Click here to switch to the map view.

The map label for this gene is trpE [H]

Identifier: 94984605

GI number: 94984605

Start: 517141

End: 519069

Strand: Reverse

Name: trpE [H]

Synonym: Dgeo_0498

Alternate gene names: 94984605

Gene position: 519069-517141 (Counterclockwise)

Preceding gene: 94984609

Following gene: 94984604

Centisome position: 21.04

GC content: 70.71

Gene sequence:

>1929_bases
GTGACGGCTCGCTCTACCGCAACCCTGCCTGCTCACCTGGGCGCGCTTTCCCCCGCCGACGTGCTGCTGCGGCTGCGAGC
AGCGGGGGCGCCCGGCACCGTGCTGCTTGAATCTCTGGGACCGGTGGTGGACCATGGCCGCTTCAGCTTCCTGAGCGCGT
GGCCGGTGCGGATGCAAGCCACAGTTCCGGAGAGACCAGCAGGTGAGGCGTTCTTTCCCGCCTGGCTCGGCGGCCTCCAG
TACGAAGCGGCGCGCGCCTTTGGGCTTGACACCCATGTCTCCGCGGCGCGCACCGCCTGGTGGGGCCTTTATCCCAGCGG
CCTGGTTTGGGACCGGGAGGCCGGCACGCTGGACATCGTGGGCGAAGCCGCGCACGTGGACTGGCAGGCGCTGCTGGCAC
GCACCCCAGCCCCCCTCCCCGCCCTCCAGGTGGGCGAATTCGGTGCGGACGACGTGGACTACCCGGCGGGCGTACGGGCC
GTGCAGGAACTGATTCGGGCAGGAGAGGTCTATCAAGTCAACCTCTCGCGCGGCGTACGAGCAACGGCAACCGGCGATCC
GCTGGCCGCTTACCTGCGGCTGCGCGAGGTGAACCCCAGTCCCTTCATGGCCTTTCTCGACCTTGGGGAGGAGGTCGTGG
TGTCGTGCAGCCCCGAGCGGCTGGTTCTCTGGGAGGGAAGCAGCGTCTCGGCCCGGCCCATCGCCGGCACGCGGCGGCGC
GGAGACACCCCGGAGGAGGACGCCGCCCTCGAAGCTGAACTGCGCCGCGATCCCAAAGAGATCAGCGAGCACACCATGCT
GGTGGACCTGGCACGCCATGACCTAGGCCGCGTCGCGGCGGCGGGCAGCGTCCACGTTCCCGACCTGGGGCTGGTCGAAC
GCTATAGCCACGTGATGCACCTGGTCTCGGAGGTGAGGGCCACCGCCCGGCCTGGTCTGACGGTGCACGACCTGCTCGCC
GCCACCTTTCCCGGCGGCACCATCACGGGCGCACCCAAAGCCCGCGTGATGACCGCCATTCGCGAGCTCGAACCGGGACC
GCGCGGCTGGTACACGGGTGGCGTGGGGATCGTGAGCGGCGCGCGGGTGGACGTGAATATCCTGATCCGAACGGCGGCCT
TCCGCCGCTGTGGGGCGGGCTGGATCGCCGAGGTCCGCGCCGGGGGCGGCACCGTCATCGATGCCGATCCGGCCCGCGAG
GCGCAGGAGACGGTTCATAAGGCGCAGGCGCTGCTGGCGGTGCTGTCGGGGAAACCAGGCCGACCAGCGCAGGCTCCGGC
ACCCCCGATTCCCGGTCACGCCTGGGCACCACCCCCCGCCTCCTCCCAGACAGGCCTGCGCGTGCTGCTGCTGGACAACC
GGGATTCCTTTACCCTCAACCTCGTCCATGACCTGCTGGCGCTCGGCGCAGCGGTAGACCTGCGGTCACAGGATGAGGAC
GTCGCGGCGCTGCTTGCCGCCGAGCCGGATGCCGTGCTGATCGGGCCGGGACCGGGAACGCCAGGCACGAGCGGCTGTAC
CTTGGCCCTCACGCAGGCCTGCTTGGACCAAGGGATGCCGCTCCTGGGCGTGTGTCTGGGCCACCAGGCGCTGGGCGCGG
TGCTGGGCGGACGGGTGGAACGGGCTGCACCCGTTCATGGGCGCCCAGAGGCCGTCCGGCACGCGGGCGAGGGCCTCTTT
GCCGGGATCGCGGACGGTACGCCGTTTGGACGTTACCACTCCCTGGTCGTGCGCGGCCTCCCCGAGGAACTGGTGACCGC
CCGCAGCGAGGACGGCGAAGTGATGGCCCTGCAGGTGCCGGGACGGCCCGCCTGGGGCGTGCAGTTCCATCCCGAGAGCG
TGCTGAGTCCGGCTGGGCGAAGATTGCTGGGAAACTGGCTGCGGCTCTCTGCCCTCCACACCGCCCCCCAGCGCCAGGTC
AGGCCATGA

Upstream 100 bases:

>100_bases
ACTCTTCAAACCCGGACAGAAAGTAAGGATTTGGATGGAAGACAAATGAAGGAGCCACAGGACGCCACCGGTACTGCGCC
GCTCCCCTAGAATCCAGCGC

Downstream 100 bases:

>100_bases
GGCCGCTTCCCACCGAGGTCGACACGGGGGCCTGGCTCCACGGCGCCACGGCCTTTACGACCCTCCGCACGCACTGGGGG
AAGCCGCTGCTGTGGGAAGC

Product: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MTARSTATLPAHLGALSPADVLLRLRAAGAPGTVLLESLGPVVDHGRFSFLSAWPVRMQATVPERPAGEAFFPAWLGGLQ
YEAARAFGLDTHVSAARTAWWGLYPSGLVWDREAGTLDIVGEAAHVDWQALLARTPAPLPALQVGEFGADDVDYPAGVRA
VQELIRAGEVYQVNLSRGVRATATGDPLAAYLRLREVNPSPFMAFLDLGEEVVVSCSPERLVLWEGSSVSARPIAGTRRR
GDTPEEDAALEAELRRDPKEISEHTMLVDLARHDLGRVAAAGSVHVPDLGLVERYSHVMHLVSEVRATARPGLTVHDLLA
ATFPGGTITGAPKARVMTAIRELEPGPRGWYTGGVGIVSGARVDVNILIRTAAFRRCGAGWIAEVRAGGGTVIDADPARE
AQETVHKAQALLAVLSGKPGRPAQAPAPPIPGHAWAPPPASSQTGLRVLLLDNRDSFTLNLVHDLLALGAAVDLRSQDED
VAALLAAEPDAVLIGPGPGTPGTSGCTLALTQACLDQGMPLLGVCLGHQALGAVLGGRVERAAPVHGRPEAVRHAGEGLF
AGIADGTPFGRYHSLVVRGLPEELVTARSEDGEVMALQVPGRPAWGVQFHPESVLSPAGRRLLGNWLRLSALHTAPQRQV
RP

Sequences:

>Translated_642_residues
MTARSTATLPAHLGALSPADVLLRLRAAGAPGTVLLESLGPVVDHGRFSFLSAWPVRMQATVPERPAGEAFFPAWLGGLQ
YEAARAFGLDTHVSAARTAWWGLYPSGLVWDREAGTLDIVGEAAHVDWQALLARTPAPLPALQVGEFGADDVDYPAGVRA
VQELIRAGEVYQVNLSRGVRATATGDPLAAYLRLREVNPSPFMAFLDLGEEVVVSCSPERLVLWEGSSVSARPIAGTRRR
GDTPEEDAALEAELRRDPKEISEHTMLVDLARHDLGRVAAAGSVHVPDLGLVERYSHVMHLVSEVRATARPGLTVHDLLA
ATFPGGTITGAPKARVMTAIRELEPGPRGWYTGGVGIVSGARVDVNILIRTAAFRRCGAGWIAEVRAGGGTVIDADPARE
AQETVHKAQALLAVLSGKPGRPAQAPAPPIPGHAWAPPPASSQTGLRVLLLDNRDSFTLNLVHDLLALGAAVDLRSQDED
VAALLAAEPDAVLIGPGPGTPGTSGCTLALTQACLDQGMPLLGVCLGHQALGAVLGGRVERAAPVHGRPEAVRHAGEGLF
AGIADGTPFGRYHSLVVRGLPEELVTARSEDGEVMALQVPGRPAWGVQFHPESVLSPAGRRLLGNWLRLSALHTAPQRQV
RP
>Mature_641_residues
TARSTATLPAHLGALSPADVLLRLRAAGAPGTVLLESLGPVVDHGRFSFLSAWPVRMQATVPERPAGEAFFPAWLGGLQY
EAARAFGLDTHVSAARTAWWGLYPSGLVWDREAGTLDIVGEAAHVDWQALLARTPAPLPALQVGEFGADDVDYPAGVRAV
QELIRAGEVYQVNLSRGVRATATGDPLAAYLRLREVNPSPFMAFLDLGEEVVVSCSPERLVLWEGSSVSARPIAGTRRRG
DTPEEDAALEAELRRDPKEISEHTMLVDLARHDLGRVAAAGSVHVPDLGLVERYSHVMHLVSEVRATARPGLTVHDLLAA
TFPGGTITGAPKARVMTAIRELEPGPRGWYTGGVGIVSGARVDVNILIRTAAFRRCGAGWIAEVRAGGGTVIDADPAREA
QETVHKAQALLAVLSGKPGRPAQAPAPPIPGHAWAPPPASSQTGLRVLLLDNRDSFTLNLVHDLLALGAAVDLRSQDEDV
AALLAAEPDAVLIGPGPGTPGTSGCTLALTQACLDQGMPLLGVCLGHQALGAVLGGRVERAAPVHGRPEAVRHAGEGLFA
GIADGTPFGRYHSLVVRGLPEELVTARSEDGEVMALQVPGRPAWGVQFHPESVLSPAGRRLLGNWLRLSALHTAPQRQVR
P

