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The map label for this gene is emrA [H]

Identifier: 94986216

GI number: 94986216

Start: 2228407

End: 2229693

Strand: Reverse

Name: emrA [H]

Synonym: Dgeo_2117

Alternate gene names: 94986216

Gene position: 2229693-2228407 (Counterclockwise)

Preceding gene: 94986217

Following gene: 94986215

Centisome position: 90.37

GC content: 70.71

Gene sequence:

>1287_bases
ATGACCCGTTTCTCCCTCCGAGCCGCCCTGCCCCTCACCTTGCTGTTGCTGCTGGCGGCCTGCTCGCCTGCTGGAAAAAC
AGAAGAGCAGTCCGCTGCGCAGACGACCACCACCCAGAACAACCTGGACGTAGCCCCCGCCAAGACCACGGCGCTGGCGG
TGCAGACGGTGCCCGCCGTGAGGGGGAGCCTGACGGTTCAGCGCACCGTCACCGCCACCCTCAAGGCCGACCGTGATAGC
CAGGTGGCCGCGCAGACGGGAGGCACCGTCATCCGTGTTCTGGCGCAGGAGGGCGAACACGTCCGCGCCGGCCAGGTCGT
CGTGCAGCTCGACGACACGCAGCAGCGGCAGGCGCTTGACAACGCCCGCTTGCAGCTGCGGCAGGCCCAGATCAACCTCG
ACCAGACCCGCACAAACACCAGCCAGGCCACAGCTTCCCTTCAGGCTGCGGTCCAGGCTGCCGAGGCCAATCTCCAGAAG
GCCCGGCAGGACGCGGCCAGCGCGGCCAATCTCTACGCGCTGGGCGGCATCAGCCAGGCGGACCTCGCGGCCGCTCGCAG
CGCGCAGGCGCAGGCGGAAAGCCAGCTTGCGCAGGCCCGCAACAACCTCGCGCAAAACGGCCGGGGCGGACAGGGGAGCC
TCGCCCTGCTCCAGGTCCAGGTGGAAACCGCGCAGGCGGGTGTGCGCCAGGCCGAGGAGAACCTGGCCCGGACGCAGGTG
CGGGCGCCTTTTGCAGGTGTTCTCGCCTCGCTCGCTGTGGATGAGGGCGAATTCGCTGCGCAGGGCAGCCCGGTTTTTCG
CCTGGTGGGGGAGGGGAGCCTCAAGGCCACCTTCAACGTGACACCGGGAGACGCGCGCGCCCTGACGCCAGGCACGCAGG
TGAACTTGGACTACGGCGGCCAGACCTACATTGCTACCGTGCAGGACGCCAGCGGGGTCGCCGGCAGCGACCGGTTGGTG
CCCGTGACCGTGCGGGTAGGCGGCGGCGCGAACCTCCCGGTTGGCGGCACCGCGCAGGTCCGCTACCGCGCGGCCCTGGG
AAACGGGGTGCTGGTGCCCACCCCCGCGATCCAGGTGGACGGCGGCGAGAACGCGGTGTACGTGGCCGAGGACGGCGTGG
CGCGCCGCGTCCCCGTCACCGTTGTGGCCGAGGCGCAGGGACGGGTGGCGGTGCGTGGCCTGGACGCCGGAGCCCACGTG
ATCTCGCCAGTGCCCGCTAGCCTCCAGGACGGAGCGAGCATTCGGGAGACGGTTCGGCCCGACCAGGGAAGAGGGGAGAC
ACCATGA

Upstream 100 bases:

>100_bases
CTTTTGGCGTGACTCAGGCACAGGACAACCTCTGGCGGGCCCTGGCCGCGCTCTCCGTTGCGTCGGGAACGGACGTGACC
GGACTGGTGAGGTGAGGCCC

Downstream 100 bases:

>100_bases
GTACCCACGACCCGCCGGAATTCAGCGCCCCACGCGGCACCCTGCCCGATGGCACCCCTGAACCCGCCGTACATCCCGCC
GTGCGCTTCAGCGTGCGCAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTRFSLRAALPLTLLLLLAACSPAGKTEEQSAAQTTTTQNNLDVAPAKTTALAVQTVPAVRGSLTVQRTVTATLKADRDS
QVAAQTGGTVIRVLAQEGEHVRAGQVVVQLDDTQQRQALDNARLQLRQAQINLDQTRTNTSQATASLQAAVQAAEANLQK
ARQDAASAANLYALGGISQADLAAARSAQAQAESQLAQARNNLAQNGRGGQGSLALLQVQVETAQAGVRQAEENLARTQV
RAPFAGVLASLAVDEGEFAAQGSPVFRLVGEGSLKATFNVTPGDARALTPGTQVNLDYGGQTYIATVQDASGVAGSDRLV
PVTVRVGGGANLPVGGTAQVRYRAALGNGVLVPTPAIQVDGGENAVYVAEDGVARRVPVTVVAEAQGRVAVRGLDAGAHV
ISPVPASLQDGASIRETVRPDQGRGETP

