Click here to switch to the map view.

The map label for this gene is ywbI [H]

Identifier: 94994121

GI number: 94994121

Start: 700062

End: 700976

Strand: Direct

Name: ywbI [H]

Synonym: MGAS10750_Spy0725

Alternate gene names: 94994121

Gene position: 700062-700976 (Clockwise)

Preceding gene: 94994120

Following gene: 94994122

Centisome position: 36.14

GC content: 36.07

Gene sequence:

>915_bases
ATGAATATTCAACAATTACGCTATGTGGTAGCCATCGCTAATAATGGAACTTTTCGAGAAGCTGCCTCTAAATTGTTTGT
CAGTCAGCCTAGCTTATCAGTTTCTATCAAAGATTTAGAGGCGGAATTAGGGTTTCAAATTTTTAATCGGACTACTTCAG
GAACAGTCTTGACAAGTCAAGGACTAGTTTTTTATGAGAAAGCTTTAGAAGTAGTCAAATCTTTTGATTCTTTTGAAAAA
ACCTTTTCTCAAGCTGATCTGGATCAAAATGAATTTTCTATTGCTAGCCAACATTATGACTTTTTGCCACCTCTTATTAC
AGCTTTTTCGCAACAATACGATGGTCATCGTGTCTTTCGTATCTTTGAATCAACAACTATTCAAATTTTAGATGAGGGTG
CTCAAGGAAACAGTGAAATTGGTATTATTTACTTGAATGTAGACAATCAAAAAGGCCTCTTTCAGCGGATGGATAAGCTG
GGCTTGGAATATGTTTCTCTAATTCCTTTTACTACTCATATTTATCTTTCAAAAACGCATCCATTGGCTAATCGCGAAGC
GCTTTATTTGAGTGATATTCAAGGATTACCTGCGGTAAGGTTTACCCAAGAAGGGGACGAGTATTTGTATTATTCTGAAA
ATTTTGTGGATACTAGTGAATGCCCTCGTATTTATAATGTGTCAGATAGGGCAACCTTGAACGGTATTTTAGAGAGAACC
AATGCCTTTGCGACAGGATCAGGTTTTCTCGATCATCGGAGTGTTAATGGGATTAAAGTGATACCTCTAGCTGATCATAT
TGACAATCAAATGATTTATGTCAAACGAAAAGATAAAAACCTTTCTGTTGCTGGGGCCACTTTTGTGACTATTTTAAAAG
ACTATTTTGATAAAAGAAGGAAGGCCTTAACATGA

Upstream 100 bases:

>100_bases
TCTAATTGTAAAAAGTCAGCATAATAAAACAATGTCATAAGATGTTGTTATAACGGGCTTTATGGTATAATTAAGGATAC
TCATTTTAGGAAGGAAAGCA

Downstream 100 bases:

>100_bases
AAAAACGATTGTTTGTGCTTAGCTTGATCCTCCTTGTAGCTTTGGATCAACTTAGTAAATTTTGGATTGTTTCTCATATA
GCGCTTGGAGAAGTGAAACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEK
TFSQADLDQNEFSIASQHYDFLPPLITAFSQQYDGHRVFRIFESTTIQILDEGAQGNSEIGIIYLNVDNQKGLFQRMDKL
GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQEGDEYLYYSENFVDTSECPRIYNVSDRATLNGILERT
NAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRRKALT

Sequences:

>Translated_304_residues
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEK
TFSQADLDQNEFSIASQHYDFLPPLITAFSQQYDGHRVFRIFESTTIQILDEGAQGNSEIGIIYLNVDNQKGLFQRMDKL
GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQEGDEYLYYSENFVDTSECPRIYNVSDRATLNGILERT
NAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRRKALT
>Mature_304_residues
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEK
TFSQADLDQNEFSIASQHYDFLPPLITAFSQQYDGHRVFRIFESTTIQILDEGAQGNSEIGIIYLNVDNQKGLFQRMDKL
GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQEGDEYLYYSENFVDTSECPRIYNVSDRATLNGILERT
NAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRRKALT

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=305, Percent_Identity=24.9180327868852, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790399, Length=207, Percent_Identity=28.5024154589372, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787530, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=31.5068493150685, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=310, Percent_Identity=24.1935483870968, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788887, Length=309, Percent_Identity=22.3300970873786, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34412; Mature: 34412

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNRTTSGTVLTSQ
CCHHHEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHCHHEECCCCCCEEEECC
GLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFLPPLITAFSQQYDGHRVFR
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEE
IFESTTIQILDEGAQGNSEIGIIYLNVDNQKGLFQRMDKLGLEYVSLIPFTTHIYLSKTH
EECCCEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHCHHHEEECCEEEEEEEECCC
PLANREALYLSDIQGLPAVRFTQEGDEYLYYSENFVDTSECPRIYNVSDRATLNGILERT
CCCCCCEEEEECCCCCCCEEEECCCCCEEEEECCCCCHHHCCEEECCCCHHHHHHHHHHH
NAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRR
CCEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHH
KALT
HCCC
>Mature Secondary Structure
MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELGFQIFNRTTSGTVLTSQ
CCHHHEEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHCHHEECCCCCCEEEECC
GLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFLPPLITAFSQQYDGHRVFR
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEE
IFESTTIQILDEGAQGNSEIGIIYLNVDNQKGLFQRMDKLGLEYVSLIPFTTHIYLSKTH
EECCCEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHCHHHEEECCEEEEEEEECCC
PLANREALYLSDIQGLPAVRFTQEGDEYLYYSENFVDTSECPRIYNVSDRATLNGILERT
CCCCCCEEEEECCCCCCCEEEECCCCCEEEEECCCCCHHHCCEEECCCCHHHHHHHHHHH
NAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKRKDKNLSVAGATFVTILKDYFDKRR
CCEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHH
KALT
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]