATGCTACTGCAACCTTAACAGGCACTTACGCCACTGATACAACTTACCATACCAAATTAAATGAATTGATTGAATGGTA
TCAACTCACTAATTTTGATGGTCTAATGAAATAG

Upstream 100 bases:

>100_bases
AAAAGGTAAAGAACTTTTTTCTTACTAAAACTAGAATCTGTCAAGGTTCTAGTTTTTTGCTATACTAGAGTTAAAGGATA
AGAAATGAGGACCTCTGAAG

Downstream 100 bases:

>100_bases
TTATCCACAATTTTAAAAAAAATCAGAAGAAATATGTCGATTTCAAGACAAAAGTTATCAATCTCATTAAATTATCTGTG
GAAAAGTTAATTTAAACGTT

Product: N-acetylmuramidase

Products: NA

Alternate protein names: Autolysin; Lysozyme; Peptidoglycan hydrolase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESN
NGKSQLSQKPYYNFFGIKGSYKERSVIFPTLEDDGQGNLYQIDATFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSHYQ
DATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK

Sequences:

>Translated_197_residues
MKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESN
NGKSQLSQKPYYNFFGIKGSYKERSVIFPTLEDDGQGNLYQIDATFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSHYQ
DATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK
>Mature_197_residues
MKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESN
NGKSQLSQKPYYNFFGIKGSYKERSVIFPTLEDDGQGNLYQIDATFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSHYQ
DATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK

Specific function: Hydrolyzes the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013338
- InterPro:   IPR002901
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01832 Glucosaminidase; PF01476 LysM [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 22687; Mature: 22687

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLTFVRKISHAAQSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGSYKERSVIFPTLEDDGQGNLY
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEE
QIDATFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSHYQDATATLTGTYATDTTYHTKL
EEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHH
NELIEWYQLTNFDGLMK
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYADHETLTFVRKISHAAQSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGSYKERSVIFPTLEDDGQGNLY
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEE
QIDATFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSHYQDATATLTGTYATDTTYHTKL
EEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHEEEECCCCCCHHHHHH
NELIEWYQLTNFDGLMK
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11131071 [H]