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The map label for this gene is rpiA [H]

Identifier: 94985366

GI number: 94985366

Start: 1344196

End: 1344882

Strand: Reverse

Name: rpiA [H]

Synonym: Dgeo_1265

Alternate gene names: 94985366

Gene position: 1344882-1344196 (Counterclockwise)

Preceding gene: 94985369

Following gene: 94985365

Centisome position: 54.51

GC content: 67.25

Gene sequence:

>687_bases
ATGCCTGACCTGGAAGCGCTGAAAAAGGAAGCCGCGCTGCGGGCCGTCACGCTGGTCAGAAGCGGCATGCGCGTGGGCCT
GGGAACGGGCAGCACCGCCAAGTACGCCATCCTGGCGATCGGAGAGCGGCTCGCGTCCGGCGACCTGCGGGGGGTGGTGG
GTGTGGCGACGAGTGATGCCTCGGAGGTGCTGGCCCGTCAGGTCGGCATCCCGGTCGAGCCACTTGACCCTCGTCCCCTC
GACCTCGCCATCGACGGTGCAGATGAGATCGACCCGGCGCTGAATCTCATCAAGGGCCTGGGCGGGGCGTTGCTGCGCGA
AAAGCTGACCGAGGTGCAGGCGCGGCAGCTGGTGATCATCGCCGACCACACCAAGCTGGTCACGCGCTTGGGTGAGCAAG
CGCCCCTGCCGGTCGAGATCGCCCGTTTCGGCTTTCTGTCCACCATCGAGCGGTTGCGCGCCCTGGTGCCCGGCGGACGG
CTGCGGCAACCCGGTGCGCAGCCCTTTGTGACCGACAACGGCAACTATATCTACGACGCCCAGCTGCCACAGAGCTTTGA
CCCCGTTGCCCTGGAACGGCAGCTGAAAGGCACGCTGGGTGTGGTGGAGACCGGCTTTTTCCTGGGTATGGCCGACCTCG
CCTTTGTGGCGGCACCGGAGGGAGTACGCGAGTTGCGCCGCCCCTGA

Upstream 100 bases:

>100_bases
CTGGTGAAAGCCTGGCGGAACGTCTCGGTGGATGGGCACGCCGACGCGGTGGCCGCCGCCATTGAGGCTGACCGGAAGAC
GCGCGGCGAGGCCTGAGCGC

Downstream 100 bases:

>100_bases
TGCGGAAGCGTGGAGGCAGGCCGTCACCGTGGACCGGTGCGATGCTCTTGGCGGCTTTGCTGGCTGCCTTTGGGATCAAC
TCCCCCTCTGCGCTGCGCCT

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPDLEALKKEAALRAVTLVRSGMRVGLGTGSTAKYAILAIGERLASGDLRGVVGVATSDASEVLARQVGIPVEPLDPRPL
DLAIDGADEIDPALNLIKGLGGALLREKLTEVQARQLVIIADHTKLVTRLGEQAPLPVEIARFGFLSTIERLRALVPGGR
LRQPGAQPFVTDNGNYIYDAQLPQSFDPVALERQLKGTLGVVETGFFLGMADLAFVAAPEGVRELRRP

Sequences:

>Translated_228_residues
MPDLEALKKEAALRAVTLVRSGMRVGLGTGSTAKYAILAIGERLASGDLRGVVGVATSDASEVLARQVGIPVEPLDPRPL
DLAIDGADEIDPALNLIKGLGGALLREKLTEVQARQLVIIADHTKLVTRLGEQAPLPVEIARFGFLSTIERLRALVPGGR
LRQPGAQPFVTDNGNYIYDAQLPQSFDPVALERQLKGTLGVVETGFFLGMADLAFVAAPEGVRELRRP
>Mature_227_residues
PDLEALKKEAALRAVTLVRSGMRVGLGTGSTAKYAILAIGERLASGDLRGVVGVATSDASEVLARQVGIPVEPLDPRPLD
LAIDGADEIDPALNLIKGLGGALLREKLTEVQARQLVIIADHTKLVTRLGEQAPLPVEIARFGFLSTIERLRALVPGGRL
RQPGAQPFVTDNGNYIYDAQLPQSFDPVALERQLKGTLGVVETGFFLGMADLAFVAAPEGVRELRRP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=234, Percent_Identity=35.8974358974359, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1789280, Length=225, Percent_Identity=38.2222222222222, Blast_Score=117, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17551758, Length=236, Percent_Identity=38.135593220339, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324669, Length=238, Percent_Identity=33.6134453781513, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281364072, Length=206, Percent_Identity=35.9223300970874, Blast_Score=120, Evalue=9e-28,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24291; Mature: 24159

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLEALKKEAALRAVTLVRSGMRVGLGTGSTAKYAILAIGERLASGDLRGVVGVATSDA
CCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
SEVLARQVGIPVEPLDPRPLDLAIDGADEIDPALNLIKGLGGALLREKLTEVQARQLVII
HHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCEEEEE
ADHTKLVTRLGEQAPLPVEIARFGFLSTIERLRALVPGGRLRQPGAQPFVTDNGNYIYDA
ECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEC
QLPQSFDPVALERQLKGTLGVVETGFFLGMADLAFVAAPEGVRELRRP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
PDLEALKKEAALRAVTLVRSGMRVGLGTGSTAKYAILAIGERLASGDLRGVVGVATSDA
CCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
SEVLARQVGIPVEPLDPRPLDLAIDGADEIDPALNLIKGLGGALLREKLTEVQARQLVII
HHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCEEEEE
ADHTKLVTRLGEQAPLPVEIARFGFLSTIERLRALVPGGRLRQPGAQPFVTDNGNYIYDA
ECCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEC
QLPQSFDPVALERQLKGTLGVVETGFFLGMADLAFVAAPEGVRELRRP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]