| Definition | Deinococcus geothermalis DSM 11300, complete genome. |
|---|---|
| Accession | NC_008025 |
| Length | 2,467,205 |
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The map label for this gene is bdhA [H]
Identifier: 94985058
GI number: 94985058
Start: 1018784
End: 1019560
Strand: Reverse
Name: bdhA [H]
Synonym: Dgeo_0952
Alternate gene names: 94985058
Gene position: 1019560-1018784 (Counterclockwise)
Preceding gene: 94985059
Following gene: 94985049
Centisome position: 41.32
GC content: 69.76
Gene sequence:
>777_bases ATGCCTTCCCAGGAACATCAGGAAGCCCGCGTCGCCCTCGTCACGGGCGGGAGCAGCGGCATCGGCCTCGCCATCGCGCA GCGGCTGCAGGCCGACGGGTTGAAGGTGGCCGTGCTGGACCTCGACCGCCCGCAGGCACGCGAGGGGGCAGAGCAGAATG GCTTCACCTTTATCGGCGCCGACCTTTCCCGCCGCGAGGACTGCCGCCGCGCAGTGGAGGAAACGGTGGCCGCGCTGGGA GGCTTGGACGTGCTGGTCAACAACGCGGGCTTTCAGCACATCGACCCCATCGCGGACTTTCCCGAAGACACCTGGGACAG CATGCTGCGCGTGATGCTGACCGCGCCGTTTTTGCTCACCAAGTACGCCTGGGGGTACCTCACGCGCTCGGGGCAGGGCC GCGTTGTGAATATCGCCTCCATCCACGGGCAGGTTGCCAGCCCCTTCAAGAGTGCCTATATCAGCGCCAAGCACGGGCTG ATCGGCCTGACGCGCACGGCGGCGCTGGAGGCGGGCGAGCAGGGCTTCACCGTGAACGCGATCTGCCCGGGCTACGTCCG CACGCCCCTGGTGGAGGGCCAGATCGCGGACCAGGCCCGCACCCGCGGCCTCAGCGAGCAGGAGGTCGAGCAGCGGGTGA TGCTCGAACCCGCCGCCATCAAGCGGCTGCTGGCGCCGGAGGACGTGGCGGCCCTCGCGAGCTACGTGGTCAGCCCGGCC GCCTGGGGCATGACGGGCGCGGTGCTGGACCTCGACCTGGGGTGGACGGCGCGCTAA
Upstream 100 bases:
>100_bases CCGCCAGGTCATCGCGCGGGAGGTGCGGGCGGCGGTCCTCTGATCGGCGCTGCCGGGCGTGTGAAACGCTCCCGTGACAC CTCCGCCGTAGACTCCCTCT
Downstream 100 bases:
>100_bases GGCGGGAGGGCCTATTTCGGCAGCCCGCCCACCGTCGTCAACGTCACGTCCTGGCAGCGGGCCAGGTGTAGAAAGCCGCG CAGCACATCCAGCATCTCCG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]
Number of amino acids: Translated: 258; Mature: 257
Protein sequence:
>258_residues MPSQEHQEARVALVTGGSSGIGLAIAQRLQADGLKVAVLDLDRPQAREGAEQNGFTFIGADLSRREDCRRAVEETVAALG GLDVLVNNAGFQHIDPIADFPEDTWDSMLRVMLTAPFLLTKYAWGYLTRSGQGRVVNIASIHGQVASPFKSAYISAKHGL IGLTRTAALEAGEQGFTVNAICPGYVRTPLVEGQIADQARTRGLSEQEVEQRVMLEPAAIKRLLAPEDVAALASYVVSPA AWGMTGAVLDLDLGWTAR
Sequences:
>Translated_258_residues MPSQEHQEARVALVTGGSSGIGLAIAQRLQADGLKVAVLDLDRPQAREGAEQNGFTFIGADLSRREDCRRAVEETVAALG GLDVLVNNAGFQHIDPIADFPEDTWDSMLRVMLTAPFLLTKYAWGYLTRSGQGRVVNIASIHGQVASPFKSAYISAKHGL IGLTRTAALEAGEQGFTVNAICPGYVRTPLVEGQIADQARTRGLSEQEVEQRVMLEPAAIKRLLAPEDVAALASYVVSPA AWGMTGAVLDLDLGWTAR >Mature_257_residues PSQEHQEARVALVTGGSSGIGLAIAQRLQADGLKVAVLDLDRPQAREGAEQNGFTFIGADLSRREDCRRAVEETVAALGG LDVLVNNAGFQHIDPIADFPEDTWDSMLRVMLTAPFLLTKYAWGYLTRSGQGRVVNIASIHGQVASPFKSAYISAKHGLI GLTRTAALEAGEQGFTVNAICPGYVRTPLVEGQIADQARTRGLSEQEVEQRVMLEPAAIKRLLAPEDVAALASYVVSPAA WGMTGAVLDLDLGWTAR
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=273, Percent_Identity=32.2344322344322, Blast_Score=118, Evalue=6e-27, Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=34.156378600823, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=32.6633165829146, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=30.0813008130081, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=27.7992277992278, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI59889578, Length=215, Percent_Identity=31.1627906976744, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=33.5106382978723, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=26.1061946902655, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI126723191, Length=204, Percent_Identity=31.8627450980392, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI40254992, Length=208, Percent_Identity=28.3653846153846, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.635838150289, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI142976729, Length=217, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI4504505, Length=269, Percent_Identity=26.7657992565056, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI20149619, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI109715829, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=5e-13, Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=29.8039215686275, Blast_Score=109, Evalue=1e-25, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.1497975708502, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=31.640625, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=31.7647058823529, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=29.6442687747036, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=29.6153846153846, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=30.5882352941176, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=29.4820717131474, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786701, Length=212, Percent_Identity=27.3584905660377, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.9595141700405, Blast_Score=72, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17561402, Length=269, Percent_Identity=29.7397769516729, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=29.9212598425197, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=28.4, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560676, Length=268, Percent_Identity=29.1044776119403, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=29.2307692307692, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=29.8892988929889, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=28.6274509803922, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562910, Length=240, Percent_Identity=27.9166666666667, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=26.2886597938144, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=26.2886597938144, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17538182, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=33, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17558006, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538486, Length=219, Percent_Identity=27.8538812785388, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17568967, Length=263, Percent_Identity=25.8555133079848, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538480, Length=218, Percent_Identity=28.4403669724771, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17563726, Length=239, Percent_Identity=25.5230125523013, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17551412, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=30.1020408163265, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17508895, Length=247, Percent_Identity=22.6720647773279, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17562904, Length=207, Percent_Identity=28.0193236714976, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562990, Length=190, Percent_Identity=27.8947368421053, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI72000259, Length=246, Percent_Identity=26.0162601626016, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17560150, Length=193, Percent_Identity=26.9430051813472, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=267, Percent_Identity=25.0936329588015, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=25.78125, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=30.5882352941176, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=31.3492063492063, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=31.2252964426877, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=30.7392996108949, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=28.0487804878049, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI21357041, Length=267, Percent_Identity=29.2134831460674, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=25.9911894273128, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=29.8449612403101, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI17737361, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24641232, Length=231, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI21357673, Length=190, Percent_Identity=27.8947368421053, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24649181, Length=221, Percent_Identity=25.7918552036199, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=27.6, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011294 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.30 [H]
Molecular weight: Translated: 27610; Mature: 27478
Theoretical pI: Translated: 4.96; Mature: 4.96
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPSQEHQEARVALVTGGSSGIGLAIAQRLQADGLKVAVLDLDRPQAREGAEQNGFTFIGA CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHCCCCCCCCEEEEC DLSRREDCRRAVEETVAALGGLDVLVNNAGFQHIDPIADFPEDTWDSMLRVMLTAPFLLT CHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH KYAWGYLTRSGQGRVVNIASIHGQVASPFKSAYISAKHGLIGLTRTAALEAGEQGFTVNA HHHHHHEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCEEEE ICPGYVRTPLVEGQIADQARTRGLSEQEVEQRVMLEPAAIKRLLAPEDVAALASYVVSPA ECCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCHH AWGMTGAVLDLDLGWTAR HCCCCCEEEEECCCCCCC >Mature Secondary Structure PSQEHQEARVALVTGGSSGIGLAIAQRLQADGLKVAVLDLDRPQAREGAEQNGFTFIGA CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHCCCCCCCCEEEEC DLSRREDCRRAVEETVAALGGLDVLVNNAGFQHIDPIADFPEDTWDSMLRVMLTAPFLLT CHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH KYAWGYLTRSGQGRVVNIASIHGQVASPFKSAYISAKHGLIGLTRTAALEAGEQGFTVNA HHHHHHEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCCEEEE ICPGYVRTPLVEGQIADQARTRGLSEQEVEQRVMLEPAAIKRLLAPEDVAALASYVVSPA ECCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCHH AWGMTGAVLDLDLGWTAR HCCCCCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9922248; 11481431 [H]