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The map label for this gene is mocA [H]

Identifier: 94314846

GI number: 94314846

Start: 128254

End: 129279

Strand: Direct

Name: mocA [H]

Synonym: Rmet_5927

Alternate gene names: 94314846

Gene position: 128254-129279 (Clockwise)

Preceding gene: 94314845

Following gene: 94314847

Centisome position: 4.97

GC content: 65.79

Gene sequence:

>1026_bases
ATGCCAGATTTCGCCATGCAATACCGCCGCCTTGGCGCCAGCAACCTGAACGTCTCGACCCTGTGCCTGGGCACGATGAT
GTTCGCCGATCAGACCGACGAGGCCGAGGCCGCCCGCATCGTCGCCAGCGCGCGTGAGCACGGTGTGAACTTTATCGACA
CCGCCGACGTGTACAGCAAGGGGGCATCCGAACAGATGGTAGGACGGTTGCTGGCCGGCAGTCGCCACGACTGGGTGCTG
GCGACCAAGCTCGGTAACGCGATGGGTAGTGGCCCGAACCAGTCGAACTACTCGCGCACGTGGATCATGCGTTCGGTGGA
AGACAGCCTGACCCGTCTGGCCACCGACTACATCGACATCCTGTACCTGCATCGCGATTTCGCCGGCGCCAATCTCGAAG
AGCCCGTGCGTGCGATGGGTGACCTGATCCGGGCCGGCAAGATCCGCTACTGGGCCGTGTCGAATTTCCGGGGCTGGCGC
ATCGCGGAAATCGCCGCGCTGTGCGACCGGCTCGGTGTGCCGCGTCCGGTTGCCTGTCAGCCGTATTACAACCTGCTGAA
CCGGGTGCCCGAAGTCGAGATCCTGCCCGCCTGCCAGCACTTCGGCCTGGGCGTGGTGCCCTACAGCCCGATCGCGCGTG
GTGTCCTGACCGGCAAGTATCTACCCGGCCAGGCACCCGGTGCGGAAACGCGCGCCGGCCGCGCGGACAGGCGCATCATG
GAAACCGAATTCCGCGAGGAATCGCTGGTCATCGCGCAGACGCTCAAGAGCCATGCCGAGGGTCGTGGACTGACGCCGGG
CCAATTCGCCACCGCGTGGGTGCTTGCCAACCCGATCATCAGTTCGGTGATCGCTGGCCCGCGTACGCTGGCGCAATTCG
AGGATTACTTTGGCGCGGTGGCCGCGGCGATCACCCCGGCGGAAGAAGCCATGGTCGACGGCCTGGTGCCGCGCGGACAT
GCGTCGACGCACGGGTACAACGACCCGGGATACCCGTTTGGCGGACGTCCCGTCGCTGCCGCCTAG

Upstream 100 bases:

>100_bases
TTTCGCCGCCGCCCGGCAGACATCTGGCGCCCTGCAAGCTCTACCGCAACGCGGCACAATGCGTGAAGTCCTCCCCGCTC
GTCCTATTCAGGAATCCACC

Downstream 100 bases:

>100_bases
CAGCCACACGTAGCCTCCCGCATCCCCATTCCGGGTGTGATTCCCAAGCTGCCTGTTGCGCCCAGTGCACGAAGGCTGAC
ACCCATGTGCGCCAGCCAAC

Product: aldo/keto oxidoreductase, NADP-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPDFAMQYRRLGASNLNVSTLCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSKGASEQMVGRLLAGSRHDWVL
ATKLGNAMGSGPNQSNYSRTWIMRSVEDSLTRLATDYIDILYLHRDFAGANLEEPVRAMGDLIRAGKIRYWAVSNFRGWR
IAEIAALCDRLGVPRPVACQPYYNLLNRVPEVEILPACQHFGLGVVPYSPIARGVLTGKYLPGQAPGAETRAGRADRRIM
ETEFREESLVIAQTLKSHAEGRGLTPGQFATAWVLANPIISSVIAGPRTLAQFEDYFGAVAAAITPAEEAMVDGLVPRGH
ASTHGYNDPGYPFGGRPVAAA

Sequences:

