Click here to switch to the map view.

The map label for this gene is tolC [C]

Identifier: 94986218

GI number: 94986218

Start: 2230733

End: 2232169

Strand: Reverse

Name: tolC [C]

Synonym: Dgeo_2119

Alternate gene names: 94986218

Gene position: 2232169-2230733 (Counterclockwise)

Preceding gene: 94986219

Following gene: 94986217

Centisome position: 90.47

GC content: 71.19

Gene sequence:

>1437_bases
TTGCGTTCTCCCCCTGTCCTTTTGCTTTTGCTGGCGCTGCTGACCCCGGGCGCGGCGGCACAGGCAGTACCGCCCGCCGT
GCAGGGTGCGCCTGCCCCGGCGAGTCCCGCTCGGCTCACCCTGGCCAATGTGCTCACGCGGCTGCGCGCTGGTCCCGGTT
GGCGCGCTGCCGATCTTCAGTACCGTCAAGCGGCGCTGACGCTGGAACGCGCGCGCGTGCAGGCCGGACTGAATGTGACC
GTGGGGGCCGATGTGGGCGCCGTCAAGATCCCCCTATCCACGGGTGACCTAACACTCAACACCACCGTGAATGCGCAGGC
TTCGGCCAGCGTGCTGCCCTGGTCGCCTGCATTGGAAGCGGTTCGCAGTGCCGAGCGGGCCCTGGCCAGCGCCGCGGCCG
AGCTGCGCGCCACCCAGCAAACCCTCGCGGTGAACGCTGTGCAGGCGTACTACGCGGCCCGGAATGCTGCGGCGAGTCTC
GCGCTGGCCGACGCACAACTTGCCCTCAGTCAGCGGCAGTTGGCCGTTGCGCAGGCACAGCGGGCGGCGGGCGTGCTGAC
CGAGGAGGGCCTGCTGGCCCGCCAGGACGCCCTGGCCGATGCTCAAGCTGCCCAGCGGCAGGCCCGCACGAACGTGGACC
TGGCGGCACGGGGACTGGCGAACCTACTCGGCCAATCCGTGACGTTGCCTGCGGACGCTGAGGCTTTTGGTCCCCTCCCT
CCCGTGCCACAAAGCCCGAGTTCGGCGGAGGCGCTGGTGACCCGTGCCCTGGCCACTCGCCCCGAGGTGGCCCGGGCGCA
GAACGACCTCGCAGACGCGCAGGCGCAGCTGCGGGCGGCGCAGCGGGATGCCCGGCTCCCCGACCTCACTGCCAGCGTGC
AGTACGGACAATTGGCGGCCACCCAGGCCGAGACGGGCCGCGTGGTGGGCGGCAGCCTGAACGTGAAAACTGGCGTGCTG
GCCGGGCAGGTCAGCCTGCCTTTGCGTGATCCGGGCGAGCGGCCCAGTGGGCTGGCCCTCAGCCTCAGCGGCAGCTTTTC
GGTCATCGGTGGGGGCAAGGGTCCGGCGCTCGCCGCCGCCGAGGTGAGCGTGGCACTGGCTCAGGCTGCGCTGGAGAGTG
CCCGGCAAAGTGTGGACCTGGAGGTGCGGCAGCGCTCTGCCGACCTGCAGACCGCCCTCGACACCCTCGCCAGCCAACGC
GGCGCCCTCGCGCGTGCCCAGGCTGCCCTCGTCAGCACCCAGGCCCGGCTCGCAGCAGGGCTTGCTACCGAGCTGGACGT
GCAGGCGGCCCAGCTGAACGTCATGCAGACGCAACTCGCGGTAGACAACGCGACCGTCCAAGCCCATCTCGCCTCGCTGC
GCCTCGGCCAGGCCACGGGCGAACTTGACCCTACCCTCCTGATTCTCACCCCGCCCGCTCCGGAGGCCCGTCCATGA

Upstream 100 bases:

>100_bases
GTCTTGTGGCCGGGGTTGGAACCCTAACCCCGAACTCGCGTATTCCAGCGGGTAAGGAAGTCGACACTCGTTAATCTCTT
TGTCTCCCCCGAGGTGCTTC

Downstream 100 bases:

>100_bases
AGCGACTTTCTCTCACGCTTGCTCTGTTTCTTGCTGCACCCCTTGCCGCCGCTCAGACAGTGAGCCTCACGTTGCCGGAT
GCCGTCAGCCGCGCGTTGGC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MRSPPVLLLLLALLTPGAAAQAVPPAVQGAPAPASPARLTLANVLTRLRAGPGWRAADLQYRQAALTLERARVQAGLNVT
VGADVGAVKIPLSTGDLTLNTTVNAQASASVLPWSPALEAVRSAERALASAAAELRATQQTLAVNAVQAYYAARNAAASL
ALADAQLALSQRQLAVAQAQRAAGVLTEEGLLARQDALADAQAAQRQARTNVDLAARGLANLLGQSVTLPADAEAFGPLP
PVPQSPSSAEALVTRALATRPEVARAQNDLADAQAQLRAAQRDARLPDLTASVQYGQLAATQAETGRVVGGSLNVKTGVL
AGQVSLPLRDPGERPSGLALSLSGSFSVIGGGKGPALAAAEVSVALAQAALESARQSVDLEVRQRSADLQTALDTLASQR
GALARAQAALVSTQARLAAGLATELDVQAAQLNVMQTQLAVDNATVQAHLASLRLGQATGELDPTLLILTPPAPEARP

