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The map label for this gene is rnhA [H]

Identifier: 94986068

GI number: 94986068

Start: 2071676

End: 2072131

Strand: Reverse

Name: rnhA [H]

Synonym: Dgeo_1969

Alternate gene names: 94986068

Gene position: 2072131-2071676 (Counterclockwise)

Preceding gene: 94986084

Following gene: 94986067

Centisome position: 83.99

GC content: 66.01

Gene sequence:

>456_bases
GTGCCGGTTGCCGGGGAGGTGGTGGACCTCTACAGCGACGGCGCCTGCGACACGGCAGCTGGGCACGGCGGCTGGGCCAC
CATTCTGAGATACCGGGGCAAGGAACTGGTCCTGAGCGGCCGTGAGCGGGACACCACCAACAACCGCATGGAGCTGCTCG
GCCTGCTGGAGGGACTCAAGGTGCTCAAGCGTCCCTGCCAGGTCCGGGTCGTCACCGACAGCCAGTACCTCCGCAAAGCC
TTTACCGACGGCTGGATTCTGAAGTGGCAGCGCAACGGCTGGAAGACGGCGGGGGGCGAGCCGGTGAAAAATCAGGACCT
CTGGGAGGAGCTGATCGCCCAGGCCCAAAGGCATGCCCTGACCTTTGTGTGGGTGCGCGGCCACAACGGACACGGCGAGA
ACGAGCGGGTAGACCGACTCGCGGTGGAGGAGCGCAAGAAACTCCGGCAGGGATGA

Upstream 100 bases:

>100_bases
GCGCCCCGGCGGGAAACCCAACTTCAGGATGTCCCCCGCAAGAAAAGCCCGGGACGCCGCGCGTGACCTGCTCCCCATCA
AGGCGGGCATCCAGCCAGCG

Downstream 100 bases:

>100_bases
GGGCGCGGGTGCAGCCGCAGCGTCAGGCCGGGAGCACCCGCCACTCGCTCCCCCGCCATCTGACGGATGTTCCGCGCGTC
CCACGCAGCCTACGCTGCCT

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MPVAGEVVDLYSDGACDTAAGHGGWATILRYRGKELVLSGRERDTTNNRMELLGLLEGLKVLKRPCQVRVVTDSQYLRKA
FTDGWILKWQRNGWKTAGGEPVKNQDLWEELIAQAQRHALTFVWVRGHNGHGENERVDRLAVEERKKLRQG

Sequences:

>Translated_151_residues
MPVAGEVVDLYSDGACDTAAGHGGWATILRYRGKELVLSGRERDTTNNRMELLGLLEGLKVLKRPCQVRVVTDSQYLRKA
FTDGWILKWQRNGWKTAGGEPVKNQDLWEELIAQAQRHALTFVWVRGHNGHGENERVDRLAVEERKKLRQG
>Mature_150_residues
PVAGEVVDLYSDGACDTAAGHGGWATILRYRGKELVLSGRERDTTNNRMELLGLLEGLKVLKRPCQVRVVTDSQYLRKAF
TDGWILKWQRNGWKTAGGEPVKNQDLWEELIAQAQRHALTFVWVRGHNGHGENERVDRLAVEERKKLRQG

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=134, Percent_Identity=49.2537313432836, Blast_Score=135, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI115532542, Length=154, Percent_Identity=32.4675324675325, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 17150; Mature: 17019

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVAGEVVDLYSDGACDTAAGHGGWATILRYRGKELVLSGRERDTTNNRMELLGLLEGLK
CCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VLKRPCQVRVVTDSQYLRKAFTDGWILKWQRNGWKTAGGEPVKNQDLWEELIAQAQRHAL
HHCCCCEEEEEECHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCEE
TFVWVRGHNGHGENERVDRLAVEERKKLRQG
EEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PVAGEVVDLYSDGACDTAAGHGGWATILRYRGKELVLSGRERDTTNNRMELLGLLEGLK
CCCCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VLKRPCQVRVVTDSQYLRKAFTDGWILKWQRNGWKTAGGEPVKNQDLWEELIAQAQRHAL
HHCCCCEEEEEECHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCEE
TFVWVRGHNGHGENERVDRLAVEERKKLRQG
EEEEEECCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA