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The map label for this gene is glcK [H]

Identifier: 94984350

GI number: 94984350

Start: 229150

End: 230112

Strand: Reverse

Name: glcK [H]

Synonym: Dgeo_0242

Alternate gene names: 94984350

Gene position: 230112-229150 (Counterclockwise)

Preceding gene: 94984351

Following gene: 94984349

Centisome position: 9.33

GC content: 69.26

Gene sequence:

>963_bases
ATGGGGCGCGGGAATTGGAAGCGCTCCCGCGAAGTAGAAGAGGGAGGCAGAAGAGTGACGGAACTAGCGCAGCAGGTCAG
CATCGGCATCGACGTGGGCGGCACCAAGATCGCCAGCGGGATTCTGCGCGGCGGCGAGTTGCAAGAGCGCCACGTGCAGC
CCACCCCCAGCAGTGGCTGGGAAGCGGTGCTGAACGCCATCGCGGCACGGGTGCGCGAGTTGCAGGCCCGACATCCGGAT
GTGGTGCAGGTCGGCGTGGGCGTGCCGGGGCCACTCAACGCTGACCGCACCCGCGTGAAGTTTGCGCCCAACATCTATGG
CTTTACAGATGTGCCGCTGGTAGACGGCCTGGAAGAGCGCTTGGGCGTGCGGGTGGTGCTGGAAAACGACGCCAAGGCCG
CTGCCCTCGCCGAAGCGCACCTGGGGGCGGCACGTGGCACAGGCAGCAGCGTGTATGTGACCGTCAGCACGGGGATCGGC
GCGGGGATCGTGCTGAATGGGCGCATCTGGCGCGGTCGGCACGGGATCGCCGGGGAACTCGGGCACGTGACCGTGATGCC
GGGCGGGCCGGTCAGCGGGGCGGGCCTCGACGGGGCGCTCGAAGCGGTGGCGAGCGGCACCGCCATCGCCCGCGATGCGA
GCTACGCCCTGAACCGTGGGGTGTCCACCGCCGAGGCCTTTGCCTTGGCTGCGCAGGGCCAACCCGCCGCCCGCCGCATC
GTGGCGCAGGCCCTCAAGCACATCGGGGTTGCCCTGGCCGACCTCCAAAAGCTCCTCGATCCCGAAGTAATCGTGATCGG
AGGTGGCGTGGCGAGCGTCGGGGAGCTGTTTTTCCAGGGCGTCCGCGCTGCCGCCGAGGAATATGCCGCTCCCTTCGCGC
CGGTCACGATTCTGCCCGCACAGCTCGGCACGGACGCCGGGGTAATTGGAGCGGCCCTTGCCGCGCAGCAGGAGGCCGCA
TGA

Upstream 100 bases:

>100_bases
CCGGAGGTGCAGCTGCGCGAGGCGCTCGCACTCCTCCGGGGAGATGGAGAAGACACGACATTTCCTGGCTGATGCGGCCA
GGCGAAAACATGGAGTGCGG

Downstream 100 bases:

>100_bases
GCCGTCCAGCAACCGAACGCCGCCAGGTGGCCCTGATCGCACATGACCGCAAGAAGCTCGAACTGGCCCTCTTTGCCTTA
GGCCACCGCGAGGTGCTGGG

Product: ROK domain-containing protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MGRGNWKRSREVEEGGRRVTELAQQVSIGIDVGGTKIASGILRGGELQERHVQPTPSSGWEAVLNAIAARVRELQARHPD
VVQVGVGVPGPLNADRTRVKFAPNIYGFTDVPLVDGLEERLGVRVVLENDAKAAALAEAHLGAARGTGSSVYVTVSTGIG
AGIVLNGRIWRGRHGIAGELGHVTVMPGGPVSGAGLDGALEAVASGTAIARDASYALNRGVSTAEAFALAAQGQPAARRI
VAQALKHIGVALADLQKLLDPEVIVIGGGVASVGELFFQGVRAAAEEYAAPFAPVTILPAQLGTDAGVIGAALAAQQEAA

Sequences:

>Translated_320_residues
MGRGNWKRSREVEEGGRRVTELAQQVSIGIDVGGTKIASGILRGGELQERHVQPTPSSGWEAVLNAIAARVRELQARHPD
VVQVGVGVPGPLNADRTRVKFAPNIYGFTDVPLVDGLEERLGVRVVLENDAKAAALAEAHLGAARGTGSSVYVTVSTGIG
AGIVLNGRIWRGRHGIAGELGHVTVMPGGPVSGAGLDGALEAVASGTAIARDASYALNRGVSTAEAFALAAQGQPAARRI
VAQALKHIGVALADLQKLLDPEVIVIGGGVASVGELFFQGVRAAAEEYAAPFAPVTILPAQLGTDAGVIGAALAAQQEAA
>Mature_319_residues
GRGNWKRSREVEEGGRRVTELAQQVSIGIDVGGTKIASGILRGGELQERHVQPTPSSGWEAVLNAIAARVRELQARHPDV
VQVGVGVPGPLNADRTRVKFAPNIYGFTDVPLVDGLEERLGVRVVLENDAKAAALAEAHLGAARGTGSSVYVTVSTGIGA
GIVLNGRIWRGRHGIAGELGHVTVMPGGPVSGAGLDGALEAVASGTAIARDASYALNRGVSTAEAFALAAQGQPAARRIV
AQALKHIGVALADLQKLLDPEVIVIGGGVASVGELFFQGVRAAAEEYAAPFAPVTILPAQLGTDAGVIGAALAAQQEAA

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=27.1375464684015, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=27.1375464684015, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI190014632, Length=269, Percent_Identity=27.1375464684015, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=27.1375464684015, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786891, Length=298, Percent_Identity=30.5369127516779, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787363, Length=261, Percent_Identity=32.183908045977, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081733, Length=306, Percent_Identity=32.0261437908497, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082230, Length=269, Percent_Identity=34.5724907063197, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787878, Length=266, Percent_Identity=25.9398496240602, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082127, Length=260, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790522, Length=318, Percent_Identity=25.4716981132075, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32689; Mature: 32557

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRGNWKRSREVEEGGRRVTELAQQVSIGIDVGGTKIASGILRGGELQERHVQPTPSSGW
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCH
EAVLNAIAARVRELQARHPDVVQVGVGVPGPLNADRTRVKFAPNIYGFTDVPLVDGLEER
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHCHHHH
LGVRVVLENDAKAAALAEAHLGAARGTGSSVYVTVSTGIGAGIVLNGRIWRGRHGIAGEL
CCEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCEEEECCCCCCCCC
GHVTVMPGGPVSGAGLDGALEAVASGTAIARDASYALNRGVSTAEAFALAAQGQPAARRI
CEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHH
VAQALKHIGVALADLQKLLDPEVIVIGGGVASVGELFFQGVRAAAEEYAAPFAPVTILPA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
QLGTDAGVIGAALAAQQEAA
HCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRGNWKRSREVEEGGRRVTELAQQVSIGIDVGGTKIASGILRGGELQERHVQPTPSSGW
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCH
EAVLNAIAARVRELQARHPDVVQVGVGVPGPLNADRTRVKFAPNIYGFTDVPLVDGLEER
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHCHHHH
LGVRVVLENDAKAAALAEAHLGAARGTGSSVYVTVSTGIGAGIVLNGRIWRGRHGIAGEL
CCEEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCEEEECCCCCCCCC
GHVTVMPGGPVSGAGLDGALEAVASGTAIARDASYALNRGVSTAEAFALAAQGQPAARRI
CEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHH
VAQALKHIGVALADLQKLLDPEVIVIGGGVASVGELFFQGVRAAAEEYAAPFAPVTILPA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHH
QLGTDAGVIGAALAAQQEAA
HCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]