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The map label for this gene is murQ

Identifier: 94971975

GI number: 94971975

Start: 543379

End: 544296

Strand: Direct

Name: murQ

Synonym: Dgeo_2507

Alternate gene names: 94971975

Gene position: 543379-544296 (Clockwise)

Preceding gene: 94971976

Following gene: 94971974

Centisome position: 94.64

GC content: 72.33

Gene sequence:

>918_bases
ATGACGACGCCCCCTTCCTCTCCCCTTTCCGACCCGCGCCGCACTGAGGGCGTCCATCCCACCCACACCGACCTCGACCG
GCTGGACCCCCTGGCGCTGGTCCAAGTGTTCACCGACGACCAGCGCGCGGCGGTGGAGGCTGTCCGCGCCGCCGTACCCG
CCCTCGCGCGGGCGGTGGAGGCCGCACTCCCCCGCCTGGAACGGGGCGGGCGGCTGGTGTATGTGGGCGCGGGCACCAGC
GGACGCCTGGCGGTCCTGGACGCGACCGAGCTCACGCCGACCTTCTCTTGGCCGCCGGAACGAGCGGTGCCGCTGATCGC
CGGAGGCGAGCGGGCCATTCGGCAGGCGGTGGAGGGCGCGGAGGATGACGCGGAAGCGGGCGCCGCAGACGTGCGCGCGG
CGGGCACCGGCCCTCAGGACGTGCTGATCGCGCTGGCAGCGAGCGGCACCACCCCCTACGTGCTGGGCGCGGTGAGGGCG
GCGCGGGCTCTGGGGGCCCTGACTATCGGCCTCGCCAACAACCCCGGCACACCGCTGCTGGCTGCTGCCGAATGTCCTAT
CCTGCTGGACACTGGGCCGGAGGTGATCAGCGGCAGCACACGCCTGAAGGCTGGGACCGCGCAGAAGATCGCGCTGAATA
CCTTGTCCAGCGCCTTGATGGTGCGGTTGGGCAAAGTGTACGGCAACCTGATGGTGGACGTGAAGGTCAGCAACGCCAAA
CTCGAAACACGCGCCCTGCGCCTCACCTGCCACGCCACCGGCGCCAGCGAGGCCGAAGCCCGCGCCGCGCTGGCGCAGGC
AGGCGGTCGCGTGAAAACCGCACTGGTGATGCTGCGCCTGGGCCTCAGTGCCCCCGAGGCCGAGGTCCGACTCCAGGCAG
CGGGCGGGCACGCGCGGGTGGCCCTGGGGGAAGGATGA

Upstream 100 bases:

>100_bases
CGCAGGGCTGGGCGAACACGCTCCCCCGAACGACCGGTGCCCGTCACGCAGTCAGCGCCGGAAAATGGCTCCTTCCCCCC
TCTCTCCCGGAAACCCTCGC

Downstream 100 bases:

>100_bases
CACGTAACGGCGTGACCGGAAGGAGGATCATTCCCCCGCGCACTCGCGAGCTGCTCGCGGAGGCGGTGGAGCGCAAGGGC
CTGTGCGGCGCGGCGTTGGG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTTPPSSPLSDPRRTEGVHPTHTDLDRLDPLALVQVFTDDQRAAVEAVRAAVPALARAVEAALPRLERGGRLVYVGAGTS
GRLAVLDATELTPTFSWPPERAVPLIAGGERAIRQAVEGAEDDAEAGAADVRAAGTGPQDVLIALAASGTTPYVLGAVRA
ARALGALTIGLANNPGTPLLAAAECPILLDTGPEVISGSTRLKAGTAQKIALNTLSSALMVRLGKVYGNLMVDVKVSNAK
LETRALRLTCHATGASEAEARAALAQAGGRVKTALVMLRLGLSAPEAEVRLQAAGGHARVALGEG

Sequences:

>Translated_305_residues
MTTPPSSPLSDPRRTEGVHPTHTDLDRLDPLALVQVFTDDQRAAVEAVRAAVPALARAVEAALPRLERGGRLVYVGAGTS
GRLAVLDATELTPTFSWPPERAVPLIAGGERAIRQAVEGAEDDAEAGAADVRAAGTGPQDVLIALAASGTTPYVLGAVRA
ARALGALTIGLANNPGTPLLAAAECPILLDTGPEVISGSTRLKAGTAQKIALNTLSSALMVRLGKVYGNLMVDVKVSNAK
LETRALRLTCHATGASEAEARAALAQAGGRVKTALVMLRLGLSAPEAEVRLQAAGGHARVALGEG
>Mature_304_residues
TTPPSSPLSDPRRTEGVHPTHTDLDRLDPLALVQVFTDDQRAAVEAVRAAVPALARAVEAALPRLERGGRLVYVGAGTSG
RLAVLDATELTPTFSWPPERAVPLIAGGERAIRQAVEGAEDDAEAGAADVRAAGTGPQDVLIALAASGTTPYVLGAVRAA
RALGALTIGLANNPGTPLLAAAECPILLDTGPEVISGSTRLKAGTAQKIALNTLSSALMVRLGKVYGNLMVDVKVSNAKL
ETRALRLTCHATGASEAEARAALAQAGGRVKTALVMLRLGLSAPEAEVRLQAAGGHARVALGEG

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=288, Percent_Identity=45.1388888888889, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_DEIGD (Q1J3J3)

Other databases:

- EMBL:   CP000358
- RefSeq:   YP_594015.1
- ProteinModelPortal:   Q1J3J3
- SMR:   Q1J3J3
- STRING:   Q1J3J3
- GeneID:   4073738
- GenomeReviews:   CP000358_GR
- KEGG:   dge:Dgeo_2507
- NMPDR:   fig|68909.1.peg.79
- eggNOG:   COG2103
- HOGENOM:   HBG703490
- OMA:   HLLTEQI
- PhylomeDB:   Q1J3J3
- ProtClustDB:   PRK05441
- BioCyc:   DGEO319795:DGEO_2507-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31149; Mature: 31018

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 90-90 ACT_SITE 121-121

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPSSPLSDPRRTEGVHPTHTDLDRLDPLALVQVFTDDQRAAVEAVRAAVPALARAVE
CCCCCCCCCCCCHHCCCCCCCCCCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
AALPRLERGGRLVYVGAGTSGRLAVLDATELTPTFSWPPERAVPLIAGGERAIRQAVEGA
HHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCC
EDDAEAGAADVRAAGTGPQDVLIALAASGTTPYVLGAVRAARALGALTIGLANNPGTPLL
CCCHHCCCCCEEECCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCEE
AAAECPILLDTGPEVISGSTRLKAGTAQKIALNTLSSALMVRLGKVYGNLMVDVKVSNAK
EECCCCEEEECCCHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCE
LETRALRLTCHATGASEAEARAALAQAGGRVKTALVMLRLGLSAPEAEVRLQAAGGHARV
EEEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEE
ALGEG
EECCC
>Mature Secondary Structure 
TTPPSSPLSDPRRTEGVHPTHTDLDRLDPLALVQVFTDDQRAAVEAVRAAVPALARAVE
CCCCCCCCCCCHHCCCCCCCCCCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
AALPRLERGGRLVYVGAGTSGRLAVLDATELTPTFSWPPERAVPLIAGGERAIRQAVEGA
HHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCC
EDDAEAGAADVRAAGTGPQDVLIALAASGTTPYVLGAVRAARALGALTIGLANNPGTPLL
CCCHHCCCCCEEECCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCEE
AAAECPILLDTGPEVISGSTRLKAGTAQKIALNTLSSALMVRLGKVYGNLMVDVKVSNAK
EECCCCEEEECCCHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCE
LETRALRLTCHATGASEAEARAALAQAGGRVKTALVMLRLGLSAPEAEVRLQAAGGHARV
EEEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEE
ALGEG
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA