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The map label for this gene is lytG [H]

Identifier: 94994016

GI number: 94994016

Start: 586638

End: 587843

Strand: Direct

Name: lytG [H]

Synonym: MGAS10750_Spy0620

Alternate gene names: 94994016

Gene position: 586638-587843 (Clockwise)

Preceding gene: 94994015

Following gene: 94994019

Centisome position: 30.28

GC content: 44.61

Gene sequence:

>1206_bases
ATGACCTTTTTAGATAAAATTAAACAAGGCTGTTTAGATGGCTGGGCTAAGTACAAAATCTTGCCATCCTTGACCGCAGC
ACAAGCTATCTTAGAGAGCGGGTGGGGTAAACATGCACCACATAACGCTTTGTTTGGTATTAAGGCAGACGCAAGCTGGA
CCGGTAAGTCGTTTAACACCAAAACCCAAGAGGAATATCAAGCTGGTGTTATTACTGACATTGTTGACAGGTTTAGAGCC
TATGACAGCTGGGATGAATCTATCGCTGACCATGGACAATTTTTAGTAGATAATCCACGCTACCAGTCTGTTATTGGGGA
GGCTGATTATAAAAAAGCTTGTCATGCTATAAAAGATGCAGGCTATGCGACTGCGAGTGGCTATGCGGAGCTACTTATCC
AAATTATTGAGGAGAATAACTTGCAGAAATGGGATAAAGAGGCTATTGTCAGAAAGGAGAAGCAAATGATTAATTCTCAA
TGTCGAGAAGTCATTGAATTTTTTATTAATTTGGCCAATGCTGGTATGGGTGTTGACAAAGATAGTTTTGCGGGCTGGCA
ATGTGCAGATGTGCCTTGTTATGCAGCAAAGCACTGGTTCGATGTCGACCTTTGGGGAAATGCGATTGACTTACTAGATA
GCGCTGCTGCCGTAGGTTGGGAAGTCCATCGCATGCCGACAGATGCAAATCCACTGACGGGAGCATTTTTTGTCCAATCA
GTGCCGTATCACCAATTTGGACATACGGGAATTGTTATCGAGGATAGTGACGGTTACACCATGCGCACTGTCGAGCAAAA
CATTGATGGCAATCCTGATGCTTTGTATGTCGGTGCACCAGCTCGTTTTAACACTCGTGACTTTACTGGCGTGATAGGTT
GGTTTTACCCACCATATCAAGGGGATACAGTCACGCAACCAGTCAGCACCGAGCCGCAAACTTCTGAAACGATCGTGGAG
ACAGCAAAAACAGGCACCTTTACCCTTGATGTTGCAGAGATCAATATCAGACGCTGGCCAAGCCTAGCCAGTGAAGTAGT
AGGTAGCTATAAGCAAGGTGATACTGTCAGCTTTGACAATGAGGGTTATGCCAACGGTTACTACTGGATTAGCTATGTTG
GCGGCTCAGGTATGCGTAACTACCTAGGTATTGGACAGACTGATAAAGATGGGAATCGCATCAGCCTTTGGGGTAAATTA
AATTAG

Upstream 100 bases:

>100_bases
CAATCACACGATTAGCATTAGTTATAGCAATCGCAATACTGTATGTGCCATTATCTGTGGTTGCTCTTATCTTTTATCCG
TTTTTAGATAAGGAGGACAG

Downstream 100 bases:

>100_bases
GAGGTAAAGCTCCGAGATAAGACAAAACCGCTCAGATTATTCTGGGCGGTTTTTTGTGTATGATGAATTATTTTTCAAGA
TAAATATCGAAATGACTAAA

Product: phage-associated cell wall hydrolase

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTFLDKIKQGCLDGWAKYKILPSLTAAQAILESGWGKHAPHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIVDRFRA
YDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQIIEENNLQKWDKEAIVRKEKQMINSQ
CREVIEFFINLANAGMGVDKDSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAAVGWEVHRMPTDANPLTGAFFVQS
VPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVIGWFYPPYQGDTVTQPVSTEPQTSETIVE
TAKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVSFDNEGYANGYYWISYVGGSGMRNYLGIGQTDKDGNRISLWGKL
N

Sequences:

>Translated_401_residues
MTFLDKIKQGCLDGWAKYKILPSLTAAQAILESGWGKHAPHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIVDRFRA
YDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQIIEENNLQKWDKEAIVRKEKQMINSQ
CREVIEFFINLANAGMGVDKDSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAAVGWEVHRMPTDANPLTGAFFVQS
VPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVIGWFYPPYQGDTVTQPVSTEPQTSETIVE
TAKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVSFDNEGYANGYYWISYVGGSGMRNYLGIGQTDKDGNRISLWGKL
N
>Mature_400_residues
TFLDKIKQGCLDGWAKYKILPSLTAAQAILESGWGKHAPHNALFGIKADASWTGKSFNTKTQEEYQAGVITDIVDRFRAY
DSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDAGYATASGYAELLIQIIEENNLQKWDKEAIVRKEKQMINSQC
REVIEFFINLANAGMGVDKDSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAAVGWEVHRMPTDANPLTGAFFVQSV
PYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVIGWFYPPYQGDTVTQPVSTEPQTSETIVET
AKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVSFDNEGYANGYYWISYVGGSGMRNYLGIGQTDKDGNRISLWGKLN

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=122, Percent_Identity=37.7049180327869, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 44570; Mature: 44439

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLDKIKQGCLDGWAKYKILPSLTAAQAILESGWGKHAPHNALFGIKADASWTGKSFNT
CCHHHHHHHHHHCCHHHEEECCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
KTQEEYQAGVITDIVDRFRAYDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEECCCHHHHHHCCCHHHHHHHHHHHC
GYATASGYAELLIQIIEENNLQKWDKEAIVRKEKQMINSQCREVIEFFINLANAGMGVDK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAAVGWEVHRMPTDANPLTGAFFVQS
CCCCCCEECCCCHHHHCCEEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHCC
VPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVIGWFYPPYQ
CCHHHCCCEEEEEECCCCCEEEEEHHCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCC
GDTVTQPVSTEPQTSETIVETAKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVSFDN
CCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEEECHHHCHHHHHHHHCCCCCCCEEEECC
EGYANGYYWISYVGGSGMRNYLGIGQTDKDGNRISLWGKLN
CCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TFLDKIKQGCLDGWAKYKILPSLTAAQAILESGWGKHAPHNALFGIKADASWTGKSFNT
CHHHHHHHHHHCCHHHEEECCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCC
KTQEEYQAGVITDIVDRFRAYDSWDESIADHGQFLVDNPRYQSVIGEADYKKACHAIKDA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEECCCHHHHHHCCCHHHHHHHHHHHC
GYATASGYAELLIQIIEENNLQKWDKEAIVRKEKQMINSQCREVIEFFINLANAGMGVDK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAAVGWEVHRMPTDANPLTGAFFVQS
CCCCCCEECCCCHHHHCCEEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHCC
VPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNTRDFTGVIGWFYPPYQ
CCHHHCCCEEEEEECCCCCEEEEEHHCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCC
GDTVTQPVSTEPQTSETIVETAKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVSFDN
CCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEEECHHHCHHHHHHHHCCCCCCCEEEECC
EGYANGYYWISYVGGSGMRNYLGIGQTDKDGNRISLWGKLN
CCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]