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The map label for this gene is trxB [C]

Identifier: 94994144

GI number: 94994144

Start: 725224

End: 726216

Strand: Direct

Name: trxB [C]

Synonym: MGAS10750_Spy0748

Alternate gene names: 94994144

Gene position: 725224-726216 (Clockwise)

Preceding gene: 94994143

Following gene: 94994145

Centisome position: 37.44

GC content: 37.16

Gene sequence:

>993_bases
GTGAAAGATAAAGCATATGATATTACGATTATTGGTGGTGGTCCAATAGGTTTATTTGCAGCCTTTTATGCAGGTCTTAG
GGGCGTAACAGTAAAGATTATTGAGAGTTTGTCAGAACTTGGTGGACAGCCTGCCATTCTTTATCCTGAGAAAATGATTT
ATGATATTCCAGCTTATCCATCTTTAACAGGTGTTGAGTTGACAGAAAATTTAATAAAACAATTAAGCCGTTTTGAAGAT
CGTACAACCATTTGTTTAAAAGAAGAAGTATTAACCTTTGACAAGGTTAAAGGTGGTTTTTCGATTAGGACTAATAAGGC
AGAGCATTTTTCAAAAGCCATTATCATTGCTTGTGGAAATGGCGCTTTTGCACCAAGAACTTTAGGGTTAGAAAGTGAGG
AAAACTTTGCTGATCATAACCTTTTTTATAATGTTCACCAGTTGGACCAGTTTGCGGGACAAAAAGTTGTGATTTGTGGT
GGTGGAGATTCAGCAGTTGATTGGGCTTTGGCTTTAGAAGATATTGCTGAGAGTGTGACGGTTGTGCACCGTCGTGATGC
TTTCAGAGCACATGAACACAGTGTGGAATTATTGAAAGCATCAACGGTCAACCTCTTAACACCTTATGTGCCAAAAGCAT
TGAAAGGAATTGGAAACCTGGCTGAAAAATTAGTTATTCAAAAAGTGAAAGAAGATGAAGTGTTAGAACTTGAATTGGAC
AGTCTTATTGTTAGTTTTGGTTTTTCAACTTCTAATAAGAATTTGAAAAATTGGAATCTCGACTATAAGCGTTCAAGTAT
TACTGTTTCACCACTTTTTCAAACAAGTCAAGAAGGTGTTTTTGCCATTGGTGATGCAGCCGCTTATAATGGGAAAGTGG
ATTTGATTGCTACTGGTTTTGGCGAAGCACCAACAGCAGTTAATCAGGCTATTAACTATATTTATCCAGATCGAGATAAC
CGTGTGGTGCATTCAACCTCTTTAATTGACTAA

Upstream 100 bases:

>100_bases
ATTTGAGAAGGCCAGATTTGTTAGAGCGGTACGATTTTTCCGAGGAAGAGCGCAAGCTATTGGATAAGATTAAAGAAGCA
TTGGGTTAAGGAGAAGATTA

Downstream 100 bases:

>100_bases
GGGAGTCGGAAGTTTCAAGAGCAGTAGCAACAGCTAATATTCAGTTTGTCAGGATAGGACAAATGGTTTTTACCTAAGTC
TTCGTGACAAGTTTTATACT

Product: Thioredoxin reductase

Products: NA

Alternate protein names: FNR; Fd-NADP+ reductase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFED
RTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGVFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDN
RVVHSTSLID

Sequences:

>Translated_330_residues
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFED
RTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGVFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDN
RVVHSTSLID
>Mature_330_residues
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFED
RTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGVFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDN
RVVHSTSLID

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=298, Percent_Identity=30.2013422818792, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321898, Length=296, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 36104; Mature: 36104

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYP
CCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCHHHEEECCCCC
SLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGN
CCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEECCCHHHCCEEEEEEECC
GAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVT
CCCCCEEECCCCCCCCCCCHHEEEHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
HHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGVFAIGDAAAYNGKVDLIATGF
HEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEECCCCCCCEEEEEEECC
GEAPTAVNQAINYIYPDRDNRVVHSTSLID
CCCCHHHHHHHHEECCCCCCEEEECCCCCC
>Mature Secondary Structure
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYP
CCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCHHHEEECCCCC
SLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGN
CCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEECCCHHHCCEEEEEEECC
GAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVT
CCCCCEEECCCCCCCCCCCHHEEEHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
HHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGVFAIGDAAAYNGKVDLIATGF
HEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEECCCCCCCEEEEEEECC
GEAPTAVNQAINYIYPDRDNRVVHSTSLID
CCCCHHHHHHHHEECCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]