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The map label for this gene is hemA [H]

Identifier: 94986227

GI number: 94986227

Start: 2240116

End: 2241213

Strand: Reverse

Name: hemA [H]

Synonym: Dgeo_2128

Alternate gene names: 94986227

Gene position: 2241213-2240116 (Counterclockwise)

Preceding gene: 94986228

Following gene: 94986226

Centisome position: 90.84

GC content: 69.76

Gene sequence:

>1098_bases
GTGACCCTGACGTGCCCGACCGCCCGCGCCTTCCTGGCCCAGCCGCAGGTGCCGCCCCTCGCTCCGCTGGATTTTGCCGT
GATTGGCCTGAACCACCAGACCGCCCCGGTTGAGGTGCGGGAACAGGCCGCAGTGCGTGCTGGAGACGAAGGGAAAGTGC
TCCAGCACCTCTCCCGCTATGCCCGCGAGGTGATGCTGCTCAACACCTGCAACCGCACCGAGGTCTACCTGGCGGGGCTG
CAGGGCGACCCGCTGCGCGCCTTTGAGAGTGGTTGGGGCCGGGCGCTGGACGGCCACCTGTATGTTCACCGGGGTGAGGC
TGCCGCCACGCATCTCTACCGCGTCGCGGCGGGGCTGGACAGCCTGGTGATCGGGGAGACCCAGATCCAGGGGCAGGTGA
AGCGGGCCTGGCAGGAGGCGCACGCCCGCGGCCTTTCTGGCACCCTGCTGAACAAGGTGGCGCAGGGGGCCTTGGCTGCC
GGGAAGCGTGTCCGCAGTGAAACCGGCCTCAGTGACAAGGTGGTCAGCGTATCGAGCGCCGCCGTTGAACTCGCCGAGGC
CGCCCTGGGTGAGCTCAGGCACCGCACGGCCCTGATTCTGGGCGCGGGTGAGACGGCCGAACTCACCCTCACGCACCTGC
GGGCAGCGGGCGTGCAGGACGTGATCGTGGTCAACCGCACCGAGGCGCGGGCTCGGCAGCTTGCAGATAAGCTGGGGGGC
CGAGCCTGCGCGGCCGAGTACCTCCACGAGGTTTTGCCCGAGGCGGACGTGGTGATTGCCTCCAGCGCGGCCCCCCACTA
TGTCCTGCATGGCGAGGGCGTGCGCGCGGCGCTGGCAAAGCGCCCGGAGCGCCCCATCTTCCTGATCGACATCAGCGTGC
CGCGCATTCTCGATCCCGATATCCGTGCGGTGTCCGGTGCCCACCTCTACAACCTCGATGACCTCACCGCGATTGTCAGC
CGCAACCTGCAAAGCCGCCGCGCGGCCCTGCCGTACGCCGAGGCGATTATCCGCGAGGCGGTGGCCGACCTGCTGCGCTG
GCACCTGACCCGCGAGGCGCAGCTGGGACGGCGCGCGGTCGCGTTGGCCAGCGACTGA

Upstream 100 bases:

>100_bases
GGGCGCTCACCCTGGACCCTGCCGCACGCGAAGACGCACTGGCGGGCTTGCGTGCCGAGATCCGTACGGCGCTGGGTCTG
CCCGCTCTGGGGGGGGCCGC

Downstream 100 bases:

>100_bases
GGAGAGTTCCTGCGTACCGCGCACCACCAACGGCTCTCCCTTTTTCCCGTACCCTGCCCCTCATGTGGACCCGCATTCCT
TCCAGCGCCCTGCGGCTCAC

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTLTCPTARAFLAQPQVPPLAPLDFAVIGLNHQTAPVEVREQAAVRAGDEGKVLQHLSRYAREVMLLNTCNRTEVYLAGL
QGDPLRAFESGWGRALDGHLYVHRGEAAATHLYRVAAGLDSLVIGETQIQGQVKRAWQEAHARGLSGTLLNKVAQGALAA
GKRVRSETGLSDKVVSVSSAAVELAEAALGELRHRTALILGAGETAELTLTHLRAAGVQDVIVVNRTEARARQLADKLGG
RACAAEYLHEVLPEADVVIASSAAPHYVLHGEGVRAALAKRPERPIFLIDISVPRILDPDIRAVSGAHLYNLDDLTAIVS
RNLQSRRAALPYAEAIIREAVADLLRWHLTREAQLGRRAVALASD

Sequences:

>Translated_365_residues
MTLTCPTARAFLAQPQVPPLAPLDFAVIGLNHQTAPVEVREQAAVRAGDEGKVLQHLSRYAREVMLLNTCNRTEVYLAGL
QGDPLRAFESGWGRALDGHLYVHRGEAAATHLYRVAAGLDSLVIGETQIQGQVKRAWQEAHARGLSGTLLNKVAQGALAA
GKRVRSETGLSDKVVSVSSAAVELAEAALGELRHRTALILGAGETAELTLTHLRAAGVQDVIVVNRTEARARQLADKLGG
RACAAEYLHEVLPEADVVIASSAAPHYVLHGEGVRAALAKRPERPIFLIDISVPRILDPDIRAVSGAHLYNLDDLTAIVS
RNLQSRRAALPYAEAIIREAVADLLRWHLTREAQLGRRAVALASD
>Mature_364_residues
TLTCPTARAFLAQPQVPPLAPLDFAVIGLNHQTAPVEVREQAAVRAGDEGKVLQHLSRYAREVMLLNTCNRTEVYLAGLQ
GDPLRAFESGWGRALDGHLYVHRGEAAATHLYRVAAGLDSLVIGETQIQGQVKRAWQEAHARGLSGTLLNKVAQGALAAG
KRVRSETGLSDKVVSVSSAAVELAEAALGELRHRTALILGAGETAELTLTHLRAAGVQDVIVVNRTEARARQLADKLGGR
ACAAEYLHEVLPEADVVIASSAAPHYVLHGEGVRAALAKRPERPIFLIDISVPRILDPDIRAVSGAHLYNLDDLTAIVSR
NLQSRRAALPYAEAIIREAVADLLRWHLTREAQLGRRAVALASD

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=330, Percent_Identity=38.4848484848485, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 39230; Mature: 39099

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTCPTARAFLAQPQVPPLAPLDFAVIGLNHQTAPVEVREQAAVRAGDEGKVLQHLSRY
CEECCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
AREVMLLNTCNRTEVYLAGLQGDPLRAFESGWGRALDGHLYVHRGEAAATHLYRVAAGLD
HHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCCCEECCEEEEECCCHHHHHHHHHHHCCC
SLVIGETQIQGQVKRAWQEAHARGLSGTLLNKVAQGALAAGKRVRSETGLSDKVVSVSSA
CEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AVELAEAALGELRHRTALILGAGETAELTLTHLRAAGVQDVIVVNRTEARARQLADKLGG
HHHHHHHHHHHHHHHEEEEEECCCCCEEHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCC
RACAAEYLHEVLPEADVVIASSAAPHYVLHGEGVRAALAKRPERPIFLIDISVPRILDPD
HHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCC
IRAVSGAHLYNLDDLTAIVSRNLQSRRAALPYAEAIIREAVADLLRWHLTREAQLGRRAV
HHHCCCCEEECHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
ALASD
EECCC
>Mature Secondary Structure 
TLTCPTARAFLAQPQVPPLAPLDFAVIGLNHQTAPVEVREQAAVRAGDEGKVLQHLSRY
EECCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHH
AREVMLLNTCNRTEVYLAGLQGDPLRAFESGWGRALDGHLYVHRGEAAATHLYRVAAGLD
HHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCCCEECCEEEEECCCHHHHHHHHHHHCCC
SLVIGETQIQGQVKRAWQEAHARGLSGTLLNKVAQGALAAGKRVRSETGLSDKVVSVSSA
CEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AVELAEAALGELRHRTALILGAGETAELTLTHLRAAGVQDVIVVNRTEARARQLADKLGG
HHHHHHHHHHHHHHHEEEEEECCCCCEEHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCC
RACAAEYLHEVLPEADVVIASSAAPHYVLHGEGVRAALAKRPERPIFLIDISVPRILDPD
HHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCC
IRAVSGAHLYNLDDLTAIVSRNLQSRRAALPYAEAIIREAVADLLRWHLTREAQLGRRAV
HHHCCCCEEECHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
ALASD
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA