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The map label for this gene is sufD [H]

Identifier: 94993636

GI number: 94993636

Start: 250383

End: 251645

Strand: Direct

Name: sufD [H]

Synonym: MGAS10750_Spy0240

Alternate gene names: 94993636

Gene position: 250383-251645 (Clockwise)

Preceding gene: 94993635

Following gene: 94993637

Centisome position: 12.93

GC content: 42.52

Gene sequence:

>1263_bases
ATGACAAAAGAAAAACTAGTGGCTTTTTCGCAAGCCCACGCTGAGCCTGCTTGGCTGCAAGAACGGCGTTTAGCGGCATT
AGAAGCCATTCCAAATTTGGAATTACCAACCATCGAAAGGGTTAAATTTCACCGTTGGAATCTAGGAGATGGTACCTTAA
CAGAAAATGAAAGTCTAGCTAGTGTTCCAGATTTTATAGCTATTGGAGATAACCCAAAGCTTGTTCAGGTAGGCACGCAA
ACAGTCTTAGAACAGTTACCAATGGCGTTAATTGACAAGGGAGTTGTTTTCAGTGATTTTTATACGGCGCTTGAGGAAAT
CCCAGAAGTAATTGAAGCTCATTTTGGTCAGGCATTAGCTTTTGATGAAGACAAACTAGCTGCCTACCACACTGCTTATT
TTAATAGCGCAGCCGTGCTCTACGTTCCTGATCACTTGGAAATCACAACTCCTATTGAAGCTATTTTCTTACAAGATAGT
GACAGTGACGTTCCTTTTAACAAGCATGTTCTAGTGATTGCAGGAAAAGAAAGTAAGTTCACCTATTTAGAGCGTTTTGA
ATCTATTGGCAATGCCACTCAAAAGACCAGCGCTAATATCAGTGTAGAAGTGATTGCTCAAGCAGGCAGCCAGATTAAAT
TCTCGGCTATCGACCGCTTAGGTCCTTCAGTGACAACCTATATTAGCCGTCGAGGACGTTTAGAGAAGGATGCCAACATT
GATTGGACCTTAGCTGTGATGAATGAAGGCAATGTCATTGCTGATTTTGACAGTGATTTGATTGGTCAGGGCTCACAAGC
TGATTTGAAAGTTGTTGCAGCCTCAAGTGGTCGTCAGGTACAAGGTATTGACACGCGCGTGACCAACTATGGTCAACGTA
CGGTCGGTCATATTTTACAGCATGGTGTGATTTTGGAACGTGGCACCTTAACGTTTAACGGGATTGGTCATATTCTAAAA
GGCGCTAAGGGAGCTGATGCTCAACAAGAAAGCCGTGTTTTGATGCTTTCTGACCAAGCAAGAGCCGATGCCAATCCAAT
CCTCTTAATTGATGAAAATGAAGTAACAGCAGGTCATGCAGCTTCTATCGGTCAGGTTGACCCTGAAGATATGTATTACT
TGATGAGTCGAGGACTGGATCAAGAAACAGCAGAACGATTGGTTATTAGAGGATTCCTAGGAGCGGTTATCGCTGAAATT
CCTATTCCATCAGTCCGCCAAGAGATTATTAAGGTTTTAGATGAGAAATTGCTTAATCGTTAA

Upstream 100 bases:

>100_bases
AGTTAAGTTTTTGGAGACAATTACTTTAGCTTTCTACAAAAAGCTAGGTGATGTTCTATATACCCAGCCAATTTAAAAAC
CAGAGACAAAGGATTGACAG

Downstream 100 bases:

>100_bases
GACCTACTGCCAAAAAGAAAGAGGTTAGTATTGCTAGACGCAAAAGACATCAAACAAGACTTTCAAATCTTAAATCAACA
AGTCAATGATGAACCCCTTG

Product: SufD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFHRWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQ
TVLEQLPMALIDKGVVFSDFYTALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAIDRLGPSVTTYISRRGRLEKDANI
DWTLAVMNEGNVIADFDSDLIGQGSQADLKVVAASSGRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILK
GAKGADAQQESRVLMLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGFLGAVIAEI
PIPSVRQEIIKVLDEKLLNR

Sequences:

>Translated_420_residues
MTKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFHRWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQ
TVLEQLPMALIDKGVVFSDFYTALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAIDRLGPSVTTYISRRGRLEKDANI
DWTLAVMNEGNVIADFDSDLIGQGSQADLKVVAASSGRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILK
GAKGADAQQESRVLMLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGFLGAVIAEI
PIPSVRQEIIKVLDEKLLNR
>Mature_419_residues
TKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFHRWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQT
VLEQLPMALIDKGVVFSDFYTALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDSD
SDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAIDRLGPSVTTYISRRGRLEKDANID
WTLAVMNEGNVIADFDSDLIGQGSQADLKVVAASSGRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKG
AKGADAQQESRVLMLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGFLGAVIAEIP
IPSVRQEIIKVLDEKLLNR

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=441, Percent_Identity=20.1814058956916, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1787971, Length=254, Percent_Identity=22.4409448818898, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000825
- InterPro:   IPR011542 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 46059; Mature: 45928

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFHRWNLGDGTLTENESLA
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEECCCCCCCCCCCCC
SVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYTALEEIPEVIEAHFGQALA
CCCCEEEECCCCCEEEECHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEE
FDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDSDSDVPFNKHVLVIAGKESKF
CCCCHHHHHHHHHHCCEEEEEECCCCEEECCEEEEEEECCCCCCCCCCEEEEEECCCCCH
TYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAIDRLGPSVTTYISRRGRLEKDANI
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEHHHHHCCCHHHHHHHHCCCCCCCCCC
DWTLAVMNEGNVIADFDSDLIGQGSQADLKVVAASSGRQVQGIDTRVTNYGQRTVGHILQ
CEEEEEECCCCEEEECCCHHCCCCCCCCEEEEEECCCCEEECCHHHHHHCCHHHHHHHHH
HGVILERGTLTFNGIGHILKGAKGADAQQESRVLMLSDQARADANPILLIDENEVTAGHA
CCEEEECCCEEECCHHHHHCCCCCCCCHHCCCEEEEECCCCCCCCCEEEEECCCCCCCCC
ASIGQVDPEDMYYLMSRGLDQETAERLVIRGFLGAVIAEIPIPSVRQEIIKVLDEKLLNR
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKEKLVAFSQAHAEPAWLQERRLAALEAIPNLELPTIERVKFHRWNLGDGTLTENESLA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEECCCCCCCCCCCCC
SVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYTALEEIPEVIEAHFGQALA
CCCCEEEECCCCCEEEECHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEE
FDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDSDSDVPFNKHVLVIAGKESKF
CCCCHHHHHHHHHHCCEEEEEECCCCEEECCEEEEEEECCCCCCCCCCEEEEEECCCCCH
TYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAIDRLGPSVTTYISRRGRLEKDANI
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEHHHHHCCCHHHHHHHHCCCCCCCCCC
DWTLAVMNEGNVIADFDSDLIGQGSQADLKVVAASSGRQVQGIDTRVTNYGQRTVGHILQ
CEEEEEECCCCEEEECCCHHCCCCCCCCEEEEEECCCCEEECCHHHHHHCCHHHHHHHHH
HGVILERGTLTFNGIGHILKGAKGADAQQESRVLMLSDQARADANPILLIDENEVTAGHA
CCEEEECCCEEECCHHHHHCCCCCCCCHHCCCEEEEECCCCCCCCCEEEEECCCCCCCCC
ASIGQVDPEDMYYLMSRGLDQETAERLVIRGFLGAVIAEIPIPSVRQEIIKVLDEKLLNR
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]