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The map label for this gene is actP1 [H]

Identifier: 94972021

GI number: 94972021

Start: 497141

End: 499657

Strand: Direct

Name: actP1 [H]

Synonym: Dgeo_2553

Alternate gene names: 94972021

Gene position: 497141-499657 (Clockwise)

Preceding gene: 94972024

Following gene: 94972020

Centisome position: 86.59

GC content: 66.94

Gene sequence:

>2517_bases
ATGAGCAAAACGGTGGAACTTGGTGTTCAGGGCATGACCTGCGCCAGTTGCGTGGGCCGGGTCGAGCGGGGCCTGAAAAA
AGTCGAGGGAGTCGAGAGCGCTGTGGTCAACCTCGCCACCGAACGCGCGACGGTGGCCTACGACCCGGAAAAGACCAGCC
CGCAGGCACTGCTGGACAAGGTGAAGGACGTTGGCTACGAACCCATCGTCGGCCACATGGAGCTGGGCGTGCAGGGCATG
ACCTGCGCGAGCTGCGTTGGCCGCGTGGAGCGGGCGCTGAAGAAAGTGGAAGGAGTGCTGGACGCCAGTGTGAACCTCGC
CACCGAGCGTGCCACGGTCACCTACCTCCCCTCCGGCGTCAGTCCCGGGCAACTGAAGGCTGCCGTCCGGGAGGCCGGGT
ACGACGTGCTGGAAGAACAGGCTGGCGTCAGCCGCGAGGACCAGGAGCGCGAGGCGCGCGAGCGCGAAGTCAACCATCTG
CGCCGTCAGGTGCAGTTCAGCGCCGTCTTCGCCATTCCCCTGCTCCTGATCGCGATGGTGCCGATGCTGGTCCCAGCCGT
GAATGACTGGCTGATGACCACCTTCGGTCACGGCGTGATGACCACCCTCAACTGGGTGATGCTGGCGCTGGCGCTGCCCA
TCCAGTTCGGTCCCGGGCTGCGCTTCTACCGCCTGGGCTGGAAGAGCCTGAAGAACAGGTCCCCCGACATGAACGCGCTG
GTGATGATCGGCACCACGGCGGCGTTCCTGTACTCGCTGGTCGCCACGGTGGCGCCCGGCATCTTCCCAGAGGGCACGGC
CCACGTGTATTACGAGGCTTCGGGCGTCGTGATCACCCTGATCCTGCTCGGCAAGTATTTTGAAGCCATCGCCAAGGGCC
GCAGCAGCGAGGCGATGAAGAAGCTGCTCAGCCTGCAAGCCAAGACCGCGCGCGTCGTGCGGAACGGGCAGGAACTCGAA
CTGCCTACGGATGAAGTGCTGGTAGGTGACCTGATCTCCGTCCGCCCCGGCGAGAAGATCCCGGTGGACGGTGAGGTCGT
GCAGGGTGCCAGCTTCGTGGACGAGAGCATGATTACCGGCGAGCCGGTTCCGGTCAGCAAGCAGCCCGGTGCACCTGTGG
TCGGCGGCACCATCAACCAGAACGGTGCCCTGACCTTCCGCGCCACCCGCATCGGGGCAGATACGGCGCTCGCGCAGATC
ATCAAATTGGTCGAGACGGCGCAGGGCAGCAAGCCGCCTATCCAGGGCCTCGCGGACCGGGTGGTCGCGGTGTTCGTCCC
GGTCGTGCTGGGCATTGCGGCCCTGACCTTCCTGCTGTGGCTGATCCTCGGCGGGCAGACCGCGCTCTCCTTCGCCCTGA
TCACGACCGTCGCGGTGCTGATCATCGCCTGCCCCTGCGCGATGGGCCTGGCGACGCCCACCAGCATCATGGTGGGCACT
GGCAAGGCCGCCGAGCTGGGCGTGCTGTTCAAGGGCGGCGGTGCCCTGGAGGGCCTCCAGGACGTGCGGGTGGTGGCGGT
GGACAAGACCGGCACCCTCACGAAAGGCAAGCCGGAACTGACCGACCTGGTAACCGCCCCCCGCTTTGACCGCGCGGAAG
TGCTGCAACTGGTCGCGGCGGCGGAAGAGCAGAGCGAACACCCGATTGCCCGCGCCATCGTGGACGCGGCGAGGAAGGAA
GGAATAGCTGACCTGAAACCCGAGTCCTTTGAAGCGGTGCCCGGCTACGGGCTGGAAGCGCGGGTGGACGGACACCTCGT
GCAGGTGGGCGCGGACCGGTACATGACGCGGCTGGGCCTGGATGTGAATGTCTTCGCGGCCCAGGCCGAACGCCTGGGTG
ATGAGGGCAAGAGCCCGTTGTATGCCGCCGTGGACGGGCAACTCGCCGCCGTGATCGCGGTGGCCGACCCCATCAAGAAA
GGGAGCCAGGAAGCCGTGAATGCCCTGCACCACATGGGCCTCAAGGTGGCGATCATCACCGGGGACAATGCCCGTACGGC
GAGCGCCATCGCCCGCCAGCTCGGCATCGACGAGGTGCTGGCTGAGGTGCTGCCCAGCGGCAAGAGTGAAGCGGTGAAAG
AACTCCAGGCGAAAGGCCAGAAAGTCGCCTTCGTGGGAGACGGCATCAACGACGCTCCGGCGCTGGCCCAGGCCGATGTC
GGCCTCGCCATCGGTACCGGGACCGACGTGGCGGTGGAGACCGCCGACGTGATCCTGATGTCGGGCGACCTGCGGGGCGT
GCCGAACGCCTTCGCGCTCAGCCGCGCCACCTTGCGGAACATCCGGCTCAACCTGTTCTGGGCCTTCGCCTACAACATCG
TCCTGATTCCGGTCGCGGCGGGCGTCCTGTACCCGGCCTTCGGTATCCTTCTCAGCCCGGTGCTCGCTGCCGCCGCCATG
GGCTTTTCCAGCGTCTTCGTGCTCAGCAATGCCCTGCGGCTGCGCGGCTTCCGCCCGCCGGTTCGTCCGGAGGGGGTCTC
CACCGGCGCCCCCTCCACCACTCCGGCCCGGGCCTGA

Upstream 100 bases:

>100_bases
TTCTGGTCTATCCTCCGTAAACAACGCGATGGAGGGTTGTGTATTCCCGGGAACTGGCATATTCTTTCTCTGTACCCCCC
GGAGGGGGATAGGAGAGAGA

Downstream 100 bases:

>100_bases
CCCGTGTTCAGAAGGAAGGTGCGCCCGTGACCACCCGTTCCTCCGCTCGCCCTCCCGCTCCGCTCACTGCGTCCACGGCG
ACCTTCGACTGGGCGGTGGT

Product: heavy metal translocating P-type ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 838; Mature: 837

Protein sequence:

>838_residues
MSKTVELGVQGMTCASCVGRVERGLKKVEGVESAVVNLATERATVAYDPEKTSPQALLDKVKDVGYEPIVGHMELGVQGM
TCASCVGRVERALKKVEGVLDASVNLATERATVTYLPSGVSPGQLKAAVREAGYDVLEEQAGVSREDQEREAREREVNHL
RRQVQFSAVFAIPLLLIAMVPMLVPAVNDWLMTTFGHGVMTTLNWVMLALALPIQFGPGLRFYRLGWKSLKNRSPDMNAL
VMIGTTAAFLYSLVATVAPGIFPEGTAHVYYEASGVVITLILLGKYFEAIAKGRSSEAMKKLLSLQAKTARVVRNGQELE
LPTDEVLVGDLISVRPGEKIPVDGEVVQGASFVDESMITGEPVPVSKQPGAPVVGGTINQNGALTFRATRIGADTALAQI
IKLVETAQGSKPPIQGLADRVVAVFVPVVLGIAALTFLLWLILGGQTALSFALITTVAVLIIACPCAMGLATPTSIMVGT
GKAAELGVLFKGGGALEGLQDVRVVAVDKTGTLTKGKPELTDLVTAPRFDRAEVLQLVAAAEEQSEHPIARAIVDAARKE
GIADLKPESFEAVPGYGLEARVDGHLVQVGADRYMTRLGLDVNVFAAQAERLGDEGKSPLYAAVDGQLAAVIAVADPIKK
GSQEAVNALHHMGLKVAIITGDNARTASAIARQLGIDEVLAEVLPSGKSEAVKELQAKGQKVAFVGDGINDAPALAQADV
GLAIGTGTDVAVETADVILMSGDLRGVPNAFALSRATLRNIRLNLFWAFAYNIVLIPVAAGVLYPAFGILLSPVLAAAAM
GFSSVFVLSNALRLRGFRPPVRPEGVSTGAPSTTPARA

Sequences:

>Translated_838_residues
MSKTVELGVQGMTCASCVGRVERGLKKVEGVESAVVNLATERATVAYDPEKTSPQALLDKVKDVGYEPIVGHMELGVQGM
TCASCVGRVERALKKVEGVLDASVNLATERATVTYLPSGVSPGQLKAAVREAGYDVLEEQAGVSREDQEREAREREVNHL
RRQVQFSAVFAIPLLLIAMVPMLVPAVNDWLMTTFGHGVMTTLNWVMLALALPIQFGPGLRFYRLGWKSLKNRSPDMNAL
VMIGTTAAFLYSLVATVAPGIFPEGTAHVYYEASGVVITLILLGKYFEAIAKGRSSEAMKKLLSLQAKTARVVRNGQELE
LPTDEVLVGDLISVRPGEKIPVDGEVVQGASFVDESMITGEPVPVSKQPGAPVVGGTINQNGALTFRATRIGADTALAQI
IKLVETAQGSKPPIQGLADRVVAVFVPVVLGIAALTFLLWLILGGQTALSFALITTVAVLIIACPCAMGLATPTSIMVGT
GKAAELGVLFKGGGALEGLQDVRVVAVDKTGTLTKGKPELTDLVTAPRFDRAEVLQLVAAAEEQSEHPIARAIVDAARKE
GIADLKPESFEAVPGYGLEARVDGHLVQVGADRYMTRLGLDVNVFAAQAERLGDEGKSPLYAAVDGQLAAVIAVADPIKK
GSQEAVNALHHMGLKVAIITGDNARTASAIARQLGIDEVLAEVLPSGKSEAVKELQAKGQKVAFVGDGINDAPALAQADV
GLAIGTGTDVAVETADVILMSGDLRGVPNAFALSRATLRNIRLNLFWAFAYNIVLIPVAAGVLYPAFGILLSPVLAAAAM
GFSSVFVLSNALRLRGFRPPVRPEGVSTGAPSTTPARA
>Mature_837_residues
SKTVELGVQGMTCASCVGRVERGLKKVEGVESAVVNLATERATVAYDPEKTSPQALLDKVKDVGYEPIVGHMELGVQGMT
CASCVGRVERALKKVEGVLDASVNLATERATVTYLPSGVSPGQLKAAVREAGYDVLEEQAGVSREDQEREAREREVNHLR
RQVQFSAVFAIPLLLIAMVPMLVPAVNDWLMTTFGHGVMTTLNWVMLALALPIQFGPGLRFYRLGWKSLKNRSPDMNALV
MIGTTAAFLYSLVATVAPGIFPEGTAHVYYEASGVVITLILLGKYFEAIAKGRSSEAMKKLLSLQAKTARVVRNGQELEL
PTDEVLVGDLISVRPGEKIPVDGEVVQGASFVDESMITGEPVPVSKQPGAPVVGGTINQNGALTFRATRIGADTALAQII
KLVETAQGSKPPIQGLADRVVAVFVPVVLGIAALTFLLWLILGGQTALSFALITTVAVLIIACPCAMGLATPTSIMVGTG
KAAELGVLFKGGGALEGLQDVRVVAVDKTGTLTKGKPELTDLVTAPRFDRAEVLQLVAAAEEQSEHPIARAIVDAARKEG
IADLKPESFEAVPGYGLEARVDGHLVQVGADRYMTRLGLDVNVFAAQAERLGDEGKSPLYAAVDGQLAAVIAVADPIKKG
SQEAVNALHHMGLKVAIITGDNARTASAIARQLGIDEVLAEVLPSGKSEAVKELQAKGQKVAFVGDGINDAPALAQADVG
LAIGTGTDVAVETADVILMSGDLRGVPNAFALSRATLRNIRLNLFWAFAYNIVLIPVAAGVLYPAFGILLSPVLAAAAMG
FSSVFVLSNALRLRGFRPPVRPEGVSTGAPSTTPARA

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=869, Percent_Identity=39.5857307249712, Blast_Score=578, Evalue=1e-165,
Organism=Homo sapiens, GI115529486, Length=920, Percent_Identity=37.5, Blast_Score=578, Evalue=1e-165,
Organism=Homo sapiens, GI55743073, Length=554, Percent_Identity=42.5992779783394, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI48762685, Length=219, Percent_Identity=31.9634703196347, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI48762691, Length=219, Percent_Identity=31.9634703196347, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI48762689, Length=219, Percent_Identity=31.9634703196347, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI48762687, Length=219, Percent_Identity=31.9634703196347, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI118498343, Length=192, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI10835220, Length=238, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI27886529, Length=238, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI237681109, Length=297, Percent_Identity=26.5993265993266, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI21361181, Length=297, Percent_Identity=26.5993265993266, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI237681111, Length=297, Percent_Identity=26.5993265993266, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI28373109, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI28373105, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI28373113, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI28373103, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI209413709, Length=218, Percent_Identity=28.8990825688073, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI28373115, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI28373111, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI4502285, Length=218, Percent_Identity=28.8990825688073, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI28373107, Length=191, Percent_Identity=27.7486910994764, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI24638454, Length=218, Percent_Identity=28.8990825688073, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI22748667, Length=256, Percent_Identity=26.5625, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI4502271, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI51944966, Length=263, Percent_Identity=26.2357414448669, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI153946397, Length=246, Percent_Identity=26.0162601626016, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI83700225, Length=259, Percent_Identity=26.6409266409266, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI297374799, Length=262, Percent_Identity=25.9541984732824, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1786691, Length=857, Percent_Identity=41.3068844807468, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI1789879, Length=754, Percent_Identity=32.0954907161804, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1786914, Length=534, Percent_Identity=31.4606741573034, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI2367363, Length=593, Percent_Identity=26.6441821247892, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17556548, Length=914, Percent_Identity=35.8862144420131, Blast_Score=479, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17554158, Length=221, Percent_Identity=28.0542986425339, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988506, Length=221, Percent_Identity=28.0542986425339, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210130, Length=221, Percent_Identity=28.0542986425339, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557486, Length=219, Percent_Identity=29.6803652968037, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32566766, Length=211, Percent_Identity=28.9099526066351, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203356, Length=219, Percent_Identity=29.2237442922374, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17557770, Length=211, Percent_Identity=28.9099526066351, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203354, Length=219, Percent_Identity=29.2237442922374, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997262, Length=292, Percent_Identity=25.3424657534247, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71997275, Length=292, Percent_Identity=25.3424657534247, Blast_Score=83, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71997269, Length=292, Percent_Identity=25.3424657534247, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17559224, Length=260, Percent_Identity=26.5384615384615, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=108, Percent_Identity=36.1111111111111, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=890, Percent_Identity=35.6179775280899, Blast_Score=489, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6319772, Length=673, Percent_Identity=31.3521545319465, Blast_Score=313, Evalue=7e-86,
Organism=Saccharomyces cerevisiae, GI6321430, Length=257, Percent_Identity=29.9610894941634, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325221, Length=254, Percent_Identity=29.1338582677165, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321432, Length=188, Percent_Identity=35.1063829787234, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321271, Length=195, Percent_Identity=29.7435897435897, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320244, Length=301, Percent_Identity=26.2458471760797, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320243, Length=301, Percent_Identity=26.2458471760797, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320245, Length=338, Percent_Identity=25.4437869822485, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221329854, Length=631, Percent_Identity=35.9746434231379, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24668704, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668708, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281366617, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24668696, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI161085803, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24762455, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24762453, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24762447, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24762457, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24762449, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24762445, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24762451, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17136664, Length=234, Percent_Identity=29.0598290598291, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24648576, Length=311, Percent_Identity=25.7234726688103, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45553437, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45553441, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648580, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648578, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281362164, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45553435, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45553439, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648582, Length=311, Percent_Identity=25.7234726688103, Blast_Score=77, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR006122
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 88082; Mature: 87951

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTVELGVQGMTCASCVGRVERGLKKVEGVESAVVNLATERATVAYDPEKTSPQALLDK
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHH
VKDVGYEPIVGHMELGVQGMTCASCVGRVERALKKVEGVLDASVNLATERATVTYLPSGV
HHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCC
SPGQLKAAVREAGYDVLEEQAGVSREDQEREAREREVNHLRRQVQFSAVFAIPLLLIAMV
CCHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMLVPAVNDWLMTTFGHGVMTTLNWVMLALALPIQFGPGLRFYRLGWKSLKNRSPDMNAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHCCCCCCCCEE
VMIGTTAAFLYSLVATVAPGIFPEGTAHVYYEASGVVITLILLGKYFEAIAKGRSSEAMK
EEECHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHH
KLLSLQAKTARVVRNGQELELPTDEVLVGDLISVRPGEKIPVDGEVVQGASFVDESMITG
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCC
EPVPVSKQPGAPVVGGTINQNGALTFRATRIGADTALAQIIKLVETAQGSKPPIQGLADR
CCCCCCCCCCCCEECCEECCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VVAVFVPVVLGIAALTFLLWLILGGQTALSFALITTVAVLIIACPCAMGLATPTSIMVGT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GKAAELGVLFKGGGALEGLQDVRVVAVDKTGTLTKGKPELTDLVTAPRFDRAEVLQLVAA
CCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHH
AEEQSEHPIARAIVDAARKEGIADLKPESFEAVPGYGLEARVDGHLVQVGADRYMTRLGL
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECHHHHHHHHCC
DVNVFAAQAERLGDEGKSPLYAAVDGQLAAVIAVADPIKKGSQEAVNALHHMGLKVAIIT
CHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEHHHHCCCHHHHHHHHHHCCEEEEEEE
GDNARTASAIARQLGIDEVLAEVLPSGKSEAVKELQAKGQKVAFVGDGINDAPALAQADV
CCCCHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCC
GLAIGTGTDVAVETADVILMSGDLRGVPNAFALSRATLRNIRLNLFWAFAYNIVLIPVAA
CEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHH
GVLYPAFGILLSPVLAAAAMGFSSVFVLSNALRLRGFRPPVRPEGVSTGAPSTTPARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKTVELGVQGMTCASCVGRVERGLKKVEGVESAVVNLATERATVAYDPEKTSPQALLDK
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHH
VKDVGYEPIVGHMELGVQGMTCASCVGRVERALKKVEGVLDASVNLATERATVTYLPSGV
HHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEECCCCC
SPGQLKAAVREAGYDVLEEQAGVSREDQEREAREREVNHLRRQVQFSAVFAIPLLLIAMV
CCHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMLVPAVNDWLMTTFGHGVMTTLNWVMLALALPIQFGPGLRFYRLGWKSLKNRSPDMNAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHCCCCCCCCEE
VMIGTTAAFLYSLVATVAPGIFPEGTAHVYYEASGVVITLILLGKYFEAIAKGRSSEAMK
EEECHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHH
KLLSLQAKTARVVRNGQELELPTDEVLVGDLISVRPGEKIPVDGEVVQGASFVDESMITG
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCC
EPVPVSKQPGAPVVGGTINQNGALTFRATRIGADTALAQIIKLVETAQGSKPPIQGLADR
CCCCCCCCCCCCEECCEECCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VVAVFVPVVLGIAALTFLLWLILGGQTALSFALITTVAVLIIACPCAMGLATPTSIMVGT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GKAAELGVLFKGGGALEGLQDVRVVAVDKTGTLTKGKPELTDLVTAPRFDRAEVLQLVAA
CCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHH
AEEQSEHPIARAIVDAARKEGIADLKPESFEAVPGYGLEARVDGHLVQVGADRYMTRLGL
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCEEEEECHHHHHHHHCC
DVNVFAAQAERLGDEGKSPLYAAVDGQLAAVIAVADPIKKGSQEAVNALHHMGLKVAIIT
CHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEHHHHCCCHHHHHHHHHHCCEEEEEEE
GDNARTASAIARQLGIDEVLAEVLPSGKSEAVKELQAKGQKVAFVGDGINDAPALAQADV
CCCCHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCC
GLAIGTGTDVAVETADVILMSGDLRGVPNAFALSRATLRNIRLNLFWAFAYNIVLIPVAA
CEEEECCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHH
GVLYPAFGILLSPVLAAAAMGFSSVFVLSNALRLRGFRPPVRPEGVSTGAPSTTPARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]