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=290, Percent_Identity=41.7241379310345, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI1787518, Length=288, Percent_Identity=42.0138888888889, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=44.1489361702128, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787517, Length=200, Percent_Identity=37, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320935, Length=276, Percent_Identity=38.0434782608696, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322638, Length=199, Percent_Identity=36.1809045226131, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324361, Length=295, Percent_Identity=26.1016949152542, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 67668; Mature: 67537

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARSTATLPAHLGALSPADVLLRLRAAGAPGTVLLESLGPVVDHGRFSFLSAWPVRMQA
CCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCEEEEEECCEEEEE
TVPERPAGEAFFPAWLGGLQYEAARAFGLDTHVSAARTAWWGLYPSGLVWDREAGTLDIV
CCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCEEEEE
GEAAHVDWQALLARTPAPLPALQVGEFGADDVDYPAGVRAVQELIRAGEVYQVNLSRGVR
CCCHHCCHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCEE
ATATGDPLAAYLRLREVNPSPFMAFLDLGEEVVVSCSPERLVLWEGSSVSARPIAGTRRR
EECCCCHHEEHHHHCCCCCCCHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCC
GDTPEEDAALEAELRRDPKEISEHTMLVDLARHDLGRVAAAGSVHVPDLGLVERYSHVMH
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LVSEVRATARPGLTVHDLLAATFPGGTITGAPKARVMTAIRELEPGPRGWYTGGVGIVSG
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEECC
ARVDVNILIRTAAFRRCGAGWIAEVRAGGGTVIDADPAREAQETVHKAQALLAVLSGKPG
CEEEEEEEEEHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
RPAQAPAPPIPGHAWAPPPASSQTGLRVLLLDNRDSFTLNLVHDLLALGAAVDLRSQDED
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHCCHHCCCCCCCC
VAALLAAEPDAVLIGPGPGTPGTSGCTLALTQACLDQGMPLLGVCLGHQALGAVLGGRVE
HHHHEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
RAAPVHGRPEAVRHAGEGLFAGIADGTPFGRYHSLVVRGLPEELVTARSEDGEVMALQVP
CCCCCCCCHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEECC
GRPAWGVQFHPESVLSPAGRRLLGNWLRLSALHTAPQRQVRP
CCCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
TARSTATLPAHLGALSPADVLLRLRAAGAPGTVLLESLGPVVDHGRFSFLSAWPVRMQA
CCCCCCCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHCCCCEEEEEECCEEEEE
TVPERPAGEAFFPAWLGGLQYEAARAFGLDTHVSAARTAWWGLYPSGLVWDREAGTLDIV
CCCCCCCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCEEEEE
GEAAHVDWQALLARTPAPLPALQVGEFGADDVDYPAGVRAVQELIRAGEVYQVNLSRGVR
CCCHHCCHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCEE
ATATGDPLAAYLRLREVNPSPFMAFLDLGEEVVVSCSPERLVLWEGSSVSARPIAGTRRR
EECCCCHHEEHHHHCCCCCCCHHHHHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCC
GDTPEEDAALEAELRRDPKEISEHTMLVDLARHDLGRVAAAGSVHVPDLGLVERYSHVMH
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LVSEVRATARPGLTVHDLLAATFPGGTITGAPKARVMTAIRELEPGPRGWYTGGVGIVSG
HHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEECC
ARVDVNILIRTAAFRRCGAGWIAEVRAGGGTVIDADPAREAQETVHKAQALLAVLSGKPG
CEEEEEEEEEHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
RPAQAPAPPIPGHAWAPPPASSQTGLRVLLLDNRDSFTLNLVHDLLALGAAVDLRSQDED
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHCCHHCCCCCCCC
VAALLAAEPDAVLIGPGPGTPGTSGCTLALTQACLDQGMPLLGVCLGHQALGAVLGGRVE
HHHHEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
RAAPVHGRPEAVRHAGEGLFAGIADGTPFGRYHSLVVRGLPEELVTARSEDGEVMALQVP
CCCCCCCCHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEECC
GRPAWGVQFHPESVLSPAGRRLLGNWLRLSALHTAPQRQVRP
CCCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]