>Translated_341_residues
MPDFAMQYRRLGASNLNVSTLCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSKGASEQMVGRLLAGSRHDWVL
ATKLGNAMGSGPNQSNYSRTWIMRSVEDSLTRLATDYIDILYLHRDFAGANLEEPVRAMGDLIRAGKIRYWAVSNFRGWR
IAEIAALCDRLGVPRPVACQPYYNLLNRVPEVEILPACQHFGLGVVPYSPIARGVLTGKYLPGQAPGAETRAGRADRRIM
ETEFREESLVIAQTLKSHAEGRGLTPGQFATAWVLANPIISSVIAGPRTLAQFEDYFGAVAAAITPAEEAMVDGLVPRGH
ASTHGYNDPGYPFGGRPVAAA
>Mature_340_residues
PDFAMQYRRLGASNLNVSTLCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSKGASEQMVGRLLAGSRHDWVLA
TKLGNAMGSGPNQSNYSRTWIMRSVEDSLTRLATDYIDILYLHRDFAGANLEEPVRAMGDLIRAGKIRYWAVSNFRGWRI
AEIAALCDRLGVPRPVACQPYYNLLNRVPEVEILPACQHFGLGVVPYSPIARGVLTGKYLPGQAPGAETRAGRADRRIME
TEFREESLVIAQTLKSHAEGRGLTPGQFATAWVLANPIISSVIAGPRTLAQFEDYFGAVAAAITPAEEAMVDGLVPRGHA
STHGYNDPGYPFGGRPVAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=304, Percent_Identity=33.8815789473684, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=33.5504885993485, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI27436966, Length=306, Percent_Identity=33.9869281045752, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=32.0872274143302, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI27436969, Length=306, Percent_Identity=32.0261437908497, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4504825, Length=304, Percent_Identity=31.9078947368421, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI223718702, Length=327, Percent_Identity=29.3577981651376, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI41152114, Length=328, Percent_Identity=28.9634146341463, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41327764, Length=316, Percent_Identity=28.7974683544304, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI223718708, Length=171, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081735, Length=318, Percent_Identity=37.4213836477987, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789199, Length=324, Percent_Identity=33.9506172839506, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=31.1728395061728, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788081, Length=274, Percent_Identity=29.9270072992701, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=26.605504587156, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787674, Length=299, Percent_Identity=22.0735785953177, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=329, Percent_Identity=27.0516717325228, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=26.791277258567, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25.3378378378378, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=322, Percent_Identity=25.776397515528, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=26.2745098039216, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323684, Length=163, Percent_Identity=33.1288343558282, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=29.5964125560538, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45549126, Length=325, Percent_Identity=24.9230769230769, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640980, Length=325, Percent_Identity=24.9230769230769, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646155, Length=292, Percent_Identity=25.6849315068493, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37030; Mature: 36898

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFAMQYRRLGASNLNVSTLCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSK
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECHHHHHC
GASEQMVGRLLAGSRHDWVLATKLGNAMGSGPNQSNYSRTWIMRSVEDSLTRLATDYIDI
CCHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LYLHRDFAGANLEEPVRAMGDLIRAGKIRYWAVSNFRGWRIAEIAALCDRLGVPRPVACQ
HHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
PYYNLLNRVPEVEILPACQHFGLGVVPYSPIARGVLTGKYLPGQAPGAETRAGRADRRIM
HHHHHHHHCCCCEEEHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
ETEFREESLVIAQTLKSHAEGRGLTPGQFATAWVLANPIISSVIAGPRTLAQFEDYFGAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAAITPAEEAMVDGLVPRGHASTHGYNDPGYPFGGRPVAAA
HHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDFAMQYRRLGASNLNVSTLCLGTMMFADQTDEAEAARIVASAREHGVNFIDTADVYSK
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECHHHHHC
GASEQMVGRLLAGSRHDWVLATKLGNAMGSGPNQSNYSRTWIMRSVEDSLTRLATDYIDI
CCHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LYLHRDFAGANLEEPVRAMGDLIRAGKIRYWAVSNFRGWRIAEIAALCDRLGVPRPVACQ
HHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
PYYNLLNRVPEVEILPACQHFGLGVVPYSPIARGVLTGKYLPGQAPGAETRAGRADRRIM
HHHHHHHHCCCCEEEHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
ETEFREESLVIAQTLKSHAEGRGLTPGQFATAWVLANPIISSVIAGPRTLAQFEDYFGAV
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AAAITPAEEAMVDGLVPRGHASTHGYNDPGYPFGGRPVAAA
HHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]