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The map label for this gene is fruB [H]

Identifier: 94994148

GI number: 94994148

Start: 729354

End: 730265

Strand: Direct

Name: fruB [H]

Synonym: MGAS10750_Spy0752

Alternate gene names: 94994148

Gene position: 729354-730265 (Clockwise)

Preceding gene: 94994147

Following gene: 94994149

Centisome position: 37.65

GC content: 40.24

Gene sequence:

>912_bases
ATGATTTATACCGTGACCTTAAACCCTTCTATTGACTTTATTGTCAGAATTGACCAAATAAATCTTGGGTCAGTGAATCG
CATGGCGAGTGATGATAAGTTTGCTGGAGGTAAAGGCATTAATGTGAGTCGCATCTTGCAACGTTTAGACATTGCTAGCA
CGGCGACAGGGTTCTTGGGTGGTTTTACAGGACGTTTTATCGAAGAAAGTTTGAGTGCAGAAGGCGTTAAAACTGATTTT
GTAAAAGGTGATCAAGTTACTCGAATCAATGTTAAAATCAAGTCACAAGAAGAGACCGAATTAAATGGTCAAGGACCTAT
CATTAGTCAGGAACAACTAGAGGAGTTGAAAACTAAGCTTTCCCAGCTAACAGCAGAGGATACAGTTGTCTTTGCAGGTT
CAGCGCCAGCTAATCTTGGCAATGCTGTTTATAAGGAATTACTTCCTTTAGTTAGGCAAAGCGGTGCTCAGGTGGTTTGT
GATTTTGAAGGACAGACTTTAATAGATGCGCTTACATATAATCCTCTGTTGGTTAAACCTAATAATCATGAACTAGAAGC
TATTTTTGGTACGATTCTGACTAGTCTTGATGATGTTGAAACCTATGCCCGTCGTCTTTTAGAGATGGGTGCTCAAAATG
CCATCATTTCAATGGCTGGTGATGGTGCTTTGCTGGTTACTAAAGAAGCGACTTATTTTGCTAAACCGATTAAGGGAGAA
GTTAAAAATTCTGTCGGTGCTGGTGATTCGATGGTTGCTGGCTTTACAGGCGAATTTATGAAGAGTCAAAATCCAATAGA
AGCCTTAAAATGGGGCGTGGCTTGTGGTACAGCGACGGCTTTCTCTGATGACTTGGCGACAATTGCATTTATTAAGGAAA
CATATCATAAAGTTGAGGTAGAAAAACGATGA

Upstream 100 bases:

>100_bases
TTGTAAAAGTAGCTCCTATTAATGATGTGACTATTATTACATTAGGAGGATCAGCAAGTATTCTTAAACAAATAAAGGAA
AAGGCAAAGGTGATTGAATT

Downstream 100 bases:

>100_bases
AAATTCAAGATTTATTGAGAAAAGATATTATGATTCTCGATTTACAGGCTATTTCTAAAGAAGTTGCCATTGACGAGATG
ATTACTAAATTAGTTGAAAA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDF
VKGDQVTRINVKIKSQEETELNGQGPIISQEQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNAIISMAGDGALLVTKEATYFAKPIKGE
VKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAFSDDLATIAFIKETYHKVEVEKR

Sequences:

>Translated_303_residues
MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDF
VKGDQVTRINVKIKSQEETELNGQGPIISQEQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNAIISMAGDGALLVTKEATYFAKPIKGE
VKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAFSDDLATIAFIKETYHKVEVEKR
>Mature_303_residues
MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDF
VKGDQVTRINVKIKSQEETELNGQGPIISQEQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNAIISMAGDGALLVTKEATYFAKPIKGE
VKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAFSDDLATIAFIKETYHKVEVEKR

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=257, Percent_Identity=34.6303501945525, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788017, Length=286, Percent_Identity=30.0699300699301, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32722; Mature: 32722

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSRILQRLDIASTATGFLG
CEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GFTGRFIEESLSAEGVKTDFVKGDQVTRINVKIKSQEETELNGQGPIISQEQLEELKTKL
HHHHHHHHHHHCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
SQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCDFEGQTLIDALTYNPLLVKP
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHCCCCEEECC
NNHELEAIFGTILTSLDDVETYARRLLEMGAQNAIISMAGDGALLVTKEATYFAKPIKGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCHHHHCCCCHH
VKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAFSDDLATIAFIKETYHKVEV
HHHCCCCCCCEEECCCHHHHCCCCCHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHEEE
EKR
CCC
>Mature Secondary Structure
MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSRILQRLDIASTATGFLG
CEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GFTGRFIEESLSAEGVKTDFVKGDQVTRINVKIKSQEETELNGQGPIISQEQLEELKTKL
HHHHHHHHHHHCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
SQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCDFEGQTLIDALTYNPLLVKP
HHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEHHHCCCCEEECC
NNHELEAIFGTILTSLDDVETYARRLLEMGAQNAIISMAGDGALLVTKEATYFAKPIKGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCHHHHCCCCHH
VKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAFSDDLATIAFIKETYHKVEV
HHHCCCCCCCEEECCCHHHHCCCCCHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHEEE
EKR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]