Click here to switch to the map view.

The map label for this gene is atoC [H]

Identifier: 94985999

GI number: 94985999

Start: 1997879

End: 1998298

Strand: Reverse

Name: atoC [H]

Synonym: Dgeo_1899

Alternate gene names: 94985999

Gene position: 1998298-1997879 (Counterclockwise)

Preceding gene: 94986002

Following gene: 94985998

Centisome position: 80.99

GC content: 64.05

Gene sequence:

>420_bases
GTGGAACGCCGACGGATCCTGCTGGTAGACGACAATCCGAACGACGTGGAACTGGCCCTGAACGCCTTTCAGGAAGACGG
TCTGGGTGAGTGTGATGTCATGGTCGCGAACAGCGGTCCCGAGGCGTTGGCCGTGTTGCGCGGCGCGGTTCCCCTGCCCG
ACGTCATTCTGCTTGACCTAAAGATGCCTCAGATGGACGGCCTAGCGGTCCTGGACGCTATCCGCAGCGAGGCCAGCACG
CGCGATATCCCGGTGGTCATGCTCAGCACGAGCGGTGAGACGCGCGACATTCGCGACAGCTACGCCCACGGCGCGAGCGC
CTACGTCATCAAGCCGTTGGACTTTACCCAGTTTCGCCAGGCGATCCAGACCATCACCGCCTTCTGGGCGCACCTGAACT
GCCGCCCGCGCCTGGGCTGA

Upstream 100 bases:

>100_bases
GCCCCAGATAGACATGTTTAACCACATCACACTTGGGTCACAGGACATGACCGAGAATTGGCGAAATTTTCATATTCAGT
CAGCTTGAAAGGGGCGAGCT

Downstream 100 bases:

>100_bases
GGCTCTTGAGACGGCGTTTACCCGCGCTGCCTTCCGTTTCGCGGCCCGCTAGGCTGACTGCATGCGCGTCTGGATCGGTT
GCGGCGGCTACACGAATGAC

Product: response regulator receiver protein

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MERRRILLVDDNPNDVELALNAFQEDGLGECDVMVANSGPEALAVLRGAVPLPDVILLDLKMPQMDGLAVLDAIRSEAST
RDIPVVMLSTSGETRDIRDSYAHGASAYVIKPLDFTQFRQAIQTITAFWAHLNCRPRLG

Sequences:

>Translated_139_residues
MERRRILLVDDNPNDVELALNAFQEDGLGECDVMVANSGPEALAVLRGAVPLPDVILLDLKMPQMDGLAVLDAIRSEAST
RDIPVVMLSTSGETRDIRDSYAHGASAYVIKPLDFTQFRQAIQTITAFWAHLNCRPRLG
>Mature_139_residues
MERRRILLVDDNPNDVELALNAFQEDGLGECDVMVANSGPEALAVLRGAVPLPDVILLDLKMPQMDGLAVLDAIRSEAST
RDIPVVMLSTSGETRDIRDSYAHGASAYVIKPLDFTQFRQAIQTITAFWAHLNCRPRLG

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=34.453781512605, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=31.9672131147541, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 15277; Mature: 15277

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRRILLVDDNPNDVELALNAFQEDGLGECDVMVANSGPEALAVLRGAVPLPDVILLDL
CCCCEEEEEECCCCCEEEEEEHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEE
KMPQMDGLAVLDAIRSEASTRDIPVVMLSTSGETRDIRDSYAHGASAYVIKPLDFTQFRQ
CCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHCCCCCEEEEECCCHHHHHH
AIQTITAFWAHLNCRPRLG
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MERRRILLVDDNPNDVELALNAFQEDGLGECDVMVANSGPEALAVLRGAVPLPDVILLDL
CCCCEEEEEECCCCCEEEEEEHHHCCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEEE
KMPQMDGLAVLDAIRSEASTRDIPVVMLSTSGETRDIRDSYAHGASAYVIKPLDFTQFRQ
CCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHCCCCCEEEEECCCHHHHHH
AIQTITAFWAHLNCRPRLG
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]