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The map label for this gene is yhfT [H]

Identifier: 94993849

GI number: 94993849

Start: 440587

End: 441834

Strand: Direct

Name: yhfT [H]

Synonym: MGAS10750_Spy0453

Alternate gene names: 94993849

Gene position: 440587-441834 (Clockwise)

Preceding gene: 94993848

Following gene: 94993850

Centisome position: 22.74

GC content: 37.1

Gene sequence:

>1248_bases
ATGCTGACAAAGCTAGAATATTGGGCAAAGCAATGCCCAAATAAAAAAGCTATCGTAGCCGATCAGATAAGCTTGACTTA
TCAAGAGCTATGGCAAGCGGTTCTAATAAAGGATCAGACAATAAAAGACAGTGTACCATATATCATCAGTCATAGTCGCT
ATCTTAATCAGTTACTCTCTTTTTTACGAGGATTAAAAGAAGGCAGTTGTCCTATCATTTTACACCCTAATATCTCAGGT
ACATTTCAGCAGCAAATAAAACACGTCGATAGTGAGCTTCTTAAAAAAGCTGATTTTGCTGTTTTGAGTTCGGGAACAAC
TGGCAAAGCAAAATTATTTTGGCGTTGTCTATCAACTTGGACGAGACTTTTTGATTATCAAAATAAGGTGTTTGGTATGA
CTGGTAATAGTTGTCTATTCTTACATGGTAGTTTTAGTTTTACTGGCAATCTTAACTTAGCATTAGCTCAACTATGGGCC
GGGGGATGTCTGGTTTTAAGCCAAAAGCTGTCTTTGAAAACGTGGTTAAGCTTATGGCAAGCAAAAAAGGTGAGTCACCT
TTACCTTTTACCGACTTACCTAAATCGCTTGCTACCTTATTTGACTAAGAACAACATGACTGCGACTCACTTATTGACCT
CTTCGCAAATGATATCACAAGAATTACTAAGACATTATTACAAAAAATTTCCTCAGCTTGAAATTGTCATTTTCTACGGG
GCTAGTGAATTATCTTTTATAACGTGGTGTAATGGCAGAGCTGCTGTCAAAATTAATGGTTTGGTAGGACAGCCCTTTCC
TGATGTGTCTATCAGTTTCAAAGATAAGGAAATTTTTGTAGAGACTCCTTATAGTGTAGAAGGAATGTCACAACCATACA
GTGTCTCAGACTTAGGAAAAATGAGCCCAGCGGGTTTAATTTTAGAAGGGCGACAAGATGACTGGGTTAATCAACGAGGA
GTGAAATGCCACCTGCCTAGCCTAGTTGAACTCGCTCACCAAGCGCCAAACGTCAAAGAAGCACACGCTTTAAAGATAGG
AAAAGGAGAAAACGAAACCCTAATATTAGTATTAGTTTTGACTAAGAAGGATTGCCTAGCACCTATTAAAGACTTTTTAG
CTCTTTATTTAAACTCTGGACAACTTCCTAAGTACTATCTTGTGATTGATTGTTTGCCTTTAAAAGATAATGGTAAAATT
AATCAAGAAGTTCTTTTAAATAAAATACCCAAACAGTGGCTTAGTTAA

Upstream 100 bases:

>100_bases
CTTTAGAGATCAAAAATGGACGCTATGGAATAGCTGCTATAGCAGCAGCTGGTGGCCAAGGGTTTGCTGTTTTACTAAAA
TAATCATAAGGAGTTTAGTC

Downstream 100 bases:

>100_bases
CGATTTCAGGTTTCGTTTTGCTTATAGTGAGATACAAGTGACGATTCAGCTTTAGATGTGTTATAATATGGTCAAAAAAG
ATGAGGAGAAGGCCATGAAA

Product: Long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDSVPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISG
TFQQQIKHVDSELLKKADFAVLSSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMISQELLRHYYKKFPQLEIVIFYG
ASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDKEIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRG
VKCHLPSLVELAHQAPNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCLPLKDNGKI
NQEVLLNKIPKQWLS

Sequences:

>Translated_415_residues
MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDSVPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISG
TFQQQIKHVDSELLKKADFAVLSSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMISQELLRHYYKKFPQLEIVIFYG
ASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDKEIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRG
VKCHLPSLVELAHQAPNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCLPLKDNGKI
NQEVLLNKIPKQWLS
>Mature_415_residues
MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDSVPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISG
TFQQQIKHVDSELLKKADFAVLSSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMISQELLRHYYKKFPQLEIVIFYG
ASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDKEIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRG
VKCHLPSLVELAHQAPNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCLPLKDNGKI
NQEVLLNKIPKQWLS

Specific function: May be involved in fatty acid metabolism [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 46916; Mature: 46916

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDSVPYIISHSRYLNQLLS
CCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHH
FLRGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFAVLSSGTTGKAKLFWRCLSTW
HHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
TRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWAGGCLVLSQKLSLKTWLSLWQ
HHHHHHCCCEEECCCCCEEEEEECEEEECCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
AKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMISQELLRHYYKKFPQLEIVIFYG
HHCCCEEEEEHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
ASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDKEIFVETPYSVEGMSQPYSVSDLGK
CCCEEEEEEECCEEEEEECCCCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCCHHHHCC
MSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQAPNVKEAHALKIGKGENETLILVLVL
CCCCCEEEECCCCCCCCCCCCEEECCHHHHHHHHCCCCCHHHEEEECCCCCCEEEEEEEE
TKKDCLAPIKDFLALYLNSGQLPKYYLVIDCLPLKDNGKINQEVLLNKIPKQWLS
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDSVPYIISHSRYLNQLLS
CCCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHH
FLRGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFAVLSSGTTGKAKLFWRCLSTW
HHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHH
TRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWAGGCLVLSQKLSLKTWLSLWQ
HHHHHHCCCEEECCCCCEEEEEECEEEECCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHH
AKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMISQELLRHYYKKFPQLEIVIFYG
HHCCCEEEEEHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
ASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDKEIFVETPYSVEGMSQPYSVSDLGK
CCCEEEEEEECCEEEEEECCCCCCCCCCCEEEEECCEEEEECCCCCCCCCCCCCHHHHCC
MSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQAPNVKEAHALKIGKGENETLILVLVL
CCCCCEEEECCCCCCCCCCCCEEECCHHHHHHHHCCCCCHHHEEEECCCCCCEEEEEEEE
TKKDCLAPIKDFLALYLNSGQLPKYYLVIDCLPLKDNGKINQEVLLNKIPKQWLS
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]