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The map label for this gene is quiP [H]

Identifier: 94984377

GI number: 94984377

Start: 261023

End: 263392

Strand: Reverse

Name: quiP [H]

Synonym: Dgeo_0269

Alternate gene names: 94984377

Gene position: 263392-261023 (Counterclockwise)

Preceding gene: 94984378

Following gene: 94984373

Centisome position: 10.68

GC content: 68.06

Gene sequence:

>2370_bases
ATGAGGAGACTCGTTCGGGTCGGACGTGGCGTGCTGTGGGTGTTGCTGCTGGTGCTGCTGCTTGCGCTGGGAGCAGTGGT
GTGGCTCAAGGAGACCTCCAGGCCGCAGGTGAGCGGGACGCTGACGCTGCCGGGGCTCGCGGGACCGGTCAGCGTCACAC
GCGACGCCTGGGGCGTGCCGCACATCCGCGCGCAGGCGTCGGACGAGGACGCGATGTTCGCGCTGGGCTTCGTCCACGCG
CAGGACCGGGCCTGGCAGATGGACTTCCAACGCCGCGTCGCGCAGGGGCGGCTGGCGGAGGTTCTCGGCGAGGCGGCACT
CCCGCAGGACCGGTTTTTGCGAACCTGGGGCTTTTACCGAGCGGCGCAGTCGGCGCTGCCGGCTCTCTCCGAACAGGCAC
GGCGAATGGTGCGGGCCTACACCGCAGGCGTCAACGCGGGCTTCGCGCAGGGCAGGCTTGCACCGGAATTCCGCATCCTG
GGCTATACGCCCGAACCCTGGACCGACGTGGATTCCATCGCCTGGAGCAAGCTGATGGCCTACGACCTGGGCGGCAATGC
CGACGACGAGATCCTGGGGACGCAGGTGGTGAGGCGTCTGGGTGAGGCCAAGCTGAATGAGGTGTTGCCCCCCTATCCGC
CACAGGCCCCCACCATCCTCAGCCGTGAAGAACTGGGGCTGCAGGCTCAGGCGCCGCACCACCGGAGGGTGGCGACCGTC
CTGCCCGCCGCCACCCTGCGCGCGCTCCAGGCCCAGCTGGAGGCGGCCCGCGCCCTGGGCCTGGAGCGTCTTCCTGGCAA
GGGAAGCAACGACTGGGTGATCGCGGGGAGCCGCACCGCCAGCGGCAAACCCATCCTGGCCGACGACCCGCACCTGGCCC
TCAGCAGCCCGATGCTGTGGTATCTGGCCGACGTGCAGGGGCCGCGGCTGCGGGCCATCGGCGCGACCATTCCCGGACTG
CCCGGCATCGTGATCGGGCGCAATGACCGCGTCGCCTGGGGCGTGACCAACGTCAATCCCGATGTGCAGGATCTCTATAT
TGAGCCGGACGGCGCGAAGCTGACTGCGCGCACCGAGGTCATCAAGGTCAAGGGCCAGCCGGACGTCCACCTCACGGTCC
GCGAGAGCGAACACGGCCCGATCATCAGCGACGTGGGCGCGGGGGCAGTGGGACCGCGGGTGGCGCTGAAGTGGACGGCG
CTGCAACCGGGCGATACCACGTTGGAGGCCTTCCTGGGCCTCAATTACGCGCGGAATTGGCCGGACTTTGTGGCGGCGCT
GAAGAGGTACGTGGCGCCCAGCCAGAACTTTGTCTATGCCGACGTGGACGGCAACATCGGCTATTACGCGCCCGGGCGGG
TACCCATTCGCCGGGGCTGGGACGGCTCGCTCCCGGTGCCAGGGGATGGCCAGCACGAGTGGAGCGGCTTTATCCCCTTC
GCGCAACTGCCACACACCTTCAATCCCGCCGACGGCCTGGTCGTCACCGCCAACAACAAGGTCGTCCCCGAGGGCTACCC
CTTCAACCTCGGCAACATCCGCAACTGGGCCGAGCCGTACCGCGCCGAGCGCATCACCGCGCTGCTGACGCAAAAGCCGC
GTGAGCTGACGGTGGACGACGTGAAACGGGTGCAGCTGGACACGGTGAGCCTGGTGTGGCGCGACCTGAAACCCTTCCTG
CTCGCCACGCGGCCCGACGGTGACCTCAGCCGGCAGGCACTGGAGCAGTTGCGGGGCTGGAACGGAGACGAGCGGATAGA
CGTCGTGCCGCCCACCATCTTCGAGGCGTGGCTCGCAGAGCTTCAGCAGATGGCGCAAGACGAGCTGGGGGACGGGACAC
GCCTGAGCAGCCTGGCCGTGCTGAATCAGCTGCGGGCCAACGGTCAACTGTGCCGCAACGAACGCGACGAGACCAGCAGA
CCGCAGGACTGCGCGGGCGAAATGCAGGCCAGCCTGAAACGCGCCGTAGACCGCCTGGCCGCCCGCCTCGGCCCCAATCC
TGCGGGCTGGACCTACGGCAAGGTGCACACCGTGGCCAGCAACCACCGTGCCTTTGGCGGCGTGAAGGCGCTGGGCTGGC
TCTTTAACCACAGTACGCCCACCAACGGCGGGACCAACACGGTCAATGTTGCCCGCCCCGACCCCGACACCCTGCGGCAG
ACCCAAGGGCCGAGCTACCGCCAGATCATCGACCTCTCGGACCTCAACCGCAGCATCTACGTAGGCACCCTGGGCCAGAG
CGGGAATCCTTTTGGGGATCATGTCAGCGACCAGCAGAGGCTCTGGGCAGCGGGCGAGTACCTCCCCATGAGCACAGACG
CGCAAGACTGGGGACGGACAACGACACTGACACTGACACCCCAGCGTTGA

Upstream 100 bases:

>100_bases
CGCCCAGCGGGGAAACCGCTCAGCCCCCTGAACGGGTACGCCCACAGCCCCGGCTCCTCACCGTATCCTGTACTCCGTCT
AAAAAGAAAAAGGAGGCGGG

Downstream 100 bases:

>100_bases
AGTGGACCGGAGCAGGCTCAGCCGTGCAAGGGACAGCGCCCCGCCTGCCGCTCCTCCCACGCCGGAGGCTGCGGCACGAA
GCGGGGCGACTCGTCGCCGT

Product: penicillin amidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 789; Mature: 789

Protein sequence:

>789_residues
MRRLVRVGRGVLWVLLLVLLLALGAVVWLKETSRPQVSGTLTLPGLAGPVSVTRDAWGVPHIRAQASDEDAMFALGFVHA
QDRAWQMDFQRRVAQGRLAEVLGEAALPQDRFLRTWGFYRAAQSALPALSEQARRMVRAYTAGVNAGFAQGRLAPEFRIL
GYTPEPWTDVDSIAWSKLMAYDLGGNADDEILGTQVVRRLGEAKLNEVLPPYPPQAPTILSREELGLQAQAPHHRRVATV
LPAATLRALQAQLEAARALGLERLPGKGSNDWVIAGSRTASGKPILADDPHLALSSPMLWYLADVQGPRLRAIGATIPGL
PGIVIGRNDRVAWGVTNVNPDVQDLYIEPDGAKLTARTEVIKVKGQPDVHLTVRESEHGPIISDVGAGAVGPRVALKWTA
LQPGDTTLEAFLGLNYARNWPDFVAALKRYVAPSQNFVYADVDGNIGYYAPGRVPIRRGWDGSLPVPGDGQHEWSGFIPF
AQLPHTFNPADGLVVTANNKVVPEGYPFNLGNIRNWAEPYRAERITALLTQKPRELTVDDVKRVQLDTVSLVWRDLKPFL
LATRPDGDLSRQALEQLRGWNGDERIDVVPPTIFEAWLAELQQMAQDELGDGTRLSSLAVLNQLRANGQLCRNERDETSR
PQDCAGEMQASLKRAVDRLAARLGPNPAGWTYGKVHTVASNHRAFGGVKALGWLFNHSTPTNGGTNTVNVARPDPDTLRQ
TQGPSYRQIIDLSDLNRSIYVGTLGQSGNPFGDHVSDQQRLWAAGEYLPMSTDAQDWGRTTTLTLTPQR

Sequences:

>Translated_789_residues
MRRLVRVGRGVLWVLLLVLLLALGAVVWLKETSRPQVSGTLTLPGLAGPVSVTRDAWGVPHIRAQASDEDAMFALGFVHA
QDRAWQMDFQRRVAQGRLAEVLGEAALPQDRFLRTWGFYRAAQSALPALSEQARRMVRAYTAGVNAGFAQGRLAPEFRIL
GYTPEPWTDVDSIAWSKLMAYDLGGNADDEILGTQVVRRLGEAKLNEVLPPYPPQAPTILSREELGLQAQAPHHRRVATV
LPAATLRALQAQLEAARALGLERLPGKGSNDWVIAGSRTASGKPILADDPHLALSSPMLWYLADVQGPRLRAIGATIPGL
PGIVIGRNDRVAWGVTNVNPDVQDLYIEPDGAKLTARTEVIKVKGQPDVHLTVRESEHGPIISDVGAGAVGPRVALKWTA
LQPGDTTLEAFLGLNYARNWPDFVAALKRYVAPSQNFVYADVDGNIGYYAPGRVPIRRGWDGSLPVPGDGQHEWSGFIPF
AQLPHTFNPADGLVVTANNKVVPEGYPFNLGNIRNWAEPYRAERITALLTQKPRELTVDDVKRVQLDTVSLVWRDLKPFL
LATRPDGDLSRQALEQLRGWNGDERIDVVPPTIFEAWLAELQQMAQDELGDGTRLSSLAVLNQLRANGQLCRNERDETSR
PQDCAGEMQASLKRAVDRLAARLGPNPAGWTYGKVHTVASNHRAFGGVKALGWLFNHSTPTNGGTNTVNVARPDPDTLRQ
TQGPSYRQIIDLSDLNRSIYVGTLGQSGNPFGDHVSDQQRLWAAGEYLPMSTDAQDWGRTTTLTLTPQR
>Mature_789_residues
MRRLVRVGRGVLWVLLLVLLLALGAVVWLKETSRPQVSGTLTLPGLAGPVSVTRDAWGVPHIRAQASDEDAMFALGFVHA
QDRAWQMDFQRRVAQGRLAEVLGEAALPQDRFLRTWGFYRAAQSALPALSEQARRMVRAYTAGVNAGFAQGRLAPEFRIL
GYTPEPWTDVDSIAWSKLMAYDLGGNADDEILGTQVVRRLGEAKLNEVLPPYPPQAPTILSREELGLQAQAPHHRRVATV
LPAATLRALQAQLEAARALGLERLPGKGSNDWVIAGSRTASGKPILADDPHLALSSPMLWYLADVQGPRLRAIGATIPGL
PGIVIGRNDRVAWGVTNVNPDVQDLYIEPDGAKLTARTEVIKVKGQPDVHLTVRESEHGPIISDVGAGAVGPRVALKWTA
LQPGDTTLEAFLGLNYARNWPDFVAALKRYVAPSQNFVYADVDGNIGYYAPGRVPIRRGWDGSLPVPGDGQHEWSGFIPF
AQLPHTFNPADGLVVTANNKVVPEGYPFNLGNIRNWAEPYRAERITALLTQKPRELTVDDVKRVQLDTVSLVWRDLKPFL
LATRPDGDLSRQALEQLRGWNGDERIDVVPPTIFEAWLAELQQMAQDELGDGTRLSSLAVLNQLRANGQLCRNERDETSR
PQDCAGEMQASLKRAVDRLAARLGPNPAGWTYGKVHTVASNHRAFGGVKALGWLFNHSTPTNGGTNTVNVARPDPDTLRQ
TQGPSYRQIIDLSDLNRSIYVGTLGQSGNPFGDHVSDQQRLWAAGEYLPMSTDAQDWGRTTTLTLTPQR

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 86440; Mature: 86440

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLVRVGRGVLWVLLLVLLLALGAVVWLKETSRPQVSGTLTLPGLAGPVSVTRDAWGVP
CCHHHHHCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECCCCCCCCEECCCCCCCC
HIRAQASDEDAMFALGFVHAQDRAWQMDFQRRVAQGRLAEVLGEAALPQDRFLRTWGFYR
CEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AAQSALPALSEQARRMVRAYTAGVNAGFAQGRLAPEFRILGYTPEPWTDVDSIAWSKLMA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHE
YDLGGNADDEILGTQVVRRLGEAKLNEVLPPYPPQAPTILSREELGLQAQAPHHRRVATV
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHCCCCCCCCCHHHHHHH
LPAATLRALQAQLEAARALGLERLPGKGSNDWVIAGSRTASGKPILADDPHLALSSPMLW
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEECCCCCCCCCEECCCCCCCCCCCEEE
YLADVQGPRLRAIGATIPGLPGIVIGRNDRVAWGVTNVNPDVQDLYIEPDGAKLTARTEV
EEECCCCCCEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCEEEEEEEE
IKVKGQPDVHLTVRESEHGPIISDVGAGAVGPRVALKWTALQPGDTTLEAFLGLNYARNW
EEECCCCCEEEEEEECCCCCEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCC
PDFVAALKRYVAPSQNFVYADVDGNIGYYAPGRVPIRRGWDGSLPVPGDGQHEWSGFIPF
HHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCH
AQLPHTFNPADGLVVTANNKVVPEGYPFNLGNIRNWAEPYRAERITALLTQKPRELTVDD
HHCCCCCCCCCCEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
VKRVQLDTVSLVWRDLKPFLLATRPDGDLSRQALEQLRGWNGDERIDVVPPTIFEAWLAE
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
LQQMAQDELGDGTRLSSLAVLNQLRANGQLCRNERDETSRPQDCAGEMQASLKRAVDRLA
HHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ARLGPNPAGWTYGKVHTVASNHRAFGGVKALGWLFNHSTPTNGGTNTVNVARPDPDTLRQ
HHHCCCCCCCCCCEEEEEECCCCHHCCHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHH
TQGPSYRQIIDLSDLNRSIYVGTLGQSGNPFGDHVSDQQRLWAAGEYLPMSTDAQDWGRT
CCCCCHHEEEEHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHCCCE
TTLTLTPQR
EEEEECCCC
>Mature Secondary Structure
MRRLVRVGRGVLWVLLLVLLLALGAVVWLKETSRPQVSGTLTLPGLAGPVSVTRDAWGVP
CCHHHHHCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECCCCCCCCEECCCCCCCC
HIRAQASDEDAMFALGFVHAQDRAWQMDFQRRVAQGRLAEVLGEAALPQDRFLRTWGFYR
CEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AAQSALPALSEQARRMVRAYTAGVNAGFAQGRLAPEFRILGYTPEPWTDVDSIAWSKLMA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHE
YDLGGNADDEILGTQVVRRLGEAKLNEVLPPYPPQAPTILSREELGLQAQAPHHRRVATV
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHHHCCCCCCCCCHHHHHHH
LPAATLRALQAQLEAARALGLERLPGKGSNDWVIAGSRTASGKPILADDPHLALSSPMLW
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEECCCCCCCCCEECCCCCCCCCCCEEE
YLADVQGPRLRAIGATIPGLPGIVIGRNDRVAWGVTNVNPDVQDLYIEPDGAKLTARTEV
EEECCCCCCEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCCCEEEEEEEE
IKVKGQPDVHLTVRESEHGPIISDVGAGAVGPRVALKWTALQPGDTTLEAFLGLNYARNW
EEECCCCCEEEEEEECCCCCEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCC
PDFVAALKRYVAPSQNFVYADVDGNIGYYAPGRVPIRRGWDGSLPVPGDGQHEWSGFIPF
HHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCH
AQLPHTFNPADGLVVTANNKVVPEGYPFNLGNIRNWAEPYRAERITALLTQKPRELTVDD
HHCCCCCCCCCCEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
VKRVQLDTVSLVWRDLKPFLLATRPDGDLSRQALEQLRGWNGDERIDVVPPTIFEAWLAE
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHH
LQQMAQDELGDGTRLSSLAVLNQLRANGQLCRNERDETSRPQDCAGEMQASLKRAVDRLA
HHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ARLGPNPAGWTYGKVHTVASNHRAFGGVKALGWLFNHSTPTNGGTNTVNVARPDPDTLRQ
HHHCCCCCCCCCCEEEEEECCCCHHCCHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHH
TQGPSYRQIIDLSDLNRSIYVGTLGQSGNPFGDHVSDQQRLWAAGEYLPMSTDAQDWGRT
CCCCCHHEEEEHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHCCCE
TTLTLTPQR
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]