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The map label for this gene is yngJ [H]

Identifier: 94971867

GI number: 94971867

Start: 88562

End: 89800

Strand: Direct

Name: yngJ [H]

Synonym: Dgeo_2399

Alternate gene names: 94971867

Gene position: 88562-89800 (Clockwise)

Preceding gene: 94971868

Following gene: 94971866

Centisome position: 15.43

GC content: 68.04

Gene sequence:

>1239_bases
ATGACCCTGTTCGACGTTTCGCCGCGCACCCAAGACCTGCACGCGCGCCTCAGCCGCTTCATGGACGAGTACATCTATCC
CAACGAAGCCGAATTTCACCGCCAGGTGAATGAGGGCAACCGCTGGGAACACGTGCAGCTCATCGAGGAACTCAAGCCCA
GGGCGCGGGCGGAGGGCTTGTGGAACCTCTTCCTGCCGCCGGCCTCCGACCCCCAGGGCCGCTTTGGGCCGGGCCTCACC
AATCTGGAATACGCCCCCCTGTGCGAGATGATGGGCCGGGTGTGGTGGGCACCCGAAGTCTTCAACTGCTCGGCCCCTGA
CACCGGCAACATGGAGGTGCTGGCCCGCTACGGCACGCCCGAGCAGCAGCAGCAGTGGCTCGTGCCGCTGCTGAACGGTG
AAATCCGCTCCGCCTTCTCTATGACCGAGCCGGAGGTGGCCAGCAGTGACGCCACGAACATCCAGGCTCGCATTCGGCGC
GACGGCGACGAGTACGTGATCAACGGGCGCAAGTGGTGGACGAGTGGGGCGGGTGATCCCCGGTGCCGAGTCAGCATCTT
CATGGGCAAGACCGACCCAGGGGCCGAGCGCCACCTCCAGCAGTCCATGATCCTGGTGCCGCTGGACACGCCCGGCGTGC
GCGTGGAGCGGATGCTGACCGTCTTCGGTTACGACGACGCCCCGCACGGTCACGCCGAGATGACTTTCGAGAACGTGCGC
GTGCCCGCCGCCAACCTGCTGCTGGGCGAGGGCCGGGGCTTTGAGATCGCACAGGGCCGCCTGGGACCGGGCCGCATCCA
CCACTGCATGCGGCTGATTGGGCAGGCCGAGCGCGCGCTGGAGCTGATGGTGGAACGGGCCTCTCGGCGGGTCGCGTTTG
GCAAGCCCCTCGCCGCGCACCAGCATGTGCGGGAGGCCATCGCGCACAGCCGCATGGAGATCGACCAGGCCCGGCTGCTC
ACCCTCCAGGCTGCCCACATGATGGATACGGTGGGCAACAAGGCGGCGCGTGGGCAGATCGCCGCGATCAAGGTGGTCGC
GCCCAACGTCGCCCTGCGAGTCATCGACCGCGCCATTCAGGTGTTTGGCGGTGCGGGCGTCAGCCAGGATACGCCCCTCG
CCATGGTGTACGCCCAGGCCCGCACCCTGCGTCTCGCGGACGGCCCCGACATCGTGCACATCGAGACGGTGGCGAAGGAG
GAGTTGCGGCGGCAGGGGGTGGATGGGCGGGGGCGCTGA

Upstream 100 bases:

>100_bases
GTGGATGGCAAGGTGTGCGGCTGGCCATCTCGCCGGTGCTGGGCTTCGGCGTGGGCGAGACAGCCACTGTTCGCCCGCCG
CGGTCCGAGGAGGAACCCCT

Downstream 100 bases:

>100_bases
GACTCTTGTGGACAGCAACAAGCGGACCGCCTACGCTGCCGCCTAGGTGTTCTTGCTGCTGAACGGCGCGGCACTGATCG
GACCGGACGACGCCGTGTTT

Product: acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTLFDVSPRTQDLHARLSRFMDEYIYPNEAEFHRQVNEGNRWEHVQLIEELKPRARAEGLWNLFLPPASDPQGRFGPGLT
NLEYAPLCEMMGRVWWAPEVFNCSAPDTGNMEVLARYGTPEQQQQWLVPLLNGEIRSAFSMTEPEVASSDATNIQARIRR
DGDEYVINGRKWWTSGAGDPRCRVSIFMGKTDPGAERHLQQSMILVPLDTPGVRVERMLTVFGYDDAPHGHAEMTFENVR
VPAANLLLGEGRGFEIAQGRLGPGRIHHCMRLIGQAERALELMVERASRRVAFGKPLAAHQHVREAIAHSRMEIDQARLL
TLQAAHMMDTVGNKAARGQIAAIKVVAPNVALRVIDRAIQVFGGAGVSQDTPLAMVYAQARTLRLADGPDIVHIETVAKE
ELRRQGVDGRGR

Sequences:

>Translated_412_residues
MTLFDVSPRTQDLHARLSRFMDEYIYPNEAEFHRQVNEGNRWEHVQLIEELKPRARAEGLWNLFLPPASDPQGRFGPGLT
NLEYAPLCEMMGRVWWAPEVFNCSAPDTGNMEVLARYGTPEQQQQWLVPLLNGEIRSAFSMTEPEVASSDATNIQARIRR
DGDEYVINGRKWWTSGAGDPRCRVSIFMGKTDPGAERHLQQSMILVPLDTPGVRVERMLTVFGYDDAPHGHAEMTFENVR
VPAANLLLGEGRGFEIAQGRLGPGRIHHCMRLIGQAERALELMVERASRRVAFGKPLAAHQHVREAIAHSRMEIDQARLL
TLQAAHMMDTVGNKAARGQIAAIKVVAPNVALRVIDRAIQVFGGAGVSQDTPLAMVYAQARTLRLADGPDIVHIETVAKE
ELRRQGVDGRGR
>Mature_411_residues
TLFDVSPRTQDLHARLSRFMDEYIYPNEAEFHRQVNEGNRWEHVQLIEELKPRARAEGLWNLFLPPASDPQGRFGPGLTN
LEYAPLCEMMGRVWWAPEVFNCSAPDTGNMEVLARYGTPEQQQQWLVPLLNGEIRSAFSMTEPEVASSDATNIQARIRRD
GDEYVINGRKWWTSGAGDPRCRVSIFMGKTDPGAERHLQQSMILVPLDTPGVRVERMLTVFGYDDAPHGHAEMTFENVRV
PAANLLLGEGRGFEIAQGRLGPGRIHHCMRLIGQAERALELMVERASRRVAFGKPLAAHQHVREAIAHSRMEIDQARLLT
LQAAHMMDTVGNKAARGQIAAIKVVAPNVALRVIDRAIQVFGGAGVSQDTPLAMVYAQARTLRLADGPDIVHIETVAKEE
LRRQGVDGRGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=399, Percent_Identity=61.6541353383459, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI48976061, Length=399, Percent_Identity=61.6541353383459, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI38505218, Length=410, Percent_Identity=55.8536585365854, Blast_Score=463, Evalue=1e-130,
Organism=Homo sapiens, GI4557233, Length=400, Percent_Identity=28.5, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI4501859, Length=327, Percent_Identity=29.3577981651376, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI187960098, Length=409, Percent_Identity=26.161369193154, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4557231, Length=409, Percent_Identity=26.161369193154, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=25.1322751322751, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI7656849, Length=276, Percent_Identity=27.8985507246377, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI76496475, Length=413, Percent_Identity=25.90799031477, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557235, Length=418, Percent_Identity=26.0765550239234, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226958412, Length=390, Percent_Identity=24.3589743589744, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=25.5952380952381, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501857, Length=312, Percent_Identity=25.6410256410256, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7669494, Length=262, Percent_Identity=25.5725190839695, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4503943, Length=265, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87081958, Length=313, Percent_Identity=26.1980830670927, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786223, Length=296, Percent_Identity=23.9864864864865, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=358, Percent_Identity=60.3351955307263, Blast_Score=459, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17534899, Length=416, Percent_Identity=26.4423076923077, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17569725, Length=415, Percent_Identity=25.7831325301205, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17570075, Length=412, Percent_Identity=24.0291262135922, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=329, Percent_Identity=26.7477203647416, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17506239, Length=289, Percent_Identity=27.681660899654, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=292, Percent_Identity=26.3698630136986, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=342, Percent_Identity=28.0701754385965, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=279, Percent_Identity=28.673835125448, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=391, Percent_Identity=23.5294117647059, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=399, Percent_Identity=24.812030075188, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=260, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=257, Percent_Identity=27.6264591439689, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=195, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281363737, Length=393, Percent_Identity=28.498727735369, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24646207, Length=358, Percent_Identity=29.0502793296089, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24660351, Length=271, Percent_Identity=30.6273062730627, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21356377, Length=402, Percent_Identity=26.865671641791, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24666513, Length=287, Percent_Identity=29.616724738676, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355753, Length=275, Percent_Identity=25.0909090909091, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19920834, Length=293, Percent_Identity=24.9146757679181, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 46043; Mature: 45912

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFDVSPRTQDLHARLSRFMDEYIYPNEAEFHRQVNEGNRWEHVQLIEELKPRARAEGL
CCEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCHHHHHCCC
WNLFLPPASDPQGRFGPGLTNLEYAPLCEMMGRVWWAPEVFNCSAPDTGNMEVLARYGTP
EEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCCC
EQQQQWLVPLLNGEIRSAFSMTEPEVASSDATNIQARIRRDGDEYVINGRKWWTSGAGDP
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHEEECCCCEEEECCEEEECCCCCCC
RCRVSIFMGKTDPGAERHLQQSMILVPLDTPGVRVERMLTVFGYDDAPHGHAEMTFENVR
CEEEEEEECCCCCCHHHHHHHCEEEEECCCCCCCHHHEEEEECCCCCCCCCCEEEHHHCC
VPAANLLLGEGRGFEIAQGRLGPGRIHHCMRLIGQAERALELMVERASRRVAFGKPLAAH
CCHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QHVREAIAHSRMEIDQARLLTLQAAHMMDTVGNKAARGQIAAIKVVAPNVALRVIDRAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHH
VFGGAGVSQDTPLAMVYAQARTLRLADGPDIVHIETVAKEELRRQGVDGRGR
HHCCCCCCCCCCCEEEEECHHEEEECCCCCEEEEHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLFDVSPRTQDLHARLSRFMDEYIYPNEAEFHRQVNEGNRWEHVQLIEELKPRARAEGL
CEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCHHHHHCCC
WNLFLPPASDPQGRFGPGLTNLEYAPLCEMMGRVWWAPEVFNCSAPDTGNMEVLARYGTP
EEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCCC
EQQQQWLVPLLNGEIRSAFSMTEPEVASSDATNIQARIRRDGDEYVINGRKWWTSGAGDP
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHEEECCCCEEEECCEEEECCCCCCC
RCRVSIFMGKTDPGAERHLQQSMILVPLDTPGVRVERMLTVFGYDDAPHGHAEMTFENVR
CEEEEEEECCCCCCHHHHHHHCEEEEECCCCCCCHHHEEEEECCCCCCCCCCEEEHHHCC
VPAANLLLGEGRGFEIAQGRLGPGRIHHCMRLIGQAERALELMVERASRRVAFGKPLAAH
CCHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QHVREAIAHSRMEIDQARLLTLQAAHMMDTVGNKAARGQIAAIKVVAPNVALRVIDRAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHH
VFGGAGVSQDTPLAMVYAQARTLRLADGPDIVHIETVAKEELRRQGVDGRGR
HHCCCCCCCCCCCEEEEECHHEEEECCCCCEEEEHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]