Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 94993694

GI number: 94993694

Start: 311760

End: 312785

Strand: Direct

Name: yggV [C]

Synonym: MGAS10750_Spy0298

Alternate gene names: 94993694

Gene position: 311760-312785 (Clockwise)

Preceding gene: 94993693

Following gene: 94993695

Centisome position: 16.09

GC content: 41.62

Gene sequence:

>1026_bases
TTGGCTGAAACAAAAAATAAATGTGGAGCATGTCACCTTATGAGTGAAAAAATTTACGAATACAAAGATGAAAATAACTG
GTTTATCGGAAAGATGACTGGTCATAATTTAATATCGGGCTGGGGAGTCAAACACACGACAATCAAAAAAATAGATGACC
TTTTAGACGGTATTGCCGCAACGTTAGATTGGGAAAATCCTAAAGGTTACGATGTTTCGGTGGTGCGTTATCAGTCTCCT
TTATCTCTCATCACCTTTATTATCGACATGATAAATCAAGAGACCCAGCGTAAGATTAAGGTAACTCCCCATGCAGGCAC
GATTTTATTAATGGAAAATGCGAAACTGCTTGCAGTTTATCTCCCAGAAGGTGGAGTTTCAACGGCTACATTTTTTGCGA
CTAGTGAACAGGGATTTGGGGATATTATTTTAATCGCTACACGAAACGAGGGAAAAACCAAAGAGTTCCGCAATCTGTTT
GGCCAGCTAGGTTATCGTGTGGAAAATCTCAATGATTATCCAGAATTGCCAGAAGTAGCAGAAACTGGTACTACTTTTGA
AGAAAATGCTCGCTTGAAAGCAGAAACGATTTCACGCCTCACAGGAAAAATGGTATTAGCAGACGATTCAGGACTAAAAG
TTGATGCCTTGGGTGGTTTACCTGGTGTTTGGTCAGCTCGTTTCTCAGGACCAGATGCCACAGATGCCAAGAATAATGCC
AAACTCTTACACGAATTAGCTATGGTGTTTGACCAAAAGAAGCGCTCAGCTCAATTTCATACGACTTTAGTAGTGGCTGC
TCCCAATAAAGATAGTTTGGTTGTGGAAGCCGAGTGGCCAGGCTATATTGCTACGCAGCCTAAGGGAGAAAATGGTTTTG
GGTATGATCCTGTCTTTATCGTCGGAGAGACTGGGCGTCATGCTGCAGAATTAGAGGCTGACCAAAAAAATCAGTTGTCG
CATAGAGGTCAAGCAGTTCGAAAATTAATGGAGGTCTTTCCAGCATGGCAAGCAAAACAATCATAG

Upstream 100 bases:

>100_bases
TAAACTATTTTGACATTAACGGTAACTATCATCAAAAAGCTGTCGAACACCGCTTTTTTACAACAGCAAATTCTGAGATT
TTTCAAGAAATTGCCTCGAT

Downstream 100 bases:

>100_bases
TAATGAGTGACTCTCATGGTGACCGAGATATCGTTCAAGCCATTAAAGATAAGTATCTTGGTCAAGTTGATGCTATTTTC
CATAATGGGGATTCTGAATT

Product: deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAETKNKCGACHLMSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAATLDWENPKGYDVSVVRYQSP
LSLITFIIDMINQETQRKIKVTPHAGTILLMENAKLLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLF
GQLGYRVENLNDYPELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGPDATDAKNNA
KLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKGENGFGYDPVFIVGETGRHAAELEADQKNQLS
HRGQAVRKLMEVFPAWQAKQS

Sequences:

>Translated_341_residues
MAETKNKCGACHLMSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAATLDWENPKGYDVSVVRYQSP
LSLITFIIDMINQETQRKIKVTPHAGTILLMENAKLLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLF
GQLGYRVENLNDYPELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGPDATDAKNNA
KLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKGENGFGYDPVFIVGETGRHAAELEADQKNQLS
HRGQAVRKLMEVFPAWQAKQS
>Mature_340_residues
AETKNKCGACHLMSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAATLDWENPKGYDVSVVRYQSPL
SLITFIIDMINQETQRKIKVTPHAGTILLMENAKLLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFG
QLGYRVENLNDYPELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGPDATDAKNNAK
LLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKGENGFGYDPVFIVGETGRHAAELEADQKNQLSH
RGQAVRKLMEVFPAWQAKQS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=44.559585492228, Blast_Score=157, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 37738; Mature: 37607

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETKNKCGACHLMSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAA
CCCCCCCCCEEEHHHHHHHHEECCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHE
TLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKIKVTPHAGTILLMENAKLLAVY
EEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCEEEEEE
LPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDYPELPEVA
CCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCCCCHHH
ETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGPDATDAKNNA
HCCCCHHHCCEEHHHHHHHHHCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHH
KLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKGENGFGYDPVFI
HHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCCEEE
VGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS
EECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AETKNKCGACHLMSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAA
CCCCCCCCEEEHHHHHHHHEECCCCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHE
TLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKIKVTPHAGTILLMENAKLLAVY
EEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCEEEEEE
LPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDYPELPEVA
CCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCCCCHHH
ETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGPDATDAKNNA
HCCCCHHHCCEEHHHHHHHHHCCEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHH
KLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKGENGFGYDPVFI
HHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCCEEE
VGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS
EECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]