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The map label for this gene is maoC [H]

Identifier: 94986013

GI number: 94986013

Start: 2017004

End: 2019091

Strand: Reverse

Name: maoC [H]

Synonym: Dgeo_1913

Alternate gene names: 94986013

Gene position: 2019091-2017004 (Counterclockwise)

Preceding gene: 94986015

Following gene: 94986012

Centisome position: 81.84

GC content: 67.34

Gene sequence:

>2088_bases
ATGACCACCCTCCCCACCCCCGATATCCTCCGCCCCGCCTCCTACGTCTACGGCACCTGGCACACTGCCCCCGAAGGTCA
GACCCTCTACGACGCCGTGTATGGCCGCCCCGTCGCCGTCATCTCCTCTGAGGGAGTGGATTTCGCGGCGGCTTTGCGCT
ACGGGCGCGAGGTGGGCGGTCCGGCGCTGCGCCGGCTGACCTTCCACACGCGGGCACGGTTGCTGCGGGCACTGGCAACC
TACCTGCTGGAGCGCAAGGAGGACTATTACCGGCTCAGCCTGCTGACCGGCGCGACCCGCCGTGACGGCTGGGTGGACAT
CGAGGGCGGCATTGGGACGCTGTTGAGCTACGCGAGCATGGCCCGCCGCGAGCTGCCGGACGAGCGGTTTCTCCCCGACG
GCAAGGTCGAACAGCTCGGCAAGGGCGGCACCTTCGCAGGCCGTCACCTCCTGGTGCCGCGTGAGGGCGTGGCGGTGCAG
ATCAACGCCTACAACTTCCCGGTCTGGGGAATGCTGGAAAAACTTGCCCCGGCCTTCATCGCTGGGATGCCCAGCCTGGT
CAAGCCCGCACCGCAGACGGCTTACCTTGCTGAGCGGGTGGTGCGTGACATCATCGCTTCGGGCCTGCTGCCGGAAGGGG
CACTGCAACTGGTGACAGGAGAGCCGGGCGACCTGCTCGACCACCTGGAGGAGCAGGACCTGGTGGCCTTTACGGGGTCG
GCGGCCACAGCGGCGAAGCTGCGGGTTCATCCCAACCTTGTCGCGCGCAACGTGCCCTTCAATACCGAGGCCGACAGTCT
GAATGCCTCCGTGTTGGGCCTGACGGTACGTCCCGAGGACCCGGAGTTCGCCCTCTATGTGCGCGAGGTGGCCCGCGAGA
TGACGGGCAAGGCCGGGCAGAAATGCACCGCGATCCGCCGCGCAATCGTTCCCCGCGACCGGGTGGAGGAGGTTGTGGCG
GCGCTGAGGCAGGAACTGAGCAAGGTCACTATCGGTGATCCCGCCCGTGACGACGTGCGGATGGGGGCGCTTGTCAGCAC
TGAGCAGCGGGAACGGGTACGTGCGACGCTGGCGGCGCTACAACGCGAAGCCCAACTGGTGATCGGCGGCGAGGAACGCG
AACTGCTGGGCGGCGACCGTGAGAAGGGCGCCTTCCTCGACCCCACCCTGTTGCTGTGTGAGTCGCCCCTCACGGCCCGC
GGTCCGCACGAGCTGGAAGCCTTCGGCCCGGTGGCGACCCTCCTTCCCTACGACACCTTGGAGGAAGCCGCGTACCTCAC
CCGAATGGGCCGCGGCAGCCTGGCAGGAAGCGTCGTCACCCATGACCGTGCGGAGGCCGCCGAACTCGTGATGGGCATGG
CGAGCAGCCACGGGCGAATCCTGATCCTCAACCGCGAGAACGCGAAGGAAAGCACCGGGCACGGCTCGCCCCTCCCGCAG
CTGCTCCACGGGGGTCCCGGGCGCGCGGGTGGCGGCGCGGAGCTGGCGGGAATTTCTGGCATCAAACACCACATGAATAA
GGTGGCCGTGCAGGCCGATCCAACCACCCTCGCCGCCATCACGCACGAGTACGTGCCCGGCGCAGAGGTCAAGGAAGACG
TGATCCACCCCTTCCGCAAATCTTTTGATGAAATCCAGGTCGGCGACAGCCTGCTCACGCACCGCCGCACCGTCACCGAG
GCGGACATCGTCAACTTCGCGGCCCTGACAGGCGACCACTTCTATGCCCACGTGGACGAGATCGGCGCGCGCGAAGGCAT
CTTCGGGAGGCGGGTCGCCCACGGCTACTTCCTGATCTCTGCCGCTGCCGGACAGTTCGTGTGGCCTGCGCCCGGCCCGG
TGTTGGCGAACTACGGCCTGGAAAACCTGCGCTTTATCACCCCGGTCGGCATCGGGGACACCATCCGCACCCGCCTCACC
TGCAAGCGCAAGATTCGCAAGGACCTGCGCCCCGGCGAGACCCGTCCGACGGGGGTTGTCGAGTGGCACGCCGAGATCAC
CAACCAGCGGGATGAACTGGTGGCGACCTACGACATCCTGACGCTGGTAGAACGTGCCCCCGACGCGGCGGACAACCTCA
CCGTCTGA

