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The map label for this gene is oppA [H]

Identifier: 94993642

GI number: 94993642

Start: 257834

End: 259822

Strand: Direct

Name: oppA [H]

Synonym: MGAS10750_Spy0246

Alternate gene names: 94993642

Gene position: 257834-259822 (Clockwise)

Preceding gene: 94993639

Following gene: 94993643

Centisome position: 13.31

GC content: 40.02

Gene sequence:

>1989_bases
GTGACTTTTATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGG
TAATAAAAATGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATT
ATATTTTGACTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGT
AATTTAGTACCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGT
CTCTTGGTATACGGCTGATGGTGAAGAATATGCCCCAGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTG
ACGATAAATCAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTT
AAAGAAGTTGGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAA
AACAACTTATAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCAT
CATCAATCCTTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAAC
TACTGGGATGCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAA
GAACTTTGACAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATG
CTGATAACATTACTTACGGAATGTTGACTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAAC
ACTAAGAAAGACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAATTTGC
TTTTGACCGAGCGTCATTCCAAGCACAAACTGCAGGTCAAGATGCCAAAACAAAAGCCTTACGTAACATGCTTGTGCCAC
CAACTTTTGTAACCGTTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGTGATGAATGGAAA
GACGTTAACTTAGCTGATGCTCAAGATGGTTTCTATAATCCAGAAAAAGCAAAAGTTGAATTTGCAAAAGCCAAAGAAGC
TTTGACAGCTGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAGGCAAACGCAGCAACTGTTCAGGAAG
CCCAGTCTTTCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAAAATGTCATTGTCAATGTTCTTGAAACAGAAACATCA
ACTCACGAAGCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATCATTTCATCATGGTGGGGACCAGA
CTACCAAGATCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGTGGATCTGTTATCCAAAAACTTGGAATCAAAG
CAGGTCAAAATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACTTACCAAACTCTTCTTGATGAAGCAGCAGCAATTACA
GACGACAACGATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAGTGCCGTAGATATTCCAGTTGT
GGCATTGGGTGGCACTCCTCGAGTTACTAAAGCCGTTCCATTTAGCGGTGCCTTTGCCTGGGCAGGTGCTAAAGGTCCTG
CTTCTGTATATTATTATAAAGGAATGAAACTTCAAGACAAACCTGTCACAGCAAAACAATTCGAAAAAGCAAAAGAAAAA
TGGATGAAAGCAAAGGCTAAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Upstream 100 bases:

>100_bases
TTCATTTCATTATTTTCTTTAAGAAAGTTTTATGATATAATGTCTTCAATTAACCAATTTCATTTAGCAATTGCCAAAAA
ATGAAAAATAAAGTTTAGGG

Downstream 100 bases:

>100_bases
AACGATGTTCAAAAGAACTTTCTCGTTTATGTGAGAGAGTTCTTTTGAACTATTGAGGATAACTATGAAAAAATACATTT
TAAACCGTATCATGCGATCG

Product: Oligopeptide-binding protein oppA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MTFMKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYG
NLVPSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDF
KEVGVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNEN
YWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKN
TKKDPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWK
DVNLADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETS
THEAQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAIT
DDNDARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEK
WMKAKAKSNAKYAEKLADHVEK

Sequences:

>Translated_662_residues
MTFMKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYG
NLVPSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDF
KEVGVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNEN
YWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKN
TKKDPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWK
DVNLADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETS
THEAQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAIT
DDNDARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEK
WMKAKAKSNAKYAEKLADHVEK
>Mature_661_residues
TFMKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGN
LVPSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFK
EVGVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENY
WDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNT
KKDPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWKD
VNLADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETST
HEAQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITD
DNDARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEKW
MKAKAKSNAKYAEKLADHVEK

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=396, Percent_Identity=26.5151515151515, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081878, Length=283, Percent_Identity=28.2685512367491, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1787495, Length=522, Percent_Identity=23.9463601532567, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789966, Length=579, Percent_Identity=23.8341968911917, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 72807; Mature: 72675

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFMKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCC
GTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPV
CHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCEEEECCCCCCCCC
TAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEVGVKALDDKTVQYTLNKP
CHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHCCEEECCCEEEEEECCC
ESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNEN
HHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
YWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYG
CCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEE
MLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQ
EEECCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCC
DAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWKDVNLADAQDGFYNPEKAKVE
HHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
FAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETS
HHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
THEAQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDV
CHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCE
VAAAGLDTYQTLLDEAAAITDDNDARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVP
EEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCCCCEEEEECCCCCCEEECC
FSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEKWMKAKAKSNAKYAEKLADHV
CCCCEEECCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EK
CC
>Mature Secondary Structure 
TFMKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCC
GTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPV
CHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCEEEECCCCCCCCC
TAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEVGVKALDDKTVQYTLNKP
CHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHCCEEECCCEEEEEECCC
ESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNEN
HHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCC
YWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYG
CCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEE
MLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQ
EEECCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCC
DAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWKDVNLADAQDGFYNPEKAKVE
HHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
FAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETS
HHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
THEAQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDV
CHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCE
VAAAGLDTYQTLLDEAAAITDDNDARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVP
EEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEECCCCCCEEEEECCCCCCEEECC
FSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEKWMKAKAKSNAKYAEKLADHV
CCCCEEECCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8051706; 11463916 [H]