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The map label for this gene is yrrO [H]

Identifier: 94993907

GI number: 94993907

Start: 492604

End: 493890

Strand: Direct

Name: yrrO [H]

Synonym: MGAS10750_Spy0511

Alternate gene names: 94993907

Gene position: 492604-493890 (Clockwise)

Preceding gene: 94993906

Following gene: 94993908

Centisome position: 25.43

GC content: 44.37

Gene sequence:

>1287_bases
ATGTCACATATGAAAAAACGTCCCGAGGTCTTATCACCTGCTGGAACACTTGAAAAATTAAAAGTTGCGATTGACTATGG
CGCAGATGCTGTTTTTGTTGGAGGACAGGCCTATGGCCTAAGAAGCCGCGCTGGTAACTTCTCTATGGAAGAATTGCAAG
AAGGCATTGATTATGCACATGCGCGTGGAGCTAAGGTTTATGTTGCTGCCAACATGGTTACCCACGAAGGGAACGAAATT
GGTGCGGGCGAGTGGTTTCGTCAACTGCGTGATATGGGGCTTGATGCGGTCATTGTTTCAGATCCAGCCTTGATTGTTAT
TTGTTCAACAGAAGCCCCAGGTTTGGAAATTCATTTGTCAACGCAAGCTTCATCTACCAATTACGAGACCTTTGAATTTT
GGAAAGCCATGGGTTTGACGCGTGTTGTTTTAGCTCGCGAGGTTAATATGGCCGAGTTAGCAGAAATCCGTAAGCGGACA
GATGTGGAAATTGAAGCCTTTGTCCATGGAGCCATGTGTATTTCTTATTCAGGCCGCTGTGTTTTGTCAAACCACATGAG
TCACCGTGATGCCAACAGGGGCGGCTGCTCACAGTCTTGCCGCTGGAAGTATGATTTGTATGACATGCCATTTGGAGGAG
AGCGCCGCTCCTTAAAAGGGGAAATTCCAGAAGACTATTCTATGTCCTCTGTTGACATGTGTATGATTGACCATATTCCT
GACCTGATTGAAAATGGAGTTGATAGCTTAAAAATTGAAGGCCGAATGAAATCTATCCACTACGTCTCAACCGTAACCAA
CTGTTACAAGGCGGCTGTAGATGCTTACATGGAAAGCCTAGAAGCTTTTTATGCTATCAAAGAGGAATTGATTGACGAGT
TGTGGAAGGTTGCCCAGCGCGAGTTAGCTACAGGTTTTTACTATGGTATCCCAACTGAAAATGAACAATTATTTGGTGCT
CGCCGCAAAATTCCACAATATAAATTTGTCGGAGAAGTAGTTGCCTTTGACTCAGCTAGCATGACAGCGACCATTCGTCA
GCGTAATGTCATCATGGAAGGCGATCGGATTGAATGTTATGGACCAGGTTTCCGTCATTTTGAAACGGTTGTTAAGGACT
TACATGATGCGGATGGCCAAAAGATTGATCGTGCCCCAAATCCAATGGAACTCTTAACCATTTCTTTGCCAAGAGAGGTT
AAACCAGGAGATATGATTAGGGCTTGCAAGGAAGGTCTGGTTAACCTCTATCAAAAAGACGGTACAAGTAAAACTGTCAG
AGCTTAA

Upstream 100 bases:

>100_bases
TAATCCTTGTCTTGAGTGAGTTTACTATTTCAGGGCAAGACAGGGTTATGACACCATTACACAGGTAATCTACCTATCTT
GAAAATAGAAAGAATATCAC

Downstream 100 bases:

>100_bases
TTGAAATAAATATGAAAGGCCCTTTTTCCCTAGTGGCGTAAAAGCTGCGTTTGGGATAAAAGAGCCGGTTTTTTGAAAAT
TAGATACCACGATAGCTTAT

Product: Peptidase family U32

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEI
GAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAYMESLEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGA
RRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREV
KPGDMIRACKEGLVNLYQKDGTSKTVRA

Sequences:

>Translated_428_residues
MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEI
GAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAYMESLEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGA
RRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREV
KPGDMIRACKEGLVNLYQKDGTSKTVRA
>Mature_427_residues
SHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIG
AGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRTD
VEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIPD
LIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAYMESLEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGAR
RKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREVK
PGDMIRACKEGLVNLYQKDGTSKTVRA

Specific function: Unknown

COG id: COG0826

COG function: function code O; Collagenase and related proteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U32 family [H]

Homologues:

Organism=Escherichia coli, GI1788397, Length=437, Percent_Identity=33.6384439359268, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI87081910, Length=280, Percent_Identity=37.5, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789548, Length=300, Percent_Identity=32, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001539 [H]

Pfam domain/function: PF01136 Peptidase_U32 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 47899; Mature: 47768

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS01276 PEPTIDASE_U32

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAH
CCCCCCCCCCCCCCCCHHHEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
ARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLS
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCEEEEEE
TQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRTDVEIEAFVHGAMCISYSGRC
CCCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCEEEHHEEEEEEEECCCCE
VLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
EEECCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAYMESLEAFYAIKEELIDELWKVAQR
HHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELATGFYYGIPTENEQLFGARRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECY
HHHCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEHHCCEEEECCEEEEE
GPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREVKPGDMIRACKEGLVNLYQKD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
GTSKTVRA
CCCCCCCC
>Mature Secondary Structure 
SHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAH
CCCCCCCCCCCCCCCHHHEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
ARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLS
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCEEEEEE
TQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRTDVEIEAFVHGAMCISYSGRC
CCCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCEEEHHEEEEEEEECCCCE
VLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
EEECCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAYMESLEAFYAIKEELIDELWKVAQR
HHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELATGFYYGIPTENEQLFGARRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECY
HHHCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEHHCCEEEECCEEEEE
GPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREVKPGDMIRACKEGLVNLYQKD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
GTSKTVRA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]