| Definition | Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence. |
|---|---|
| Accession | NC_008010 |
| Length | 574,127 |
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The map label for this gene is gno [H]
Identifier: 94971871
GI number: 94971871
Start: 85630
End: 86406
Strand: Direct
Name: gno [H]
Synonym: Dgeo_2403
Alternate gene names: 94971871
Gene position: 85630-86406 (Clockwise)
Preceding gene: 94971872
Following gene: 94971870
Centisome position: 14.91
GC content: 64.74
Gene sequence:
>777_bases ATGGCACTCAAGGATTTGTTTGACCTGACCGGCAAAATCGCCCTGATCACCGGAGGCTCGCGCGGCCTCGGGCTGCAGAT CGCGGAGGGGTTGGGCGAGTACGGCGCAACCGTCGTCCTGACTGCGCGCAAGCAGAACGAGCTGGACGCGGCGCAGGCGC ATCTTGCAGGTCTGGGCATCACCGCGCACGTCTACCCGAACGATCTTTCGCAGTTCGACACGATCGAGCCGCTGGTGGAA CGGATCATGGCGGAGGTTGGCCCGATTCACATCCTGGTCAACAACGCGGGGGCCACCTGGGGCGCTCCCGCCGAGGAACA TCCTTTCGAGGCCTGGCTCAAGGTGATCAACCTCAACGTGAATGCGATGTTCTTGCTCACCCAAGCGGTCGGGCGGCGCT GCATGATTCCGGCCCGCGCGGGGCGCATCATCAACGTCGCCTCAGTCGCGGGCCTCAAGGGCAACAGCCCGCGCATGATG GGCACCCTCGCCTACAACACCGCCAAGGGTGCGGACGTGAACTTCACCCGCGCGCTCGCCGCCGAGTGGGCCAAGTACGG CATCACCGTGAACGCCATCTGCCCCGGCTACTTCCCCACCAAGATGACGAAAGGCACCCTCGCCTATGCGGAGGAGACCA TCCTCGCCCACACGCCCCTGGGCCGCTTGGGCGGTCCCGAAGACCTCAAAGGTCTCGCTCTGCTGCTCGCCAGCGACGCT TCGGCCTATATCACCGGGCAGAACATTGCGGTGGACGGCGGGGTGACGGCAATTTAA
Upstream 100 bases:
>100_bases CTGACGTTCAGAATTGACGCGCACGTACATTTCTCCTTATGGTGGGCGGTGAAGGTTCAAGAGGCTGGCACCGCGTCCCC TACCCCCTGGAGGCATCCTG
Downstream 100 bases:
>100_bases AGGGTGAGGGGCGTTCTGACCCCCTACGGCGAATTCTGCCCGAAAGGAGCACCATGACCCTCACTTCTCTTGAAGACCTC CGCAGCCGCACCGGCCAGGA
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 258; Mature: 257
Protein sequence:
>258_residues MALKDLFDLTGKIALITGGSRGLGLQIAEGLGEYGATVVLTARKQNELDAAQAHLAGLGITAHVYPNDLSQFDTIEPLVE RIMAEVGPIHILVNNAGATWGAPAEEHPFEAWLKVINLNVNAMFLLTQAVGRRCMIPARAGRIINVASVAGLKGNSPRMM GTLAYNTAKGADVNFTRALAAEWAKYGITVNAICPGYFPTKMTKGTLAYAEETILAHTPLGRLGGPEDLKGLALLLASDA SAYITGQNIAVDGGVTAI
Sequences:
>Translated_258_residues MALKDLFDLTGKIALITGGSRGLGLQIAEGLGEYGATVVLTARKQNELDAAQAHLAGLGITAHVYPNDLSQFDTIEPLVE RIMAEVGPIHILVNNAGATWGAPAEEHPFEAWLKVINLNVNAMFLLTQAVGRRCMIPARAGRIINVASVAGLKGNSPRMM GTLAYNTAKGADVNFTRALAAEWAKYGITVNAICPGYFPTKMTKGTLAYAEETILAHTPLGRLGGPEDLKGLALLLASDA SAYITGQNIAVDGGVTAI >Mature_257_residues ALKDLFDLTGKIALITGGSRGLGLQIAEGLGEYGATVVLTARKQNELDAAQAHLAGLGITAHVYPNDLSQFDTIEPLVER IMAEVGPIHILVNNAGATWGAPAEEHPFEAWLKVINLNVNAMFLLTQAVGRRCMIPARAGRIINVASVAGLKGNSPRMMG TLAYNTAKGADVNFTRALAAEWAKYGITVNAICPGYFPTKMTKGTLAYAEETILAHTPLGRLGGPEDLKGLALLLASDAS AYITGQNIAVDGGVTAI
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=32.7935222672065, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=33.4630350194552, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=31.3725490196078, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=31.640625, Blast_Score=104, Evalue=8e-23, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.1587301587302, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=29.1338582677165, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=28.8537549407115, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=28.968253968254, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI210032110, Length=201, Percent_Identity=31.3432835820896, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=30.9178743961353, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI33667109, Length=206, Percent_Identity=31.5533980582524, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI142976729, Length=208, Percent_Identity=31.7307692307692, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=204, Percent_Identity=29.9019607843137, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=27.0992366412214, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=29.4871794871795, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI126723191, Length=198, Percent_Identity=32.3232323232323, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI209862901, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI19923983, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI186928839, Length=210, Percent_Identity=31.9047619047619, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI225579078, Length=214, Percent_Identity=28.0373831775701, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=38.0392156862745, Blast_Score=164, Evalue=5e-42, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=40.5622489959839, Blast_Score=161, Evalue=3e-41, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=38, Blast_Score=147, Evalue=7e-37, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=34.3511450381679, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=34.375, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.0204081632653, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.5882352941176, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=31.7269076305221, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=28.6792452830189, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=30.0395256916996, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787526, Length=242, Percent_Identity=28.5123966942149, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=28.3400809716599, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.4591439688716, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=29.5964125560538, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=38.6100386100386, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=31.9838056680162, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=31.8007662835249, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=31.3432835820896, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=30.3370786516854, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=30.4511278195489, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=30.7407407407407, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=31.5985130111524, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=28.7822878228782, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=28.7313432835821, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=29.2490118577075, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=28.9473684210526, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=32.5, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=31.6831683168317, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=29.1828793774319, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=30.0395256916996, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.1954887218045, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.7313432835821, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=30.9701492537313, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=28.7313432835821, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=27.2388059701493, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=28.1954887218045, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=29.6875, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=28.3582089552239, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=27.3809523809524, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=28.7878787878788, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.3787878787879, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508895, Length=202, Percent_Identity=30.1980198019802, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17555612, Length=214, Percent_Identity=30.8411214953271, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538182, Length=264, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17558006, Length=216, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=28.6290322580645, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=33.7254901960784, Blast_Score=131, Evalue=5e-31, Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=32.156862745098, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=30.5882352941176, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=32.9411764705882, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=30.1960784313725, Blast_Score=103, Evalue=8e-23, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=30.5019305019305, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21358495, Length=203, Percent_Identity=32.0197044334975, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI161076371, Length=224, Percent_Identity=30.8035714285714, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI22024069, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI281364892, Length=177, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI19921754, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584752, Length=202, Percent_Identity=30.1980198019802, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28573296, Length=210, Percent_Identity=27.6190476190476, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=27.7992277992278, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24640442, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27080; Mature: 26948
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALKDLFDLTGKIALITGGSRGLGLQIAEGLGEYGATVVLTARKQNELDAAQAHLAGLGI CCHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCE TAHVYPNDLSQFDTIEPLVERIMAEVGPIHILVNNAGATWGAPAEEHPFEAWLKVINLNV EEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCC NAMFLLTQAVGRRCMIPARAGRIINVASVAGLKGNSPRMMGTLAYNTAKGADVNFTRALA CCEEEEEHHHCCEEECCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHHH AEWAKYGITVNAICPGYFPTKMTKGTLAYAEETILAHTPLGRLGGPEDLKGLALLLASDA HHHHHHCEEEEEECCCCCCCCCCCCCHHHHHCEEEEECCCCCCCCCCHHHHEEEEEECCC SAYITGQNIAVDGGVTAI CEEEECCEEEECCCEECC >Mature Secondary Structure ALKDLFDLTGKIALITGGSRGLGLQIAEGLGEYGATVVLTARKQNELDAAQAHLAGLGI CHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCE TAHVYPNDLSQFDTIEPLVERIMAEVGPIHILVNNAGATWGAPAEEHPFEAWLKVINLNV EEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCC NAMFLLTQAVGRRCMIPARAGRIINVASVAGLKGNSPRMMGTLAYNTAKGADVNFTRALA CCEEEEEHHHCCEEECCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHHH AEWAKYGITVNAICPGYFPTKMTKGTLAYAEETILAHTPLGRLGGPEDLKGLALLLASDA HHHHHHCEEEEEECCCCCCCCCCCCCHHHHHCEEEEECCCCCCCCCCHHHHEEEEEECCC SAYITGQNIAVDGGVTAI CEEEECCEEEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]