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The map label for this gene is lgt [H]

Identifier: 94993902

GI number: 94993902

Start: 489303

End: 490082

Strand: Direct

Name: lgt [H]

Synonym: MGAS10750_Spy0506

Alternate gene names: 94993902

Gene position: 489303-490082 (Clockwise)

Preceding gene: 162139189

Following gene: 94993903

Centisome position: 25.26

GC content: 36.54

Gene sequence:

>780_bases
ATGATCAATCCCATTGCCTTAAAATGTGGTCCACTAGCCATCCACTGGTATGCTCTATGTATCTTGTCAGGACTTGTTTT
GGCGGTTTACTTAGCATCAAAAGAAGCACCCAAAAAAGGAATATCATCTGACGCTATTTTCGATTTTATTCTGATTGCTT
TTCCACTTGCTATTGTTGGTGCAAGAATTTACTATGTTATTTTTGAATGGTCTTATTATGTCAAGCATTTAGATGAAATC
ATAGCCATTTGGAATGGCGGTATTGCTATTTATGGCGGTCTCATTACAGGAGCTCTTGTACTTTTGGCTTACTGTTATAA
CAAGGTGCTCAATCCCATTCATTTTTTAGATATTGCCGCACCAAGTGTCATGGTCGCTCAAGCTATCGGTCGCTGGGGAA
ATTTTATCAACCAAGAAGCCTATGGTAAAGCTGTGAGCCAGTTAAATTACTTACCAAGCTTTATTCAAAAGCAAATGTTT
ATAGAGGGAAGTTACCGCATTCCGACCTTTCTCTATGAATCATTTTGGAATCTTTTGGGATTTGTCATTATTATGATGTG
GCGTCGTAAGCCAAAAAGCCTATTAGATGGAGAAATCTTTGCATTTTACTTAATTTGGTATGGTAGTGGAAGGCTAGTCA
TTGAAGGTATGCGAACAGATAGTCTTATGTTTTTAGGTATTCGCATCTCCCAATATGTGTCTGCCTTATTAATTATTATT
GGCTTAATCTTTGTTATAAAAAGACGTCGTCAAAAAGGAATTTCTTATTATCAAGAATAA

Upstream 100 bases:

>100_bases
CCGCTGCGATGAATCATCGGGCTAAAGAAATGGGCTTTGATGCTACAAAAACTTTTGAAGATCGTTTAACTCAACTAATC
ACCAAAAATGAGGTGAGTCA

Downstream 100 bases:

>100_bases
GGATAGAAAAAGGAGAAACTTATGGACTTAGTTGGAATCTCACTGATGATTATTGCACTCGCATTTGTTGCTTTGGTGAT
TTTCTTGATTATTGTATTAA

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEI
IAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
IEGSYRIPTFLYESFWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIII
GLIFVIKRRRQKGISYYQE

Sequences:

>Translated_259_residues
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEI
IAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
IEGSYRIPTFLYESFWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIII
GLIFVIKRRRQKGISYYQE
>Mature_259_residues
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEI
IAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
IEGSYRIPTFLYESFWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIII
GLIFVIKRRRQKGISYYQE

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins [H]

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family [H]

Homologues:

Organism=Escherichia coli, GI1789192, Length=283, Percent_Identity=26.8551236749117, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001640 [H]

Pfam domain/function: PF01790 LGT [H]

EC number: 2.4.99.- [C]

Molecular weight: Translated: 29455; Mature: 29455

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]