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The map label for this gene is nrdR

Identifier: 94986132

GI number: 94986132

Start: 2141382

End: 2141834

Strand: Reverse

Name: nrdR

Synonym: Dgeo_2033

Alternate gene names: 94986132

Gene position: 2141834-2141382 (Counterclockwise)

Preceding gene: 94986133

Following gene: 94986124

Centisome position: 86.81

GC content: 62.69

Gene sequence:

>453_bases
ATGAAGTGTCCTTACTGCTCTGCTCCCGATTCCAGGGTCGTCAACTCACGCCCCAGTGACGACGGAGCCAGCATTCGGCG
CCGCCGCGAGTGCCTGCGCTGCAACCGGAGATTTACCACCTACGAGCGTGCCCAGCTTGAACCGCTGATGGTGCTTAAGC
GCGGCGGCCAGCGCGAGGCGTTCAACCCCGATAAGCTTTTGCGCGGCCTGATCCTCGCCACCGAAAAACGCCCGGTTGAC
CCCGAGCAGTTGCGAGCCTTTGCCTATGGCTTCGAGGACGAGGTCCAGGCCTCTGAGATCACCTCGGAAGAGATCGGGCG
CCGCGCGATGACCTTCCTCCGCCCGCTTGACGACGTGGCCTATATCCGCTTTGCCAGCGTCTACCGCGATTTTGACAGCC
TCGAGCGCTTCATCGAGGAGATTCAGGGGCTCAAGGGCCGGGGCGAGGACTAA

Upstream 100 bases:

>100_bases
GGCAGTGCCCCCGCGTGAAAGCGCGGACAAGCTCGCCATTCCAGGGCTGGTTGGGGCCGCGCAGAGGGCGCGAGGAGAGA
TGGCCCTTACTGGAGTCGCT

Downstream 100 bases:

>100_bases
GTCCCGCAGCCACCACCCCCGCGCGGGGCGGGGGAGAGCGGCGGTTTATCTGCGCCTCAGCCAGTGCTGCAAGGTGCCCA
CCACGCCGCGGCGGAAGAAC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKCPYCSAPDSRVVNSRPSDDGASIRRRRECLRCNRRFTTYERAQLEPLMVLKRGGQREAFNPDKLLRGLILATEKRPVD
PEQLRAFAYGFEDEVQASEITSEEIGRRAMTFLRPLDDVAYIRFASVYRDFDSLERFIEEIQGLKGRGED

Sequences:

>Translated_150_residues
MKCPYCSAPDSRVVNSRPSDDGASIRRRRECLRCNRRFTTYERAQLEPLMVLKRGGQREAFNPDKLLRGLILATEKRPVD
PEQLRAFAYGFEDEVQASEITSEEIGRRAMTFLRPLDDVAYIRFASVYRDFDSLERFIEEIQGLKGRGED
>Mature_150_residues
MKCPYCSAPDSRVVNSRPSDDGASIRRRRECLRCNRRFTTYERAQLEPLMVLKRGGQREAFNPDKLLRGLILATEKRPVD
PEQLRAFAYGFEDEVQASEITSEEIGRRAMTFLRPLDDVAYIRFASVYRDFDSLERFIEEIQGLKGRGED

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=45.2702702702703, Blast_Score=127, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_DEIGD (Q1IWQ7)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_605496.1
- STRING:   Q1IWQ7
- GeneID:   4058379
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_2033
- NMPDR:   fig|68909.1.peg.2217
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q1IWQ7
- ProtClustDB:   PRK00464
- BioCyc:   DGEO319795:DGEO_2033-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17399; Mature: 17399

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPYCSAPDSRVVNSRPSDDGASIRRRRECLRCNRRFTTYERAQLEPLMVLKRGGQREA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCC
FNPDKLLRGLILATEKRPVDPEQLRAFAYGFEDEVQASEITSEEIGRRAMTFLRPLDDVA
CCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRFASVYRDFDSLERFIEEIQGLKGRGED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKCPYCSAPDSRVVNSRPSDDGASIRRRRECLRCNRRFTTYERAQLEPLMVLKRGGQREA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCC
FNPDKLLRGLILATEKRPVDPEQLRAFAYGFEDEVQASEITSEEIGRRAMTFLRPLDDVA
CCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIRFASVYRDFDSLERFIEEIQGLKGRGED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA