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The map label for this gene is sagH [H]

Identifier: 94994047

GI number: 94994047

Start: 623594

End: 624721

Strand: Direct

Name: sagH [H]

Synonym: MGAS10750_Spy0651

Alternate gene names: 94994047

Gene position: 623594-624721 (Clockwise)

Preceding gene: 94994046

Following gene: 94994048

Centisome position: 32.19

GC content: 32.54

Gene sequence:

>1128_bases
ATGGTTTTATTTCATTTAATCAAAAAAGAAAGTTTACAGATTTTTAGAAACCGAACAGCCTTATTGATGATGGTGATTTT
TCCAATTTTGATGATCGTTATTTTAAGTTTTGCCTTTAAATCAAGTTTTAATACTGCGACAACAGTCCCTAAATTGACCA
TTCGTTACCAATTAGAGGGTGAAAAAACGGATTACCAGAAAAATTTTCTTGCTTTTTTAAAAGTTTTAAACCAAAAACTT
CATTTAGAGGCTAAACCTAGTAATTCTCTTGAAAAAGATCGACAAAGGGTCAGTGAAGGAGCCTTAACGGCTGTTTTAGA
AGTGAAGAAGAATCAGACCATTAAGGTTATTACTAATAATATTAATCAGCAAAATGCAGATTTAATCAATATGCTAGTAA
AAAATTATGTAGATAATGCTAAAACTTATGACTCGATAGCAGCTCTTTATCCTCAACAATTAAATCATATCAGAAAGCGA
AGTGTGGACTATGTTAAGGTCAGTTCAATACAGACAAGTAAAGGAATGACATCAGCTGATTATTATGCTATTTCCATGTT
TACCATGATTACTTTTTATAGTATGATGTCTGCGATGAACCTTGTTTTGTCAGATCGTCAACAACGGATTACAAATCGTA
TTCGCTTAACAGGAGTTTCTCCAAGTCTTTTAGTCTTTGGGAAATTAATAGGTGCTATGTTAGCAACAACTGTTCAATTG
AGTCTTTTATACATTTTTACAAGGTTTGTTTTACGAGTTAATTGGGGCACTAATGAGTGGATGCTTATTGGTATAACAGC
CTCCTTAGTCTATCTCTCTGTAGCTATAGGTATCGGGCTAGGCATAAGCATTAAAAATGAGGCTTTTTTAACGGTTGCAT
CCAATACTATTATTCCTATATTCGCCTTTTTAGGAGGCAGTTACGTTCCATTGACAACATTACACAGCTCTATTATTAAT
CAATTGTCGAATATATCTCCTATTAAATGGGTTAATGATAGTTTGTTCTATCTTATTTTTGGTGGTCAATATAATCCGAT
TCCTGTAACTTTGATCGTTAATATTAGTATCGGAACAATTTTTATAATATTGGCATTAATAGGTATGAGAAAGCAGGTGA
CGACATGA

Upstream 100 bases:

>100_bases
AGGCCAATATTACTTTTAGCGAGATTAGACATAACCATTTGAATTTAGAAGAAATTTTCTTACACTTAACAGGTAAGAAG
TTACGAGATTAGAGGTTACT

Downstream 100 bases:

>100_bases
TTTGTTTTATAAAAACTCTATTTGTTAAGATAAAGCGCAAAAAAACAAGTTATGTGACATTCTTTTTAATGCCTATTTTA
ACGACACTTTTGGCTTTATC

Product: streptolysin S export transmembrane protein SagH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKL
HLEAKPSNSLEKDRQRVSEGALTAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTGVSPSLLVFGKLIGAMLATTVQL
SLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIIN
QLSNISPIKWVNDSLFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT

Sequences:

>Translated_375_residues
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKL
HLEAKPSNSLEKDRQRVSEGALTAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTGVSPSLLVFGKLIGAMLATTVQL
SLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIIN
QLSNISPIKWVNDSLFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT
>Mature_375_residues
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKL
HLEAKPSNSLEKDRQRVSEGALTAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTGVSPSLLVFGKLIGAMLATTVQL
SLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIIN
QLSNISPIKWVNDSLFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT

Specific function: Unknown

COG id: COG0842

COG function: function code V; ABC-type multidrug transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000412
- InterPro:   IPR013525 [H]

Pfam domain/function: PF01061 ABC2_membrane [H]

EC number: NA

Molecular weight: Translated: 42149; Mature: 42149

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVPKLTIRYQLEG
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
EKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGALTAVLEVKKNQTIKVITNN
CCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEECC
INQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKRSVDYVKVSSIQTSKGMTSAD
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECEECCCCCCCHH
YYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTGVSPSLLVFGKLIGAMLATTVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHH
SLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPI
HHHHHHHHHHEEEECCCCCEEEEEHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCHHHH
FAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDSLFYLIFGGQYNPIPVTLIVNISIGTI
HHHHCCCCCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCEEEEEEEEEHHHHH
FIILALIGMRKQVTT
HHHHHHHHCHHHCCC
>Mature Secondary Structure
MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFNTATTVPKLTIRYQLEG
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECC
EKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGALTAVLEVKKNQTIKVITNN
CCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEECC
INQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKRSVDYVKVSSIQTSKGMTSAD
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECEECCCCCCCHH
YYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTGVSPSLLVFGKLIGAMLATTVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHH
SLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAIGIGLGISIKNEAFLTVASNTIIPI
HHHHHHHHHHEEEECCCCCEEEEEHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCHHHH
FAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDSLFYLIFGGQYNPIPVTLIVNISIGTI
HHHHCCCCCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCEEEEEEEEEHHHHH
FIILALIGMRKQVTT
HHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]