Upstream 100 bases:

>100_bases
AGCGTCCGTGCGACCACCTGACCGGCTCGCTTCATCCCCTCCAGGTCGCGCGCGTTGCCAATTGTCATACGTGATTCTAG
CTCAGCCTCAAGGAGTTCCT

Downstream 100 bases:

>100_bases
CCCTTTTTTTCACCCGGGCCGGACAGCTTTTTCGGTGTCCGGTCCGCTTCCTTAGCGAAAGATCATGGCCCAACGTCAAT
ATCCTTTGTTGGGGTGGGCT

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MTTLPTPDILRPASYVYGTWHTAPEGQTLYDAVYGRPVAVISSEGVDFAAALRYGREVGGPALRRLTFHTRARLLRALAT
YLLERKEDYYRLSLLTGATRRDGWVDIEGGIGTLLSYASMARRELPDERFLPDGKVEQLGKGGTFAGRHLLVPREGVAVQ
INAYNFPVWGMLEKLAPAFIAGMPSLVKPAPQTAYLAERVVRDIIASGLLPEGALQLVTGEPGDLLDHLEEQDLVAFTGS
AATAAKLRVHPNLVARNVPFNTEADSLNASVLGLTVRPEDPEFALYVREVAREMTGKAGQKCTAIRRAIVPRDRVEEVVA
ALRQELSKVTIGDPARDDVRMGALVSTEQRERVRATLAALQREAQLVIGGEERELLGGDREKGAFLDPTLLLCESPLTAR
GPHELEAFGPVATLLPYDTLEEAAYLTRMGRGSLAGSVVTHDRAEAAELVMGMASSHGRILILNRENAKESTGHGSPLPQ
LLHGGPGRAGGGAELAGISGIKHHMNKVAVQADPTTLAAITHEYVPGAEVKEDVIHPFRKSFDEIQVGDSLLTHRRTVTE
ADIVNFAALTGDHFYAHVDEIGAREGIFGRRVAHGYFLISAAAGQFVWPAPGPVLANYGLENLRFITPVGIGDTIRTRLT
CKRKIRKDLRPGETRPTGVVEWHAEITNQRDELVATYDILTLVERAPDAADNLTV

Sequences:

>Translated_695_residues
MTTLPTPDILRPASYVYGTWHTAPEGQTLYDAVYGRPVAVISSEGVDFAAALRYGREVGGPALRRLTFHTRARLLRALAT
YLLERKEDYYRLSLLTGATRRDGWVDIEGGIGTLLSYASMARRELPDERFLPDGKVEQLGKGGTFAGRHLLVPREGVAVQ
INAYNFPVWGMLEKLAPAFIAGMPSLVKPAPQTAYLAERVVRDIIASGLLPEGALQLVTGEPGDLLDHLEEQDLVAFTGS
AATAAKLRVHPNLVARNVPFNTEADSLNASVLGLTVRPEDPEFALYVREVAREMTGKAGQKCTAIRRAIVPRDRVEEVVA
ALRQELSKVTIGDPARDDVRMGALVSTEQRERVRATLAALQREAQLVIGGEERELLGGDREKGAFLDPTLLLCESPLTAR
GPHELEAFGPVATLLPYDTLEEAAYLTRMGRGSLAGSVVTHDRAEAAELVMGMASSHGRILILNRENAKESTGHGSPLPQ
LLHGGPGRAGGGAELAGISGIKHHMNKVAVQADPTTLAAITHEYVPGAEVKEDVIHPFRKSFDEIQVGDSLLTHRRTVTE
ADIVNFAALTGDHFYAHVDEIGAREGIFGRRVAHGYFLISAAAGQFVWPAPGPVLANYGLENLRFITPVGIGDTIRTRLT
CKRKIRKDLRPGETRPTGVVEWHAEITNQRDELVATYDILTLVERAPDAADNLTV
>Mature_694_residues
TTLPTPDILRPASYVYGTWHTAPEGQTLYDAVYGRPVAVISSEGVDFAAALRYGREVGGPALRRLTFHTRARLLRALATY
LLERKEDYYRLSLLTGATRRDGWVDIEGGIGTLLSYASMARRELPDERFLPDGKVEQLGKGGTFAGRHLLVPREGVAVQI
NAYNFPVWGMLEKLAPAFIAGMPSLVKPAPQTAYLAERVVRDIIASGLLPEGALQLVTGEPGDLLDHLEEQDLVAFTGSA
ATAAKLRVHPNLVARNVPFNTEADSLNASVLGLTVRPEDPEFALYVREVAREMTGKAGQKCTAIRRAIVPRDRVEEVVAA
LRQELSKVTIGDPARDDVRMGALVSTEQRERVRATLAALQREAQLVIGGEERELLGGDREKGAFLDPTLLLCESPLTARG
PHELEAFGPVATLLPYDTLEEAAYLTRMGRGSLAGSVVTHDRAEAAELVMGMASSHGRILILNRENAKESTGHGSPLPQL
LHGGPGRAGGGAELAGISGIKHHMNKVAVQADPTTLAAITHEYVPGAEVKEDVIHPFRKSFDEIQVGDSLLTHRRTVTEA
DIVNFAALTGDHFYAHVDEIGAREGIFGRRVAHGYFLISAAAGQFVWPAPGPVLANYGLENLRFITPVGIGDTIRTRLTC
KRKIRKDLRPGETRPTGVVEWHAEITNQRDELVATYDILTLVERAPDAADNLTV

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777730, Length=517, Percent_Identity=26.6924564796905, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI25777732, Length=519, Percent_Identity=25.2408477842004, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI153266822, Length=454, Percent_Identity=25.9911894273128, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI115387104, Length=434, Percent_Identity=26.036866359447, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI25777724, Length=524, Percent_Identity=25.1908396946565, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI12007648, Length=293, Percent_Identity=26.2798634812287, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI25777728, Length=451, Percent_Identity=25.7206208425721, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI188035924, Length=357, Percent_Identity=23.249299719888, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI310128103, Length=357, Percent_Identity=23.249299719888, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1787653, Length=677, Percent_Identity=57.4593796159527, Blast_Score=731, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=423, Percent_Identity=26.241134751773, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787684, Length=370, Percent_Identity=27.2972972972973, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI87082295, Length=312, Percent_Identity=27.5641025641026, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1786504, Length=508, Percent_Identity=25.3937007874016, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787558, Length=456, Percent_Identity=25.8771929824561, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787715, Length=320, Percent_Identity=25.9375, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787250, Length=391, Percent_Identity=23.5294117647059, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788042, Length=407, Percent_Identity=27.027027027027, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081896, Length=307, Percent_Identity=26.0586319218241, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25143876, Length=361, Percent_Identity=26.8698060941828, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25143874, Length=361, Percent_Identity=26.8698060941828, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551164, Length=401, Percent_Identity=24.9376558603491, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562198, Length=452, Percent_Identity=26.5486725663717, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32564736, Length=351, Percent_Identity=26.7806267806268, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25144435, Length=351, Percent_Identity=26.7806267806268, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71995606, Length=272, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71995613, Length=272, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115534176, Length=366, Percent_Identity=26.775956284153, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=359, Percent_Identity=23.9554317548747, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6323822, Length=393, Percent_Identity=25.1908396946565, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323821, Length=365, Percent_Identity=23.5616438356164, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324950, Length=360, Percent_Identity=24.7222222222222, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325196, Length=297, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129399, Length=522, Percent_Identity=26.4367816091954, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281362580, Length=332, Percent_Identity=24.3975903614458, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62472918, Length=332, Percent_Identity=24.3975903614458, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62472926, Length=332, Percent_Identity=24.3975903614458, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62472936, Length=332, Percent_Identity=24.3975903614458, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356737, Length=332, Percent_Identity=24.3975903614458, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24650465, Length=452, Percent_Identity=24.3362831858407, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 75495; Mature: 75364