Sequences:

>Translated_478_residues
MRSPPVLLLLLALLTPGAAAQAVPPAVQGAPAPASPARLTLANVLTRLRAGPGWRAADLQYRQAALTLERARVQAGLNVT
VGADVGAVKIPLSTGDLTLNTTVNAQASASVLPWSPALEAVRSAERALASAAAELRATQQTLAVNAVQAYYAARNAAASL
ALADAQLALSQRQLAVAQAQRAAGVLTEEGLLARQDALADAQAAQRQARTNVDLAARGLANLLGQSVTLPADAEAFGPLP
PVPQSPSSAEALVTRALATRPEVARAQNDLADAQAQLRAAQRDARLPDLTASVQYGQLAATQAETGRVVGGSLNVKTGVL
AGQVSLPLRDPGERPSGLALSLSGSFSVIGGGKGPALAAAEVSVALAQAALESARQSVDLEVRQRSADLQTALDTLASQR
GALARAQAALVSTQARLAAGLATELDVQAAQLNVMQTQLAVDNATVQAHLASLRLGQATGELDPTLLILTPPAPEARP
>Mature_478_residues
MRSPPVLLLLLALLTPGAAAQAVPPAVQGAPAPASPARLTLANVLTRLRAGPGWRAADLQYRQAALTLERARVQAGLNVT
VGADVGAVKIPLSTGDLTLNTTVNAQASASVLPWSPALEAVRSAERALASAAAELRATQQTLAVNAVQAYYAARNAAASL
ALADAQLALSQRQLAVAQAQRAAGVLTEEGLLARQDALADAQAAQRQARTNVDLAARGLANLLGQSVTLPADAEAFGPLP
PVPQSPSSAEALVTRALATRPEVARAQNDLADAQAQLRAAQRDARLPDLTASVQYGQLAATQAETGRVVGGSLNVKTGVL
AGQVSLPLRDPGERPSGLALSLSGSFSVIGGGKGPALAAAEVSVALAQAALESARQSVDLEVRQRSADLQTALDTLASQR
GALARAQAALVSTQARLAAGLATELDVQAAQLNVMQTQLAVDNATVQAHLASLRLGQATGELDPTLLILTPPAPEARP

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48665; Mature: 48665

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPPVLLLLLALLTPGAAAQAVPPAVQGAPAPASPARLTLANVLTRLRAGPGWRAADLQ
CCCCHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
YRQAALTLERARVQAGLNVTVGADVGAVKIPLSTGDLTLNTTVNAQASASVLPWSPALEA
HHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHH
VRSAERALASAAAELRATQQTLAVNAVQAYYAARNAAASLALADAQLALSQRQLAVAQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGVLTEEGLLARQDALADAQAAQRQARTNVDLAARGLANLLGQSVTLPADAEAFGPLP
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHCCCCC
PVPQSPSSAEALVTRALATRPEVARAQNDLADAQAQLRAAQRDARLPDLTASVQYGQLAA
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
TQAETGRVVGGSLNVKTGVLAGQVSLPLRDPGERPSGLALSLSGSFSVIGGGKGPALAAA
CCCCCCEEECCCCCEECCEEEEEEECCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHH
EVSVALAQAALESARQSVDLEVRQRSADLQTALDTLASQRGALARAQAALVSTQARLAAG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
LATELDVQAAQLNVMQTQLAVDNATVQAHLASLRLGQATGELDPTLLILTPPAPEARP
CHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRSPPVLLLLLALLTPGAAAQAVPPAVQGAPAPASPARLTLANVLTRLRAGPGWRAADLQ
CCCCHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
YRQAALTLERARVQAGLNVTVGADVGAVKIPLSTGDLTLNTTVNAQASASVLPWSPALEA
HHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHH
VRSAERALASAAAELRATQQTLAVNAVQAYYAARNAAASLALADAQLALSQRQLAVAQAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGVLTEEGLLARQDALADAQAAQRQARTNVDLAARGLANLLGQSVTLPADAEAFGPLP
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHCCCCC
PVPQSPSSAEALVTRALATRPEVARAQNDLADAQAQLRAAQRDARLPDLTASVQYGQLAA
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
TQAETGRVVGGSLNVKTGVLAGQVSLPLRDPGERPSGLALSLSGSFSVIGGGKGPALAAA
CCCCCCEEECCCCCEECCEEEEEEECCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHH
EVSVALAQAALESARQSVDLEVRQRSADLQTALDTLASQRGALARAQAALVSTQARLAAG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
LATELDVQAAQLNVMQTQLAVDNATVQAHLASLRLGQATGELDPTLLILTPPAPEARP
CHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA