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The map label for this gene is accD [H]

Identifier: 94986276

GI number: 94986276

Start: 2294952

End: 2295806

Strand: Reverse

Name: accD [H]

Synonym: Dgeo_2177

Alternate gene names: 94986276

Gene position: 2295806-2294952 (Counterclockwise)

Preceding gene: 94986277

Following gene: 94986275

Centisome position: 93.05

GC content: 66.43

Gene sequence:

>855_bases
ATGGCGCTCGACCGTTTTTTCCGCAGACGCCGCCCGCAACCGCAGGGCACAGGTGAACTGCCGGACCTCTGGACCCAGTG
CCCCCAGTGCAAGCAGGGGCTGTACAACCGTGACCTCGCCGCGCACAGCTTTGTTTGTCCCAAGTGCGGGCACCATTTTC
GTCTCGATGCGGGGCAACGCCTGAATCTGCTGCTGGACGAGGGCAGCTTCAAGCAGCAGTCGGGTCGCATCCACCCCACG
GATCCGCTGAATTTTCAGGACACTGAACCCTACCCCGAGCGGCTCGCCCGCGCGCAGCAGAAGACAGGCCGCCCCGACGC
CATCCTCACCGGCACCGGCACCATCGAGGGGCTTGCGGTAACGGTGGCCGCGATGGATTTTGCCTTTAGTGGCGGCAGCA
TGGGCAGCGTGGTCGGGGAGGAGATCGCCCGCGCCGCCGAGAGTGCTGCTGAGGCAGGGACCCCCTTGGTGCTGGTGGCC
GCCAGCGGCGGGGCCAGGATGCAGGAGAGTGCCCTCTCGCTGATGCAGATGGCAAAGACCACGGTGGCGCTGGAAGCCCT
CTCCCAGCGCGGCCTGCCCTATATCAGCATTCTGAGCGATCCGACAACCGGAGGTGTGACTGCCTCCTTCGCCACCATTG
CGGACGTGATCATCGCGGAACCCGGAGCGCTGATTGGCTTTGCTGGGCCGCGCGTCATCCAGCAGACCATTCGCCAGAAT
CTGCCGGAGGGCTTCCAGCGGGCCGAGTTCCTGCTGGAGCACGGCATGGTGGACGACGTGGTGGACCGCCGCGAGCAGCG
CGCGTACCTCGCCCGCCTGCTGGGTGTCCTGACCAAGCGGGAGGTGAGCGCGTGA

Upstream 100 bases:

>100_bases
TTGCACCCGGTTCAGTTGTGCGGCTGCTGTGTGTGTTGGCCTGTGCGGCCTCTACAATGGCGCGGGAAGCCGTTTTGTTC
CCCCCGAAGGAGTGAAGCGT

Downstream 100 bases:

>100_bases
GCAGCGATACGCTGAGCAGACTGGAAGCCCAAGTGCGCGACCTGGAGGCCACGGCTCGCGAAACCGGGCAGAATCTCGAC
GCGGCCCTGATGCCCCTGCG

Product: acetyl-CoA carboxylase, carboxyl transferase, beta subunit

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MALDRFFRRRRPQPQGTGELPDLWTQCPQCKQGLYNRDLAAHSFVCPKCGHHFRLDAGQRLNLLLDEGSFKQQSGRIHPT
DPLNFQDTEPYPERLARAQQKTGRPDAILTGTGTIEGLAVTVAAMDFAFSGGSMGSVVGEEIARAAESAAEAGTPLVLVA
ASGGARMQESALSLMQMAKTTVALEALSQRGLPYISILSDPTTGGVTASFATIADVIIAEPGALIGFAGPRVIQQTIRQN
LPEGFQRAEFLLEHGMVDDVVDRREQRAYLARLLGVLTKREVSA

Sequences:

>Translated_284_residues
MALDRFFRRRRPQPQGTGELPDLWTQCPQCKQGLYNRDLAAHSFVCPKCGHHFRLDAGQRLNLLLDEGSFKQQSGRIHPT
DPLNFQDTEPYPERLARAQQKTGRPDAILTGTGTIEGLAVTVAAMDFAFSGGSMGSVVGEEIARAAESAAEAGTPLVLVA
ASGGARMQESALSLMQMAKTTVALEALSQRGLPYISILSDPTTGGVTASFATIADVIIAEPGALIGFAGPRVIQQTIRQN
LPEGFQRAEFLLEHGMVDDVVDRREQRAYLARLLGVLTKREVSA
>Mature_283_residues
ALDRFFRRRRPQPQGTGELPDLWTQCPQCKQGLYNRDLAAHSFVCPKCGHHFRLDAGQRLNLLLDEGSFKQQSGRIHPTD
PLNFQDTEPYPERLARAQQKTGRPDAILTGTGTIEGLAVTVAAMDFAFSGGSMGSVVGEEIARAAESAAEAGTPLVLVAA
SGGARMQESALSLMQMAKTTVALEALSQRGLPYISILSDPTTGGVTASFATIADVIIAEPGALIGFAGPRVIQQTIRQNL
PEGFQRAEFLLEHGMVDDVVDRREQRAYLARLLGVLTKREVSA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=192, Percent_Identity=28.125, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1788655, Length=265, Percent_Identity=53.9622641509434, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI25147359, Length=229, Percent_Identity=27.9475982532751, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147362, Length=229, Percent_Identity=27.9475982532751, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 30674; Mature: 30543

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDRFFRRRRPQPQGTGELPDLWTQCPQCKQGLYNRDLAAHSFVCPKCGHHFRLDAGQR
CCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCEEECCCCCC
LNLLLDEGSFKQQSGRIHPTDPLNFQDTEPYPERLARAQQKTGRPDAILTGTGTIEGLAV
EEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
TVAAMDFAFSGGSMGSVVGEEIARAAESAAEAGTPLVLVAASGGARMQESALSLMQMAKT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
TVALEALSQRGLPYISILSDPTTGGVTASFATIADVIIAEPGALIGFAGPRVIQQTIRQN
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHH
LPEGFQRAEFLLEHGMVDDVVDRREQRAYLARLLGVLTKREVSA
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALDRFFRRRRPQPQGTGELPDLWTQCPQCKQGLYNRDLAAHSFVCPKCGHHFRLDAGQR
CHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCEEECCCCCC
LNLLLDEGSFKQQSGRIHPTDPLNFQDTEPYPERLARAQQKTGRPDAILTGTGTIEGLAV
EEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
TVAAMDFAFSGGSMGSVVGEEIARAAESAAEAGTPLVLVAASGGARMQESALSLMQMAKT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
TVALEALSQRGLPYISILSDPTTGGVTASFATIADVIIAEPGALIGFAGPRVIQQTIRQN
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHH
LPEGFQRAEFLLEHGMVDDVVDRREQRAYLARLLGVLTKREVSA
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA