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The map label for this gene is nrdF [H]

Identifier: 94993745

GI number: 94993745

Start: 354574

End: 355587

Strand: Direct

Name: nrdF [H]

Synonym: MGAS10750_Spy0349

Alternate gene names: 94993745

Gene position: 354574-355587 (Clockwise)

Preceding gene: 94993744

Following gene: 94993746

Centisome position: 18.3

GC content: 43.1

Gene sequence:

>1014_bases
ATGACCCAATATTATTATGAACGTTCGCAATCCCCAATTGAATACGCCCTATCTGAAACACAAAAACAGTTGCGCTCCAT
CAATTGGAATTACCTTAATGATGACAAAGATTTGGAAGTGTGGAACCGTGTCACTCAAAATTTTTGGTTGCCTGAAAAGG
TTCCTGTTTCTAATGATTTAAATTCTTGGCGCTCCTTGGGTGAGGATTGGCAACAGCTCATCACAAGGACCTACACTGGG
TTGACCTTACTAGATACAGTACAAGCAACGGTTGGTGATGTGGCACAAATTCAGCATTCACAAACCGACCACGAACAAGT
CATCTATACGAACTTTGCCTTTATGGTGGGGATTCATGCCCGCTCTTACGGGACGATTTTTTCGACCCTTTGCAGCAGTG
AGCAAATCGAAGAAGCACATGAATGGGTGGTCTCAACACAGAGCTTGCAAGACCGTGCCCGTGTCTTGATTCCTTACTAT
ACGGGTGATGACCCTTTGAAATCAAAAGTAGCAGCAGCTATGATGCCAGGATTTTTGCTGTATGGCGGCTTTTACCTTCC
TTTTTACCTATCAGCACGTGGTAAAATGCCAAACACCTCTGATATCATCCGTCTGATTTTACGCGACAAAGTTATTCACA
ACTATTACAGCGGTTACAAATACCAACAAAAAGTAGCACGTCTTAGCCCAGAAAAACAGGCTGAAATGAAGGCCTTTGTC
TTTGACTTGCTCTATGAACTCATCGACCTTGAAAAAGCTTACTTGAGAGAACTGTATGCAGGCTTTGATTTGGCAGAAGA
TGCTATCCGCTTTAGCCTTTATAACGCTGGAAAATTCCTTCAAAATTTGGGATATGAGTCGCCATTTACAGAAGAAGAAA
CGCGCGTTTCACCAGAAGTATTTGCTCAGCTATCAGCGCGTGCAGACGAAAACCATGACTTTTTCTCAGGCAATGGCTCA
TCTTATGTGATGGGGATCACCGAAGAAACCACAGATGACGATTGGGAGTTTTAA

Upstream 100 bases:

>100_bases
TCAAAAAAACAGTTCCTGTCTGTTTGGCGTCTAGTGATGACTTAGGCTTAGCGCTACTAGACTTTTGTTTGAAAAATACC
TCAAGCCTTGAAGGAGACAA

Downstream 100 bases:

>100_bases
GAAATGGCAGAGCTGATTATTGTGTATTTTTCATCTAAGTCCAATAACACCCATCGCTTCGTCCAAAAATTAGGCCTGCC
TGCTCAGCGCATACCAGTAG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTQYYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTG
LTLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFV
FDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYESPFTEEETRVSPEVFAQLSARADENHDFFSGNGS
SYVMGITEETTDDDWEF

Sequences:

>Translated_337_residues
MTQYYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTG
LTLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFV
FDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYESPFTEEETRVSPEVFAQLSARADENHDFFSGNGS
SYVMGITEETTDDDWEF
>Mature_336_residues
TQYYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGL
TLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYYT
GDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFVF
DLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYESPFTEEETRVSPEVFAQLSARADENHDFFSGNGSS
YVMGITEETTDDDWEF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1789031, Length=315, Percent_Identity=51.7460317460318, Blast_Score=351, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 39053; Mature: 38922

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDL
CCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
NSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHEEHH
RSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYYTGDDPLKSKVAAAMMPGFLL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
YGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFV
HHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHH
FDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYESPFTEEETRVSPEV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHH
FAQLSARADENHDFFSGNGSSYVMGITEETTDDDWEF
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TQYYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRVTQNFWLPEKVPVSNDL
CCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCH
NSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQTDHEQVIYTNFAFMVGIHA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHEEHH
RSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYYTGDDPLKSKVAAAMMPGFLL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
YGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSGYKYQQKVARLSPEKQAEMKAFV
HHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHH
FDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNAGKFLQNLGYESPFTEEETRVSPEV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHH
FAQLSARADENHDFFSGNGSSYVMGITEETTDDDWEF
HHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]