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLPTPDILRPASYVYGTWHTAPEGQTLYDAVYGRPVAVISSEGVDFAAALRYGREVGG
CCCCCCCHHHCCCHHEEECCCCCCCCCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCC
PALRRLTFHTRARLLRALATYLLERKEDYYRLSLLTGATRRDGWVDIEGGIGTLLSYASM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHH
ARRELPDERFLPDGKVEQLGKGGTFAGRHLLVPREGVAVQINAYNFPVWGMLEKLAPAFI
HHHHCCCHHCCCCCCHHHHCCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHH
AGMPSLVKPAPQTAYLAERVVRDIIASGLLPEGALQLVTGEPGDLLDHLEEQDLVAFTGS
HCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCEEEEECC
AATAAKLRVHPNLVARNVPFNTEADSLNASVLGLTVRPEDPEFALYVREVAREMTGKAGQ
CCCEEEEEECCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCH
KCTAIRRAIVPRDRVEEVVAALRQELSKVTIGDPARDDVRMGALVSTEQRERVRATLAAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHH
QREAQLVIGGEERELLGGDREKGAFLDPTLLLCESPLTARGPHELEAFGPVATLLPYDTL
HHCCEEEECCCCHHHCCCCCCCCCCCCCHHHEECCCCCCCCCCHHHHHCCHHHHCCHHHH
EEAAYLTRMGRGSLAGSVVTHDRAEAAELVMGMASSHGRILILNRENAKESTGHGSPLPQ
HHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHH
LLHGGPGRAGGGAELAGISGIKHHMNKVAVQADPTTLAAITHEYVPGAEVKEDVIHPFRK
HHCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEHHHHHCCCCCHHHHHHHHHHHH
SFDEIQVGDSLLTHRRTVTEADIVNFAALTGDHFYAHVDEIGAREGIFGRRVAHGYFLIS
HHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCHHHHHCCEEEEE
AAAGQFVWPAPGPVLANYGLENLRFITPVGIGDTIRTRLTCKRKIRKDLRPGETRPTGVV
ECCCCEECCCCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEE
EWHAEITNQRDELVATYDILTLVERAPDAADNLTV
EEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTLPTPDILRPASYVYGTWHTAPEGQTLYDAVYGRPVAVISSEGVDFAAALRYGREVGG
CCCCCCHHHCCCHHEEECCCCCCCCCHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCC
PALRRLTFHTRARLLRALATYLLERKEDYYRLSLLTGATRRDGWVDIEGGIGTLLSYASM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHH
ARRELPDERFLPDGKVEQLGKGGTFAGRHLLVPREGVAVQINAYNFPVWGMLEKLAPAFI
HHHHCCCHHCCCCCCHHHHCCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHH
AGMPSLVKPAPQTAYLAERVVRDIIASGLLPEGALQLVTGEPGDLLDHLEEQDLVAFTGS
HCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCCEEEEECC
AATAAKLRVHPNLVARNVPFNTEADSLNASVLGLTVRPEDPEFALYVREVAREMTGKAGQ
CCCEEEEEECCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCH
KCTAIRRAIVPRDRVEEVVAALRQELSKVTIGDPARDDVRMGALVSTEQRERVRATLAAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHH
QREAQLVIGGEERELLGGDREKGAFLDPTLLLCESPLTARGPHELEAFGPVATLLPYDTL
HHCCEEEECCCCHHHCCCCCCCCCCCCCHHHEECCCCCCCCCCHHHHHCCHHHHCCHHHH
EEAAYLTRMGRGSLAGSVVTHDRAEAAELVMGMASSHGRILILNRENAKESTGHGSPLPQ
HHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHH
LLHGGPGRAGGGAELAGISGIKHHMNKVAVQADPTTLAAITHEYVPGAEVKEDVIHPFRK
HHCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEHHHHHCCCCCHHHHHHHHHHHH
SFDEIQVGDSLLTHRRTVTEADIVNFAALTGDHFYAHVDEIGAREGIFGRRVAHGYFLIS
HHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCHHHHHCCEEEEE
AAAGQFVWPAPGPVLANYGLENLRFITPVGIGDTIRTRLTCKRKIRKDLRPGETRPTGVV
ECCCCEECCCCCCHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEE
EWHAEITNQRDELVATYDILTLVERAPDAADNLTV
EEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]