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The map label for this gene is allB

Identifier: 94972077

GI number: 94972077

Start: 443684

End: 445033

Strand: Direct

Name: allB

Synonym: Dgeo_2609

Alternate gene names: 94972077

Gene position: 443684-445033 (Clockwise)

Preceding gene: 94972078

Following gene: 94972076

Centisome position: 77.28

GC content: 72.15

Gene sequence:

>1350_bases
ATGTACGACCTGCTGGTGCGCGGCGGACAACTGGTGCGGGAGGGCGGCGTGGAGCAGGCCGACCTGGGCGTGGTGGAGGA
GCGCATCGTGGAGATCGCCCCCGAGCTGATGGGGGATGCCCGTGAGGAGCTGGACGCCCGCGGCCTGCACGTCTTTCCCG
GCGCGGTGGATATCCACGTGCATTTCAACGAGCCGGGCCGCACGGACTGGGAGGGCATCCGCACCGGCAGCCGGGCGCTG
GTGGCGGGTGGCGGGACCGTCTTTGCCGATATGCCGCTCAACAGCACGCCGCCCGTGCTCGACCGCACCACCTTCGAGGC
CAAGCAGCAGGCGGCGGAACGCGAGTCCTACGCGGACTTCGCCCTGTGGGGCGGCCTCACGCCCCGCAACCTCGACCGCC
TGCCCGAGCTGGCCGAGGCGGGCGCGGTGGGCTTCAAGGCCTTCATGAGCCACAGCGGCCTGGAGGAGTTCGAGTCCCCC
GACGACTTCACCCTGTACGAGGGGATGCTCCAGGCACGCGACCTGGGTCTGATCGTGGCCCTGCATGCGGAGAGTGACGC
CATCACGCGCGGCCTGTCCACCCGGATTCGCCGTGAGGGCGGCACGGGCGTGCGCGACTACCTGCGCAGCCGCCCCGCGA
TCGCCGAGGTGGAGGCCGTGAACCGCGCTCTGCTGCTCGCCGAGGAGACGGGGGCAAAACTGCACCTCGTCCACCTCTCC
ACCGGGCGGGCCGTCACCCTGGCCGCCGAGGCCCGCGCGCGCGGCGTGGATGTGAGCATCGAAACCTGCCCGCACTACCT
CTGCTTCACCGGCGAGGACATGGAGCGCCTGGGCGCGGTGCTGAAGTGCGCGCCGCCCCTGCGGGACGCCTCGGAAGTGG
ACGCGCTGTGGCAGGCCATCCGCGCGGGCCACATCGACACCATCGGCTCGGACCACTCCCCCAGCACGCTGGACCTCAAG
GAACGCGCCGACTTCTTCGAGGTGTGGGGCGGCATCGCGGGCGTGCAGTCCACCCTCACCGTCCTGCTCACGGAGGGCCG
GGAGCGCGGTCTCTCCTTGCCCGACATCGCGCGCCTGAGCGCCCGCACGCCCGCGGGGCACTTCGGCCTCGCCGGCAAGG
GCCGCCTGGAACCCGGAGCGGACGCCGACCTGGTGCTGGTCGACCTGGACCGCGAGTGGGTCCACACCCCCGAAGACCTG
CACACCCGCTGGAAGTTCAGCCCCTACCTGGGCCGCACCTTCCGCGGCCGGGTCGTGCAGACGCGGCTGCGCGGTCAGAC
GGTATACGCCGAGGGCCGCTTCCCCCACCCGCCCCAGGGCCGCTTCCTGCGTCCCGCCCCCGCGTCTTAG

Upstream 100 bases:

>100_bases
ACCACCCCGACGAGGCCGTGCGGGAAGAGGACGTGGAGGCGGCCCTGCGCGTGGGCACCCGCTTTCTGCGGCAGCTCGCC
GAGCGGGAGGAGGCACGCTG

Downstream 100 bases:

>100_bases
GAGGAAACCGCTTGAACCGCCAACCCAGCCTGCAACAGCTCGGCCAGACCCGCAGCGTGGTGAGTCAGGAATACGCGCTG
CTGACGCCCGAAACCTTTAT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MYDLLVRGGQLVREGGVEQADLGVVEERIVEIAPELMGDAREELDARGLHVFPGAVDIHVHFNEPGRTDWEGIRTGSRAL
VAGGGTVFADMPLNSTPPVLDRTTFEAKQQAAERESYADFALWGGLTPRNLDRLPELAEAGAVGFKAFMSHSGLEEFESP
DDFTLYEGMLQARDLGLIVALHAESDAITRGLSTRIRREGGTGVRDYLRSRPAIAEVEAVNRALLLAEETGAKLHLVHLS
TGRAVTLAAEARARGVDVSIETCPHYLCFTGEDMERLGAVLKCAPPLRDASEVDALWQAIRAGHIDTIGSDHSPSTLDLK
ERADFFEVWGGIAGVQSTLTVLLTEGRERGLSLPDIARLSARTPAGHFGLAGKGRLEPGADADLVLVDLDREWVHTPEDL
HTRWKFSPYLGRTFRGRVVQTRLRGQTVYAEGRFPHPPQGRFLRPAPAS

Sequences:

>Translated_449_residues
MYDLLVRGGQLVREGGVEQADLGVVEERIVEIAPELMGDAREELDARGLHVFPGAVDIHVHFNEPGRTDWEGIRTGSRAL
VAGGGTVFADMPLNSTPPVLDRTTFEAKQQAAERESYADFALWGGLTPRNLDRLPELAEAGAVGFKAFMSHSGLEEFESP
DDFTLYEGMLQARDLGLIVALHAESDAITRGLSTRIRREGGTGVRDYLRSRPAIAEVEAVNRALLLAEETGAKLHLVHLS
TGRAVTLAAEARARGVDVSIETCPHYLCFTGEDMERLGAVLKCAPPLRDASEVDALWQAIRAGHIDTIGSDHSPSTLDLK
ERADFFEVWGGIAGVQSTLTVLLTEGRERGLSLPDIARLSARTPAGHFGLAGKGRLEPGADADLVLVDLDREWVHTPEDL
HTRWKFSPYLGRTFRGRVVQTRLRGQTVYAEGRFPHPPQGRFLRPAPAS
>Mature_449_residues
MYDLLVRGGQLVREGGVEQADLGVVEERIVEIAPELMGDAREELDARGLHVFPGAVDIHVHFNEPGRTDWEGIRTGSRAL
VAGGGTVFADMPLNSTPPVLDRTTFEAKQQAAERESYADFALWGGLTPRNLDRLPELAEAGAVGFKAFMSHSGLEEFESP
DDFTLYEGMLQARDLGLIVALHAESDAITRGLSTRIRREGGTGVRDYLRSRPAIAEVEAVNRALLLAEETGAKLHLVHLS
TGRAVTLAAEARARGVDVSIETCPHYLCFTGEDMERLGAVLKCAPPLRDASEVDALWQAIRAGHIDTIGSDHSPSTLDLK
ERADFFEVWGGIAGVQSTLTVLLTEGRERGLSLPDIARLSARTPAGHFGLAGKGRLEPGADADLVLVDLDREWVHTPEDL
HTRWKFSPYLGRTFRGRVVQTRLRGQTVYAEGRFPHPPQGRFLRPAPAS

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily

Homologues:

Organism=Homo sapiens, GI18105007, Length=396, Percent_Identity=28.2828282828283, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI4503379, Length=468, Percent_Identity=25.4273504273504, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI19923821, Length=453, Percent_Identity=28.0353200883002, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI4503375, Length=457, Percent_Identity=27.3522975929978, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4503051, Length=459, Percent_Identity=24.400871459695, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI62422571, Length=459, Percent_Identity=24.400871459695, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI4503377, Length=444, Percent_Identity=24.7747747747748, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI190194363, Length=459, Percent_Identity=25.4901960784314, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786722, Length=448, Percent_Identity=40.625, Blast_Score=346, Evalue=1e-96,
Organism=Escherichia coli, GI87082175, Length=462, Percent_Identity=31.8181818181818, Blast_Score=194, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI193204318, Length=407, Percent_Identity=28.2555282555283, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17539558, Length=466, Percent_Identity=26.6094420600858, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71989490, Length=464, Percent_Identity=26.9396551724138, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI86575075, Length=463, Percent_Identity=24.622030237581, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322218, Length=389, Percent_Identity=38.3033419023136, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI18859883, Length=421, Percent_Identity=35.8669833729216, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24642586, Length=408, Percent_Identity=30.1470588235294, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI221377917, Length=458, Percent_Identity=26.2008733624454, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17137462, Length=452, Percent_Identity=25.6637168141593, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24644287, Length=308, Percent_Identity=28.2467532467532, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24644289, Length=238, Percent_Identity=27.7310924369748, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALLB_DEIGD (Q1J391)

Other databases:

- EMBL:   CP000358
- RefSeq:   YP_594117.1
- ProteinModelPortal:   Q1J391
- SMR:   Q1J391
- STRING:   Q1J391
- GeneID:   4073840
- GenomeReviews:   CP000358_GR
- KEGG:   dge:Dgeo_2609
- NMPDR:   fig|68909.1.peg.21
- eggNOG:   COG0044
- HOGENOM:   HBG724623
- OMA:   ICHISSP
- PhylomeDB:   Q1J391
- ProtClustDB:   PRK06189
- BioCyc:   DGEO319795:DGEO_2609-MONOMER
- HAMAP:   MF_01645
- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059
- TIGRFAMs:   TIGR03178
- TIGRFAMs:   TIGR00857

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.5

Molecular weight: Translated: 48999; Mature: 48999

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00482 DIHYDROOROTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLLVRGGQLVREGGVEQADLGVVEERIVEIAPELMGDAREELDARGLHVFPGAVDIHV
CCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEE
HFNEPGRTDWEGIRTGSRALVAGGGTVFADMPLNSTPPVLDRTTFEAKQQAAERESYADF
EECCCCCCCHHHHCCCCEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
ALWGGLTPRNLDRLPELAEAGAVGFKAFMSHSGLEEFESPDDFTLYEGMLQARDLGLIVA
CEECCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCEEEEE
LHAESDAITRGLSTRIRREGGTGVRDYLRSRPAIAEVEAVNRALLLAEETGAKLHLVHLS
EECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHEEEEEECCCCEEEEEEEC
TGRAVTLAAEARARGVDVSIETCPHYLCFTGEDMERLGAVLKCAPPLRDASEVDALWQAI
CCCEEEEEEHHHHCCCEEEHHCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
RAGHIDTIGSDHSPSTLDLKERADFFEVWGGIAGVQSTLTVLLTEGRERGLSLPDIARLS
HCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCCCCHHHHHH
ARTPAGHFGLAGKGRLEPGADADLVLVDLDREWVHTPEDLHTRWKFSPYLGRTFRGRVVQ
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCCHHHHHCEECCHHHCCCCCCHHHH
TRLRGQTVYAEGRFPHPPQGRFLRPAPAS
HHHCCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYDLLVRGGQLVREGGVEQADLGVVEERIVEIAPELMGDAREELDARGLHVFPGAVDIHV
CCCEEECCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEE
HFNEPGRTDWEGIRTGSRALVAGGGTVFADMPLNSTPPVLDRTTFEAKQQAAERESYADF
EECCCCCCCHHHHCCCCEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
ALWGGLTPRNLDRLPELAEAGAVGFKAFMSHSGLEEFESPDDFTLYEGMLQARDLGLIVA
CEECCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCEEEEE
LHAESDAITRGLSTRIRREGGTGVRDYLRSRPAIAEVEAVNRALLLAEETGAKLHLVHLS
EECCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHEEEEEECCCCEEEEEEEC
TGRAVTLAAEARARGVDVSIETCPHYLCFTGEDMERLGAVLKCAPPLRDASEVDALWQAI
CCCEEEEEEHHHHCCCEEEHHCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
RAGHIDTIGSDHSPSTLDLKERADFFEVWGGIAGVQSTLTVLLTEGRERGLSLPDIARLS
HCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCCCCHHHHHH
ARTPAGHFGLAGKGRLEPGADADLVLVDLDREWVHTPEDLHTRWKFSPYLGRTFRGRVVQ
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHCCCCHHHHHCEECCHHHCCCCCCHHHH
TRLRGQTVYAEGRFPHPPQGRFLRPAPAS
HHHCCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA