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The map label for this gene is yngJ [H]

Identifier: 94984536

GI number: 94984536

Start: 438926

End: 440068

Strand: Reverse

Name: yngJ [H]

Synonym: Dgeo_0428

Alternate gene names: 94984536

Gene position: 440068-438926 (Counterclockwise)

Preceding gene: 94984537

Following gene: 94984535

Centisome position: 17.84

GC content: 65.35

Gene sequence:

>1143_bases
ATGGACTTCACGCTGCCCGAGGACCTGCGCGATATGCAGGCGACCGTCCGTGACTTCATGCTCAACGTGGTGGAGGCGCG
CGCGCACGAGATCGAGGAAACGAACCGCGTGCCCCCCGAACTGCTGCGTCAAGCCGCCGAGCTGGGTCTTTTCGGCCTGA
GCATTCCCGAGGAGTACGGCGGCGTCAGACTGGGGATGCTGGGCCGCTGCGCGGTGTACGAGGCGATGGGCGAGGGACAC
ATGGGTTTTGGCGGCGTCATCAGCGCGCATGCCTCGATCGGCACCAGCGGGCTGGTGAAGCTGGGCACAGAGGAGCAAAA
ACGGCGCTTCCTGCCGCGCATGGCAAGCGGCGAGTGCATCGCGGGCTTTGCCATCACCGAGCCGTCGAGCGGGTCGGACG
CGGCCAACATCCGGACCAAGGCCGAGAAACGCGGCGACGTGTACGTGTTAAACGGCACCAAGCACTACATCTCCAATGCG
CCGATTGCCGGGCTGCTCACCGTCATCGCGATCACCGATCCCTCACAGGGCACGCGCGGGATGAGTGCCTTTCTGGTCGA
GCCGCAGAGCACGCCCGGCGTCTCGATCGGCAAGATCGACGAGAAGATGGGCCAGAAGGGGGCGCTCTCCTCTGAGGTGA
TTTTTCAGGACGCGGAGATCCCGGCAGCGAACCTGCTCGGCCCCGAGAACCTCGGCTACCGCGAGGCGCTCGGTATCCTG
ACCAACGGGCGGGTGGGGATTGCCGCGCGCTCGACCGGCGCAATGCAGCGGCTGCTTGACCTCTCGGTCGCACATGCCAA
GACCCGCGAACAGTTCGGGCAGCCCATCGCCCAGTTTCAGGCCGTGCAGTTCATGCTGGCCGAGATGGAGGTTGCCATCC
AGACCAGTCGGCTGCTGTGGCAGAAGGTCGCCTGGATGGTGGACCAAGGCCAGGACGTGCGCCGGATGGCCTCGGTGGCG
AAGTACCACGCGACCGAAATGCTCTCGCAGGTGGCCGACAAGGCCGTGCAGGTTGCAGGCGGCATGGGCTACATGAAGGA
TTCTCCCGTCGAGCGCTTCTACCGCGACCAACGCCTGCTGCGCATCTACGAGGGCACCAGCGAGATTCAGAAGCTGATCA
TCGCCCGGAGCCTGCTGGCGTAG

Upstream 100 bases:

>100_bases
GGAGAGGCCAAGCGAGGTGTCAATGAGGGGAAGACAGCGGCTGGCCCTGCCCCCACCCCACTGACACCTGCCCCCTTCTC
GGCGTAGCCTGTCCTCACCT

Downstream 100 bases:

>100_bases
CTGGTCCTTGGGAGCGGGCGGCACGTCGCGCTGGAACCGTGGCGACCGGAAGGTGCTTCTTCCACGACAAGCGTCACCGC
CGGCAGCACTCAACATTTCG

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDFTLPEDLRDMQATVRDFMLNVVEARAHEIEETNRVPPELLRQAAELGLFGLSIPEEYGGVRLGMLGRCAVYEAMGEGH
MGFGGVISAHASIGTSGLVKLGTEEQKRRFLPRMASGECIAGFAITEPSSGSDAANIRTKAEKRGDVYVLNGTKHYISNA
PIAGLLTVIAITDPSQGTRGMSAFLVEPQSTPGVSIGKIDEKMGQKGALSSEVIFQDAEIPAANLLGPENLGYREALGIL
TNGRVGIAARSTGAMQRLLDLSVAHAKTREQFGQPIAQFQAVQFMLAEMEVAIQTSRLLWQKVAWMVDQGQDVRRMASVA
KYHATEMLSQVADKAVQVAGGMGYMKDSPVERFYRDQRLLRIYEGTSEIQKLIIARSLLA

Sequences:

>Translated_380_residues
MDFTLPEDLRDMQATVRDFMLNVVEARAHEIEETNRVPPELLRQAAELGLFGLSIPEEYGGVRLGMLGRCAVYEAMGEGH
MGFGGVISAHASIGTSGLVKLGTEEQKRRFLPRMASGECIAGFAITEPSSGSDAANIRTKAEKRGDVYVLNGTKHYISNA
PIAGLLTVIAITDPSQGTRGMSAFLVEPQSTPGVSIGKIDEKMGQKGALSSEVIFQDAEIPAANLLGPENLGYREALGIL
TNGRVGIAARSTGAMQRLLDLSVAHAKTREQFGQPIAQFQAVQFMLAEMEVAIQTSRLLWQKVAWMVDQGQDVRRMASVA
KYHATEMLSQVADKAVQVAGGMGYMKDSPVERFYRDQRLLRIYEGTSEIQKLIIARSLLA
>Mature_380_residues
MDFTLPEDLRDMQATVRDFMLNVVEARAHEIEETNRVPPELLRQAAELGLFGLSIPEEYGGVRLGMLGRCAVYEAMGEGH
MGFGGVISAHASIGTSGLVKLGTEEQKRRFLPRMASGECIAGFAITEPSSGSDAANIRTKAEKRGDVYVLNGTKHYISNA
PIAGLLTVIAITDPSQGTRGMSAFLVEPQSTPGVSIGKIDEKMGQKGALSSEVIFQDAEIPAANLLGPENLGYREALGIL
TNGRVGIAARSTGAMQRLLDLSVAHAKTREQFGQPIAQFQAVQFMLAEMEVAIQTSRLLWQKVAWMVDQGQDVRRMASVA
KYHATEMLSQVADKAVQVAGGMGYMKDSPVERFYRDQRLLRIYEGTSEIQKLIIARSLLA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=38.1333333333333, Blast_Score=271, Evalue=5e-73,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=36.6754617414248, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=36.6754617414248, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=36.5789473684211, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=38.2051282051282, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=38.2051282051282, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=33.6870026525199, Blast_Score=242, Evalue=5e-64,
Organism=Homo sapiens, GI21361497, Length=389, Percent_Identity=36.7609254498715, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=37.9008746355685, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=35.1063829787234, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=33.9473684210526, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI4503943, Length=342, Percent_Identity=29.5321637426901, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI7669494, Length=333, Percent_Identity=29.7297297297297, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=28.7878787878788, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=28.7878787878788, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI38505218, Length=283, Percent_Identity=30.0353356890459, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=27.8947368421053, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=30.46875, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI87081702, Length=379, Percent_Identity=26.3852242744063, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87082384, Length=271, Percent_Identity=29.520295202952, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=37.597911227154, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=37.0757180156658, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI71985184, Length=386, Percent_Identity=38.60103626943, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=35.3403141361257, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=34.1397849462366, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=34.2175066312997, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17506239, Length=362, Percent_Identity=33.9779005524862, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=32.9815303430079, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI71985192, Length=299, Percent_Identity=40.4682274247492, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI71990804, Length=308, Percent_Identity=33.1168831168831, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=27.3936170212766, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=25.2717391304348, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=368, Percent_Identity=25, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=29.0909090909091, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=30.9917355371901, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=30.3135888501742, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI86563383, Length=312, Percent_Identity=27.5641025641026, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=312, Percent_Identity=27.5641025641026, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17531913, Length=177, Percent_Identity=27.683615819209, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=38.1333333333333, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=36.6754617414248, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=42.0588235294118, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=37.6657824933687, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=32.8877005347594, Blast_Score=238, Evalue=4e-63,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=32.3684210526316, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI19920834, Length=358, Percent_Identity=29.8882681564246, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI221473076, Length=314, Percent_Identity=24.203821656051, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550141, Length=314, Percent_Identity=24.203821656051, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41291; Mature: 41291

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTLPEDLRDMQATVRDFMLNVVEARAHEIEETNRVPPELLRQAAELGLFGLSIPEEYG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCCCHHHC
GVRLGMLGRCAVYEAMGEGHMGFGGVISAHASIGTSGLVKLGTEEQKRRFLPRMASGECI
CEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHCCCCCCCCEE
AGFAITEPSSGSDAANIRTKAEKRGDVYVLNGTKHYISNAPIAGLLTVIAITDPSQGTRG
EEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCHHHHCCCCHHHEEEEEEEECCCCCCCC
MSAFLVEPQSTPGVSIGKIDEKMGQKGALSSEVIFQDAEIPAANLLGPENLGYREALGIL
CEEEEECCCCCCCCCCCHHHHHHCCCCCCCHHHEEECCCCCHHHCCCCCCCCHHHHHHHH
TNGRVGIAARSTGAMQRLLDLSVAHAKTREQFGQPIAQFQAVQFMLAEMEVAIQTSRLLW
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QKVAWMVDQGQDVRRMASVAKYHATEMLSQVADKAVQVAGGMGYMKDSPVERFYRDQRLL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RIYEGTSEIQKLIIARSLLA
HHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFTLPEDLRDMQATVRDFMLNVVEARAHEIEETNRVPPELLRQAAELGLFGLSIPEEYG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCCCHHHC
GVRLGMLGRCAVYEAMGEGHMGFGGVISAHASIGTSGLVKLGTEEQKRRFLPRMASGECI
CEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHHHCCCCCCCCEE
AGFAITEPSSGSDAANIRTKAEKRGDVYVLNGTKHYISNAPIAGLLTVIAITDPSQGTRG
EEEEEECCCCCCCCHHHHHHHHCCCCEEEECCCHHHHCCCCHHHEEEEEEEECCCCCCCC
MSAFLVEPQSTPGVSIGKIDEKMGQKGALSSEVIFQDAEIPAANLLGPENLGYREALGIL
CEEEEECCCCCCCCCCCHHHHHHCCCCCCCHHHEEECCCCCHHHCCCCCCCCHHHHHHHH
TNGRVGIAARSTGAMQRLLDLSVAHAKTREQFGQPIAQFQAVQFMLAEMEVAIQTSRLLW
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QKVAWMVDQGQDVRRMASVAKYHATEMLSQVADKAVQVAGGMGYMKDSPVERFYRDQRLL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RIYEGTSEIQKLIIARSLLA
HHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]