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The map label for this gene is atpD

Identifier: 94986144

GI number: 94986144

Start: 2152033

End: 2152701

Strand: Reverse

Name: atpD

Synonym: Dgeo_2045

Alternate gene names: 94986144

Gene position: 2152701-2152033 (Counterclockwise)

Preceding gene: 94986145

Following gene: 94986140

Centisome position: 87.25

GC content: 63.08

Gene sequence:

>669_bases
ATGGCAGGACAGATCAGTCCCACCCGCAGTGCCCTCCTGGCCAGCAAGGCCAGCCTCAAGACGGCAACCAGCGGCGCAGA
CCTGCTGAAACGCAAGCGGGACGCGCTGATTGGTGAATTTTTCGCGCTGGTAAAGGATGCCCTCGCGGCGCGCGAACAGC
TCGCTGGGGTCAGCAAGGGTGCCTACACCAGCTTGTTCGGTGCCAAAGCATGGGACAGCCCTGAGGCTGTAGAGAGCCTC
AGTCTGGCGGGGACCAGCGACTACGCCGTCGATATGCAGATCGAGAGCATCTACGGGGTGAAGGTGCCGCGTATCAAGAT
TCCCGAGCGCCAGGCCGCTGCCGCCTTCAGCCCGATCAACGTCGGCGCCCGGACCATTCAGGCCGCGACCGATTTCGGGA
CCGTTCTGGAAGCCATTGTGCGCGTGGCCGCGACCGAGACGAAGCTGCGCCGCATTGGTGAGGAAATCAAGAAGACCAGT
CGGCGCGTGAACGCGCTGGAACAGGTCGTGATCCCCGGCATCCGCGACGACATCCGTTTCATTCGCGGCGTGCTCGACCA
GCGCGAGCGCGAAGAGAGCTTCCGCCTGAAGAAGATCAAGGCGAAACTCGAACGCGAGAAGAACAAGGAAAACGCCCAAG
CCGGGCAGCATGGCAGCGCCGCTGACTGA

Upstream 100 bases:

>100_bases
CGAGATGTGGCGGGGGAACCGGATCTAAGGTTGTCGGCGGTCGGGTGGAGGTGACTCTCCAGCGACCGCTCACAACCCCA
CCGCCAAAGGAGGTGGAATC

Downstream 100 bases:

>100_bases
GCAGGACTCGTCCGAAGACCGCCCCACAGGGGGCGGTTTTTTTCCGTTCTGGTGTGCCTGGTGTGTGTGTGGATGTACCC
GCGCGTGGCCGAGCTTTCTG

Product: V-type ATPase, D subunit

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MAGQISPTRSALLASKASLKTATSGADLLKRKRDALIGEFFALVKDALAAREQLAGVSKGAYTSLFGAKAWDSPEAVESL
SLAGTSDYAVDMQIESIYGVKVPRIKIPERQAAAAFSPINVGARTIQAATDFGTVLEAIVRVAATETKLRRIGEEIKKTS
RRVNALEQVVIPGIRDDIRFIRGVLDQREREESFRLKKIKAKLEREKNKENAQAGQHGSAAD

Sequences:

>Translated_222_residues
MAGQISPTRSALLASKASLKTATSGADLLKRKRDALIGEFFALVKDALAAREQLAGVSKGAYTSLFGAKAWDSPEAVESL
SLAGTSDYAVDMQIESIYGVKVPRIKIPERQAAAAFSPINVGARTIQAATDFGTVLEAIVRVAATETKLRRIGEEIKKTS
RRVNALEQVVIPGIRDDIRFIRGVLDQREREESFRLKKIKAKLEREKNKENAQAGQHGSAAD
>Mature_221_residues
AGQISPTRSALLASKASLKTATSGADLLKRKRDALIGEFFALVKDALAAREQLAGVSKGAYTSLFGAKAWDSPEAVESLS
LAGTSDYAVDMQIESIYGVKVPRIKIPERQAAAAFSPINVGARTIQAATDFGTVLEAIVRVAATETKLRRIGEEIKKTSR
RVNALEQVVIPGIRDDIRFIRGVLDQREREESFRLKKIKAKLEREKNKENAQAGQHGSAAD

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family

Homologues:

Organism=Homo sapiens, GI7706757, Length=215, Percent_Identity=29.7674418604651, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17553636, Length=220, Percent_Identity=33.6363636363636, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320784, Length=224, Percent_Identity=31.6964285714286, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20128937, Length=213, Percent_Identity=29.1079812206573, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355551, Length=213, Percent_Identity=30.0469483568075, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129907, Length=206, Percent_Identity=29.6116504854369, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATD_DEIGD (Q1IWP5)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_605508.1
- STRING:   Q1IWP5
- GeneID:   4058391
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_2045
- NMPDR:   fig|68909.1.peg.2229
- eggNOG:   COG1394
- HOGENOM:   HBG732046
- OMA:   INVGART
- PhylomeDB:   Q1IWP5
- ProtClustDB:   CLSK444671
- BioCyc:   DGEO319795:DGEO_2045-MONOMER
- HAMAP:   MF_00271
- InterPro:   IPR002699
- PANTHER:   PTHR11671
- TIGRFAMs:   TIGR00309

Pfam domain/function: PF01813 ATP-synt_D

EC number: 3.6.3.14

Molecular weight: Translated: 24065; Mature: 23934

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQISPTRSALLASKASLKTATSGADLLKRKRDALIGEFFALVKDALAAREQLAGVSKG
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AYTSLFGAKAWDSPEAVESLSLAGTSDYAVDMQIESIYGVKVPRIKIPERQAAAAFSPIN
HHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCEECCCHHHHHHCCCHH
VGARTIQAATDFGTVLEAIVRVAATETKLRRIGEEIKKTSRRVNALEQVVIPGIRDDIRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IRGVLDQREREESFRLKKIKAKLEREKNKENAQAGQHGSAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCC
>Mature Secondary Structure 
AGQISPTRSALLASKASLKTATSGADLLKRKRDALIGEFFALVKDALAAREQLAGVSKG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AYTSLFGAKAWDSPEAVESLSLAGTSDYAVDMQIESIYGVKVPRIKIPERQAAAAFSPIN
HHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCEECCCHHHHHHCCCHH
VGARTIQAATDFGTVLEAIVRVAATETKLRRIGEEIKKTSRRVNALEQVVIPGIRDDIRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IRGVLDQREREESFRLKKIKAKLEREKNKENAQAGQHGSAAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA