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The map label for this gene is yggW [C]

Identifier: 94986421

GI number: 94986421

Start: 2443249

End: 2444460

Strand: Reverse

Name: yggW [C]

Synonym: Dgeo_2324

Alternate gene names: 94986421

Gene position: 2444460-2443249 (Counterclockwise)

Preceding gene: 94986422

Following gene: 94986420

Centisome position: 99.08

GC content: 67.82

Gene sequence:

>1212_bases
GTGAGGGCGGGCGGGGCAACAAACGCAACCTTCACCCCGCACGGCCTCCCGCTTCCCGCGTACCCTGCCCCCGTGCCTGC
CCTCGACTCCACCGTCCGCCACCTGTATGTCCACGTGCCGTTTTGCCCGACCATCTGTCCGTACTGTGATTTTCATGTGC
TGACACGCCGGGCCGGGCTGGTCGAAAAGTATCTGGAGCGGGTGGAGGAGGAGGCCGCGCAGCTCGCGGCGGAGTACACC
GTGGATCTCGACACGGTGTATATCGGCGGCGGCACTCCCAGCTTTCTGCGCGATGCAGAAATCACCGCGCTTGCGCAGAG
CATCCGCCGTCATCTGGGCTGGGGCCGCCTGGAAAACACGCTGGAGATCAACCCGGGGACCGTCAGCGCGGGGCGGGCGG
CCCTGTGGCGCGAACTGGGTTTTGACCGCGCTTCCGTCGGCGTGCAGAGCCTCGACGACGCCACCCTGAGGTTCCTGGGC
CGCCAGCATGACGCGCGGCAGGCCCAGGAGGCCGTAACCACGCTGGTGGAGACGGGCTTGCGTGTGAGTGGTGACCTGAT
CACCGCCGTGCCCGGTCAGCCGCTCGCGGAGGACATTCGCGGGCTGGTGGACCTGGGAGTGGGCCATGTGAGCGCCTACA
CCCTCACCATCGAGCCGGGCACCGAGTTTGCCCGCCGCGGCGTGACCGTGGAGGAGGACGACGAACGCGCGGGCTTTACA
CAAACGGAGGAACTCCTCACCGCGCTGGGTTTCACCCGCTACGAGGTGAGCAACTACGCGCGCCCCGGCCAGGAGTCCCG
CCACAACCTGGCCTACTGGCACAACCGGACATACCTGGGCCTGGGACCGGGGGCAGCGGGCCACTATCCCGTCGCGCAGT
GCCAGCAGTCGCTCCCCTCTTCCCCCCTCACCCTGCGCCGCACCAACCCCCACCTCCACGCGTGGCTGACGGGCGAGCAG
GGAGAAATGCAGCTGGTTGATGCCGAGGAGTACGTGACCGACGCCCTCTTTATGGGCCTGAGACTGCGGGAGGGCGTGAA
CCTCGCGGATCTGACGCGGCGCAGTGGCCTGAACATACGCGAACGGTACGCTTCGGCCATTGCCGCGAATGTGCGCCGGG
GTCTGCTCGTGCTGGAAGGTGAACGGCTGCGCGCCACGCCGCCCGGCTGGTGGACCCTCAACCAAGTGGTGGCCGACTTT
CTGGAGGCGTGA

Upstream 100 bases:

>100_bases
CGAGTGCCGTAGCATCCCTGAACGTGCCGGTCATCGTCACGTCGCCGGATCAGGTGCGAGCCGTGCTGGAAGCCTGGATG
GACGCGACGCCACACGGGCG

Downstream 100 bases:

>100_bases
ACAACTCACCAGCACGAGTGGTCAATGCACCTGATCCAACTCCCGAAAAGCGTGATTGGTGCGGCCTGAGGGGGCGCGTT
AGACTGCCCGCATGACGAAA

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MRAGGATNATFTPHGLPLPAYPAPVPALDSTVRHLYVHVPFCPTICPYCDFHVLTRRAGLVEKYLERVEEEAAQLAAEYT
VDLDTVYIGGGTPSFLRDAEITALAQSIRRHLGWGRLENTLEINPGTVSAGRAALWRELGFDRASVGVQSLDDATLRFLG
RQHDARQAQEAVTTLVETGLRVSGDLITAVPGQPLAEDIRGLVDLGVGHVSAYTLTIEPGTEFARRGVTVEEDDERAGFT
QTEELLTALGFTRYEVSNYARPGQESRHNLAYWHNRTYLGLGPGAAGHYPVAQCQQSLPSSPLTLRRTNPHLHAWLTGEQ
GEMQLVDAEEYVTDALFMGLRLREGVNLADLTRRSGLNIRERYASAIAANVRRGLLVLEGERLRATPPGWWTLNQVVADF
LEA

Sequences:

>Translated_403_residues
MRAGGATNATFTPHGLPLPAYPAPVPALDSTVRHLYVHVPFCPTICPYCDFHVLTRRAGLVEKYLERVEEEAAQLAAEYT
VDLDTVYIGGGTPSFLRDAEITALAQSIRRHLGWGRLENTLEINPGTVSAGRAALWRELGFDRASVGVQSLDDATLRFLG
RQHDARQAQEAVTTLVETGLRVSGDLITAVPGQPLAEDIRGLVDLGVGHVSAYTLTIEPGTEFARRGVTVEEDDERAGFT
QTEELLTALGFTRYEVSNYARPGQESRHNLAYWHNRTYLGLGPGAAGHYPVAQCQQSLPSSPLTLRRTNPHLHAWLTGEQ
GEMQLVDAEEYVTDALFMGLRLREGVNLADLTRRSGLNIRERYASAIAANVRRGLLVLEGERLRATPPGWWTLNQVVADF
LEA
>Mature_403_residues
MRAGGATNATFTPHGLPLPAYPAPVPALDSTVRHLYVHVPFCPTICPYCDFHVLTRRAGLVEKYLERVEEEAAQLAAEYT
VDLDTVYIGGGTPSFLRDAEITALAQSIRRHLGWGRLENTLEINPGTVSAGRAALWRELGFDRASVGVQSLDDATLRFLG
RQHDARQAQEAVTTLVETGLRVSGDLITAVPGQPLAEDIRGLVDLGVGHVSAYTLTIEPGTEFARRGVTVEEDDERAGFT
QTEELLTALGFTRYEVSNYARPGQESRHNLAYWHNRTYLGLGPGAAGHYPVAQCQQSLPSSPLTLRRTNPHLHAWLTGEQ
GEMQLVDAEEYVTDALFMGLRLREGVNLADLTRRSGLNIRERYASAIAANVRRGLLVLEGERLRATPPGWWTLNQVVADF
LEA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=293, Percent_Identity=36.1774744027304, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1789325, Length=382, Percent_Identity=33.2460732984293, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87082341, Length=242, Percent_Identity=25.2066115702479, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44274; Mature: 44274

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGGATNATFTPHGLPLPAYPAPVPALDSTVRHLYVHVPFCPTICPYCDFHVLTRRAGL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHH
VEKYLERVEEEAAQLAAEYTVDLDTVYIGGGTPSFLRDAEITALAQSIRRHLGWGRLENT
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LEINPGTVSAGRAALWRELGFDRASVGVQSLDDATLRFLGRQHDARQAQEAVTTLVETGL
EEECCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
RVSGDLITAVPGQPLAEDIRGLVDLGVGHVSAYTLTIEPGTEFARRGVTVEEDDERAGFT
EECCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHCCCCCCCCCCCCCCC
QTEELLTALGFTRYEVSNYARPGQESRHNLAYWHNRTYLGLGPGAAGHYPVAQCQQSLPS
HHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHCCC
SPLTLRRTNPHLHAWLTGEQGEMQLVDAEEYVTDALFMGLRLREGVNLADLTRRSGLNIR
CCEEEEECCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
ERYASAIAANVRRGLLVLEGERLRATPPGWWTLNQVVADFLEA
HHHHHHHHHHHHCCEEEEECCCEECCCCCCEEHHHHHHHHHCC
>Mature Secondary Structure
MRAGGATNATFTPHGLPLPAYPAPVPALDSTVRHLYVHVPFCPTICPYCDFHVLTRRAGL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHH
VEKYLERVEEEAAQLAAEYTVDLDTVYIGGGTPSFLRDAEITALAQSIRRHLGWGRLENT
HHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCE
LEINPGTVSAGRAALWRELGFDRASVGVQSLDDATLRFLGRQHDARQAQEAVTTLVETGL
EEECCCCCCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
RVSGDLITAVPGQPLAEDIRGLVDLGVGHVSAYTLTIEPGTEFARRGVTVEEDDERAGFT
EECCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHCCCCCCCCCCCCCCC
QTEELLTALGFTRYEVSNYARPGQESRHNLAYWHNRTYLGLGPGAAGHYPVAQCQQSLPS
HHHHHHHHHCCHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHCCC
SPLTLRRTNPHLHAWLTGEQGEMQLVDAEEYVTDALFMGLRLREGVNLADLTRRSGLNIR
CCEEEEECCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHH
ERYASAIAANVRRGLLVLEGERLRATPPGWWTLNQVVADFLEA
HHHHHHHHHHHHCCEEEEECCCEECCCCCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]