Sequences:

>Translated_428_residues
MTRFSLRAALPLTLLLLLAACSPAGKTEEQSAAQTTTTQNNLDVAPAKTTALAVQTVPAVRGSLTVQRTVTATLKADRDS
QVAAQTGGTVIRVLAQEGEHVRAGQVVVQLDDTQQRQALDNARLQLRQAQINLDQTRTNTSQATASLQAAVQAAEANLQK
ARQDAASAANLYALGGISQADLAAARSAQAQAESQLAQARNNLAQNGRGGQGSLALLQVQVETAQAGVRQAEENLARTQV
RAPFAGVLASLAVDEGEFAAQGSPVFRLVGEGSLKATFNVTPGDARALTPGTQVNLDYGGQTYIATVQDASGVAGSDRLV
PVTVRVGGGANLPVGGTAQVRYRAALGNGVLVPTPAIQVDGGENAVYVAEDGVARRVPVTVVAEAQGRVAVRGLDAGAHV
ISPVPASLQDGASIRETVRPDQGRGETP
>Mature_427_residues
TRFSLRAALPLTLLLLLAACSPAGKTEEQSAAQTTTTQNNLDVAPAKTTALAVQTVPAVRGSLTVQRTVTATLKADRDSQ
VAAQTGGTVIRVLAQEGEHVRAGQVVVQLDDTQQRQALDNARLQLRQAQINLDQTRTNTSQATASLQAAVQAAEANLQKA
RQDAASAANLYALGGISQADLAAARSAQAQAESQLAQARNNLAQNGRGGQGSLALLQVQVETAQAGVRQAEENLARTQVR
APFAGVLASLAVDEGEFAAQGSPVFRLVGEGSLKATFNVTPGDARALTPGTQVNLDYGGQTYIATVQDASGVAGSDRLVP
VTVRVGGGANLPVGGTAQVRYRAALGNGVLVPTPAIQVDGGENAVYVAEDGVARRVPVTVVAEAQGRVAVRGLDAGAHVI
SPVPASLQDGASIRETVRPDQGRGETP

Specific function: The emr locus confers resistance to substances of high hydrophobicity. EmrA probably participate in a transport system to extrude toxins and drugs from the cell [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43985; Mature: 43853

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFSLRAALPLTLLLLLAACSPAGKTEEQSAAQTTTTQNNLDVAPAKTTALAVQTVPAV
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEECCCCCEEEEEEECCHH
RGSLTVQRTVTATLKADRDSQVAAQTGGTVIRVLAQEGEHVRAGQVVVQLDDTQQRQALD
CCCEEEEEEEEEEEECCCCCHHHHHCCCEEEEEEECCCCEEEECEEEEEECCCHHHHHHH
NARLQLRQAQINLDQTRTNTSQATASLQAAVQAAEANLQKARQDAASAANLYALGGISQA
HHHHEEEHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHH
DLAAARSAQAQAESQLAQARNNLAQNGRGGQGSLALLQVQVETAQAGVRQAEENLARTQV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
RAPFAGVLASLAVDEGEFAAQGSPVFRLVGEGSLKATFNVTPGDARALTPGTQVNLDYGG
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCEEECCCCEEEEECCC
QTYIATVQDASGVAGSDRLVPVTVRVGGGANLPVGGTAQVRYRAALGNGVLVPTPAIQVD
EEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCEECCCCEEEEC
GGENAVYVAEDGVARRVPVTVVAEAQGRVAVRGLDAGAHVISPVPASLQDGASIRETVRP
CCCCEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCCEECCCCCCCCCCCHHHHHCCC
DQGRGETP
CCCCCCCC
>Mature Secondary Structure 
TRFSLRAALPLTLLLLLAACSPAGKTEEQSAAQTTTTQNNLDVAPAKTTALAVQTVPAV
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEECCCCCEEEEEEECCHH
RGSLTVQRTVTATLKADRDSQVAAQTGGTVIRVLAQEGEHVRAGQVVVQLDDTQQRQALD
CCCEEEEEEEEEEEECCCCCHHHHHCCCEEEEEEECCCCEEEECEEEEEECCCHHHHHHH
NARLQLRQAQINLDQTRTNTSQATASLQAAVQAAEANLQKARQDAASAANLYALGGISQA
HHHHEEEHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHH
DLAAARSAQAQAESQLAQARNNLAQNGRGGQGSLALLQVQVETAQAGVRQAEENLARTQV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHH
RAPFAGVLASLAVDEGEFAAQGSPVFRLVGEGSLKATFNVTPGDARALTPGTQVNLDYGG
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCCCCEEECCCCEEEEECCC
QTYIATVQDASGVAGSDRLVPVTVRVGGGANLPVGGTAQVRYRAALGNGVLVPTPAIQVD
EEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCEECCCCEEEEC
GGENAVYVAEDGVARRVPVTVVAEAQGRVAVRGLDAGAHVISPVPASLQDGASIRETVRP
CCCCEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCCEECCCCCCCCCCCHHHHHCCC
DQGRGETP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]