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The map label for this gene is lacF [H]

Identifier: 94984857

GI number: 94984857

Start: 812349

End: 813449

Strand: Reverse

Name: lacF [H]

Synonym: Dgeo_0750

Alternate gene names: 94984857

Gene position: 813449-812349 (Counterclockwise)

Preceding gene: 94984858

Following gene: 94984856

Centisome position: 32.97

GC content: 63.94

Gene sequence:

>1101_bases
ATGTTCAAGAGAGGCTTCACGGTCACGGCGTACCTGTTTCTGGCGCCGTTCTTGATCGCCGTGGCGATTTTCTTCTTCTA
CGCCTTCGGGCGCGCGCTGTACTACTCATTCACCAACTTCGACCTGTTCCACCCGCCGCAACTGATCGGCCTCAAACCCT
ACCGCGACGTGCTGGCAGATCCCTTTTTCCAGCGGGCGCTGGCCAACAGCCTGGTCTTCGCACTGGTGACCACCACGCTC
CAAACGGTCTTTGCGCTGCTGATGGCGGTCGCGCTCAACCACCGGCTGCGCGGCATGGCCTTTTTTCGCTCGGCGTGGTA
CATGCCCTCCATCACGAGCAGCGTGGTGATCACCCTGATCTTCCTGTGGCTGTTCCAGCGTCGGGGCGTGGCGAACTACC
TGATCACCCAGGGGCAGGCGTACCAGCCGCTGATCCTGACATTCCTGGGCGTGTTCGCCGCCGCGCAGATGGTGCAGGTG
CTGTGGGAACGCGCCCGCCGCCTGCCGGCTGGATGGTTCGACCCCGCCCTGGCCGCCATCAGCGCGCTGGTCGCCCTGCT
CCTGACCTGGGCGCTGAACTTCACCGGCGTGATCGGCGTGCGCGAGGTACCGCCCTTCGACTACCAGTACTTCGCGGACA
GGTGGATCACGCTGGGCGGCGTGAAGGTGCTGAGCATCCCGCTCCTCGTCGTGATCATCCAGAACACCTTCACGACCGTG
CCCACGCTGATGCTGTTCTTCCTGGCGGGCCTCCAGAACATTCCCCGCGCCCTGTATGAGGCAGCGGACATCGACGGCGC
CACGCCGCTGCAAAAGCTGCTGCGGGTAACGGTGCCCATGCTGCGTCCGGTCACCTTCTATGTGGTGACGGTCGGACTGA
TCGGCACCATGCAGATGTTCGACCAGGTCGCCGTGATCGGCAGCGCCGCGCCGCGTGAGACCCTCGTCACGCTCGCGTAC
TACGTGTACACCAATACGTTCCAGGCGGGAGCGGCCCCGGTCAACATGGCCTGCGCCGCCGCGATCATCCTCGCGTTGAT
CATCTTGGCGATGGTCTTTCTCCAGCGCCGCTTTTTCGTGGCTCCGGAGGCGAACTCATGA

Upstream 100 bases:

>100_bases
GCAGGACATGGCCACCTTCCAGAACCGCTGATCCTCACTCCCCTAGGGGCGAAGGTCTGCGGGCCTCTTCGCCCCTTTGC
ACGGCTTTCTGGGGGCAAGC

Downstream 100 bases:

>100_bases
CCGCCCTTCCGGGTCAGCCCACTCCGCAGCGGCGGAGCCTGCAAGACCAGGACCGCTGGCTGGCGCGCCGCCGCTGGGCA
CGCGCTGGGTGGCTCTACGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MFKRGFTVTAYLFLAPFLIAVAIFFFYAFGRALYYSFTNFDLFHPPQLIGLKPYRDVLADPFFQRALANSLVFALVTTTL
QTVFALLMAVALNHRLRGMAFFRSAWYMPSITSSVVITLIFLWLFQRRGVANYLITQGQAYQPLILTFLGVFAAAQMVQV
LWERARRLPAGWFDPALAAISALVALLLTWALNFTGVIGVREVPPFDYQYFADRWITLGGVKVLSIPLLVVIIQNTFTTV
PTLMLFFLAGLQNIPRALYEAADIDGATPLQKLLRVTVPMLRPVTFYVVTVGLIGTMQMFDQVAVIGSAAPRETLVTLAY
YVYTNTFQAGAAPVNMACAAAIILALIILAMVFLQRRFFVAPEANS

Sequences:

>Translated_366_residues
MFKRGFTVTAYLFLAPFLIAVAIFFFYAFGRALYYSFTNFDLFHPPQLIGLKPYRDVLADPFFQRALANSLVFALVTTTL
QTVFALLMAVALNHRLRGMAFFRSAWYMPSITSSVVITLIFLWLFQRRGVANYLITQGQAYQPLILTFLGVFAAAQMVQV
LWERARRLPAGWFDPALAAISALVALLLTWALNFTGVIGVREVPPFDYQYFADRWITLGGVKVLSIPLLVVIIQNTFTTV
PTLMLFFLAGLQNIPRALYEAADIDGATPLQKLLRVTVPMLRPVTFYVVTVGLIGTMQMFDQVAVIGSAAPRETLVTLAY
YVYTNTFQAGAAPVNMACAAAIILALIILAMVFLQRRFFVAPEANS
>Mature_366_residues
MFKRGFTVTAYLFLAPFLIAVAIFFFYAFGRALYYSFTNFDLFHPPQLIGLKPYRDVLADPFFQRALANSLVFALVTTTL
QTVFALLMAVALNHRLRGMAFFRSAWYMPSITSSVVITLIFLWLFQRRGVANYLITQGQAYQPLILTFLGVFAAAQMVQV
LWERARRLPAGWFDPALAAISALVALLLTWALNFTGVIGVREVPPFDYQYFADRWITLGGVKVLSIPLLVVIIQNTFTTV
PTLMLFFLAGLQNIPRALYEAADIDGATPLQKLLRVTVPMLRPVTFYVVTVGLIGTMQMFDQVAVIGSAAPRETLVTLAY
YVYTNTFQAGAAPVNMACAAAIILALIILAMVFLQRRFFVAPEANS

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789861, Length=136, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40828; Mature: 40828

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRGFTVTAYLFLAPFLIAVAIFFFYAFGRALYYSFTNFDLFHPPQLIGLKPYRDVLAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHCC
PFFQRALANSLVFALVTTTLQTVFALLMAVALNHRLRGMAFFRSAWYMPSITSSVVITLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FLWLFQRRGVANYLITQGQAYQPLILTFLGVFAAAQMVQVLWERARRLPAGWFDPALAAI
HHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SALVALLLTWALNFTGVIGVREVPPFDYQYFADRWITLGGVKVLSIPLLVVIIQNTFTTV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
PTLMLFFLAGLQNIPRALYEAADIDGATPLQKLLRVTVPMLRPVTFYVVTVGLIGTMQMF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQVAVIGSAAPRETLVTLAYYVYTNTFQAGAAPVNMACAAAIILALIILAMVFLQRRFFV
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
APEANS
CCCCCC
>Mature Secondary Structure
MFKRGFTVTAYLFLAPFLIAVAIFFFYAFGRALYYSFTNFDLFHPPQLIGLKPYRDVLAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHCC
PFFQRALANSLVFALVTTTLQTVFALLMAVALNHRLRGMAFFRSAWYMPSITSSVVITLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FLWLFQRRGVANYLITQGQAYQPLILTFLGVFAAAQMVQVLWERARRLPAGWFDPALAAI
HHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SALVALLLTWALNFTGVIGVREVPPFDYQYFADRWITLGGVKVLSIPLLVVIIQNTFTTV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
PTLMLFFLAGLQNIPRALYEAADIDGATPLQKLLRVTVPMLRPVTFYVVTVGLIGTMQMF
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQVAVIGSAAPRETLVTLAYYVYTNTFQAGAAPVNMACAAAIILALIILAMVFLQRRFFV
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
APEANS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]