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The map label for this gene is ubiA [H]

Identifier: 94986419

GI number: 94986419

Start: 2440592

End: 2441551

Strand: Reverse

Name: ubiA [H]

Synonym: Dgeo_2322

Alternate gene names: 94986419

Gene position: 2441551-2440592 (Counterclockwise)

Preceding gene: 94986420

Following gene: 94986418

Centisome position: 98.96

GC content: 66.35

Gene sequence:

>960_bases
GTGGCCGCTCTTCTGTGGCCCGGTCCGTGCTCCTTTCACAGCATGAGTTGCTGGGCAGGCGTATGCTGCGGCACTGTGAG
TGCGGCGGTGCGGGTGAAGACGTATCTGGATCTGGTGAAGTTCGAACATACGGTGTTCGCCCTGCCCTTCGCCTACGCGG
GAATGCTGTTGGCGAGCTTGCAGACCCGCGGCACCGGTTGGCCGGGCTGGCACACCCTGATCTGGGTGACGGTGGCGATG
GCCGCGGCGCGCACGGCGGCGATGGGCGCCAACCGGGTGATCGACCGCTTCATCGACGCCCGCAATCCCCGCACGGCGGG
CCGCGAGGTGCCCAGCGGCAAGGTCAGCCCCGGGCAGGCCTGGACGCTGGTGGTGGTCAGCCTGCTGGTGCTTGCGTTTG
CCGCCGCGCAGCTGAACCCCCTCTGTTTGGCGCTGCTGCCGCTGGCAGTGGTGTTCCTGATCGGCTACCCCTACACCAAG
CGCTTCACCTGGCTGTGTCATGCCTGGCTGGGCGTGACCGATGGCGCGGCAGCGGCGGGCGGCTGGATTGCTGTCACCGG
CCATTTTGCCCCAGCAGCCTGGCTGCTCTGGGCGGTCGTCATCTTTTGGATGATCGGCCTCGACGTGATCTATGCCACGC
TGGACTACCGCTTTGACCTCGCCCATGGCATCCGCAGCATTCCCGCGCGCTTCGGCATCCAGCGTGCCCTGCGGATAGCC
GCTGCCAGTCATGCCCTTACCTTCGTCCTGCTGCTGCTGGTGGGAGTAGCGACCGGCGCGAGTTTCTGGTACTACCTCGC
CGCACTGGTGATGGGAGCCATCTTGCTCTACGAGCACCGCATCGTCAATCCGGACGACCTGGCCCGCGTGAACGTGGCCT
TTTTCGACGCGAACATGTGGCTGGCCCTCACCATGCTGGCGGGCGTGCTGGTGGACGTGACGTGGCGGACCCTGACCTGA

Upstream 100 bases:

>100_bases
GCTCAGCTGGATAGAGCGGCCCCCTCCTAAGGGGCAGGTCCCGCGTTCGAATCGCGGCGAGTGCACCAAAAACCCCCCGC
CTGGCGGGGTTTTTTGTTGT

Downstream 100 bases:

>100_bases
GGGCGCTTATTCCGCTTTCGGCGGCGCGGGCCTTTGTGGAAGGTGATGAACGGTTGGCCCTCACGCTGCTGCGGCGGGCG
CGGGACGGTGAGGTGCCCGG

Product: 4-hydroxybenzoate polyprenyltransferase, putative

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAALLWPGPCSFHSMSCWAGVCCGTVSAAVRVKTYLDLVKFEHTVFALPFAYAGMLLASLQTRGTGWPGWHTLIWVTVAM
AAARTAAMGANRVIDRFIDARNPRTAGREVPSGKVSPGQAWTLVVVSLLVLAFAAAQLNPLCLALLPLAVVFLIGYPYTK
RFTWLCHAWLGVTDGAAAAGGWIAVTGHFAPAAWLLWAVVIFWMIGLDVIYATLDYRFDLAHGIRSIPARFGIQRALRIA
AASHALTFVLLLLVGVATGASFWYYLAALVMGAILLYEHRIVNPDDLARVNVAFFDANMWLALTMLAGVLVDVTWRTLT

Sequences:

>Translated_319_residues
MAALLWPGPCSFHSMSCWAGVCCGTVSAAVRVKTYLDLVKFEHTVFALPFAYAGMLLASLQTRGTGWPGWHTLIWVTVAM
AAARTAAMGANRVIDRFIDARNPRTAGREVPSGKVSPGQAWTLVVVSLLVLAFAAAQLNPLCLALLPLAVVFLIGYPYTK
RFTWLCHAWLGVTDGAAAAGGWIAVTGHFAPAAWLLWAVVIFWMIGLDVIYATLDYRFDLAHGIRSIPARFGIQRALRIA
AASHALTFVLLLLVGVATGASFWYYLAALVMGAILLYEHRIVNPDDLARVNVAFFDANMWLALTMLAGVLVDVTWRTLT
>Mature_318_residues
AALLWPGPCSFHSMSCWAGVCCGTVSAAVRVKTYLDLVKFEHTVFALPFAYAGMLLASLQTRGTGWPGWHTLIWVTVAMA
AARTAAMGANRVIDRFIDARNPRTAGREVPSGKVSPGQAWTLVVVSLLVLAFAAAQLNPLCLALLPLAVVFLIGYPYTKR
FTWLCHAWLGVTDGAAAAGGWIAVTGHFAPAAWLLWAVVIFWMIGLDVIYATLDYRFDLAHGIRSIPARFGIQRALRIAA
ASHALTFVLLLLVGVATGASFWYYLAALVMGAILLYEHRIVNPDDLARVNVAFFDANMWLALTMLAGVLVDVTWRTLT

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=297, Percent_Identity=27.6094276094276, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790473, Length=215, Percent_Identity=29.3023255813954, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553718, Length=228, Percent_Identity=26.7543859649123, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324370, Length=180, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355567, Length=232, Percent_Identity=30.6034482758621, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34652; Mature: 34521

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AALLWPGPCSFHSMSCWAGVCCGTVSAAVRVKTYLDLVKFEHTVFALPFAYAGMLLASL
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTRGTGWPGWHTLIWVTVAMAAARTAAMGANRVIDRFIDARNPRTAGREVPSGKVSPGQA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
WTLVVVSLLVLAFAAAQLNPLCLALLPLAVVFLIGYPYTKRFTWLCHAWLGVTDGAAAAG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCC
GWIAVTGHFAPAAWLLWAVVIFWMIGLDVIYATLDYRFDLAHGIRSIPARFGIQRALRIA
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASHALTFVLLLLVGVATGASFWYYLAALVMGAILLYEHRIVNPDDLARVNVAFFDANMW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEEEECCHHH
LALTMLAGVLVDVTWRTLT
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA