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The map label for this gene is frr [H]

Identifier: 94993775

GI number: 94993775

Start: 381515

End: 382072

Strand: Direct

Name: frr [H]

Synonym: MGAS10750_Spy0379

Alternate gene names: 94993775

Gene position: 381515-382072 (Clockwise)

Preceding gene: 94993774

Following gene: 94993776

Centisome position: 19.7

GC content: 39.78

Gene sequence:

>558_bases
ATGGCAAATGCAATTATTGAAACTGCAAAAGAACGTTTTGCACAATCCCATCAGTCTTTATCACGTGAATATGCCAGCAT
TCGTGCGGGTCGTGCCAACGCTAGTCTTTTAGACCGTATCCAAGTTGATTATTACGGGGCACCGACGCCATTAAATCAAT
TGGCTTCAATCACTGTACCAGAAGCGCGTGTCTTATTGATCTCGCCTTTTGATAAATCTTCTATCAAAGATATCGAGCGT
GCTCTTAACGCATCAGATTTAGGCATTACACCTGCTAACGATGGCTCTGTCATTCGTTTGGTTATTCCAGCTTTGACCGA
AGAAACACGTAAAGAATTAGCCAAAGAAGTGAAAAAAGTTGGTGAAAATGCTAAAATTGCAATCCGTAATATCCGCCGTG
ATGCTATGGATGATGCTAAAAAGCAAGAAAAAGCAAAAGAAATCACTGAAGATGAGTTAAAAACACTTGAGAAAGATATC
CAAAAAGCAACCGATGATGCTATCAAAGAAATTGACCGCATGACGGCTGAAAAAGAAAAAGAATTGCTCTCAGTGTAA

Upstream 100 bases:

>100_bases
GCTGGCAATATTCAACGTGTTGTCTTTGGAGAACATATTGGAACTACTGTATCAAATAAAGTTTGTGACTAAAAGTTAGA
AAAGAAAGAGAGTAATTATC

Downstream 100 bases:

>100_bases
CAGGATTCCTACGAAAAATAGACGACTATAGACACAAAAAGATAGGTGACCATTTCAGAAGCGTTTGGTTTTGATTTGTC
CCTATTTTTTTAAAGAAAGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIER
ALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
QKATDDAIKEIDRMTAEKEKELLSV

Sequences:

>Translated_185_residues
MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIER
ALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
QKATDDAIKEIDRMTAEKEKELLSV
>Mature_184_residues
ANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERA
LNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQ
KATDDAIKEIDRMTAEKEKELLSV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI291042689, Length=183, Percent_Identity=29.5081967213115, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20270317, Length=156, Percent_Identity=31.4102564102564, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=47.5409836065574, Blast_Score=157, Evalue=3e-40,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20573; Mature: 20441

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
EARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKV
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLSV
HHHCC
>Mature Secondary Structure 
ANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCC
EARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKV
CCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLSV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA