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The map label for this gene is yngJ [H]

Identifier: 94314827

GI number: 94314827

Start: 108283

End: 109440

Strand: Direct

Name: yngJ [H]

Synonym: Rmet_5908

Alternate gene names: 94314827

Gene position: 108283-109440 (Clockwise)

Preceding gene: 94314826

Following gene: 94314828

Centisome position: 4.2

GC content: 63.21

Gene sequence:

>1158_bases
ATGGCCCTCGACGCCGAATCCTTTTCCTTGCTGCGCGCTTCGGTGCAGCGTTTTATCGACGATCGCCTGAAGCCGGCCGA
GGACACGCTCGAAGAGATTGACGATGTGCCGGCCGATATCGTGGCCGACATGAAGGAAATGGGCCTGTTCGGCATCTCGA
TTCCCGAGAGCTATGGTGGCATCGGCCTGTCGATGTCGCAGGAATGCGATGTGGTCTACGACTTGGGCCACACTGCTTTT
GCCTTCCGCTCGGTGTTCGGCACTAACGTGGGTATCGGCTCGCAGGGCATCCTGATGGACGGCACCGAGGAACAGAAGCA
GACCTATCTGCCGAAGATCGCCAGCGGCGAACTGATCATCTCGTTCGCGCTGACCGAGCCGAACGCCGGCTCCGACGCCG
CCTCGCTGCAAACGCGCGCCGACCTCGACGGCGACCACTACGTGATCAACGGTACCAAGCGGTTCATCACCAACGCGCCG
CGCGCGGGGGCGTTCACGCTAATGGCACGCACGGGTGGCCAAGGCGCGTCGGGCATTTCGTCGTTCATCGTGCCGGCCGA
TACCCCGGGCATCTCACTGGGCAAGCCGGACAAGAAGATGGGCCAGCGCGGTACCAAGACGTGCGACGTGGTGCTGGAAA
ACGTGCGCGTGCCGGCCGCCAACATCATCGGCGGCGTTCCGGGCGTGGGTTTCAAGACGGCGATGAAGGTGCTGGACCGT
GGCCGCCTGCACATCTCGGCGCTGGCCTGCGGCATGGCGCACCGGCTGATTACCGACGCCGTGGCGTATGCGAAGGAGCG
CAAGCAGTTCGGCAAGCCGATCGGCGATTTCCAACTGATCCAGGGGATGCTGGCCGACAGCCAGGCCGAACTCTATGCGG
GCCTGTCGATGGTGCGCGATTGCGCACAGCGTTATGATGCGAAGCCGGCTGGCAAGAGCGATCCGGAAGTCAGCATGCTG
GCATCGTGCACGAAGATGTTCTGTACCGAGATGGTGGGCCGCGTAGCGGACCGCGCGGTGCAGATCCACGGTGGTGCGGG
TTATATCGCCGAATACAAGGCCGAGCGCTTCTACCGCGACGTGCGTCTGCTGCGCCTCTATGAAGGCACGACGCAGATCC
AGCAGCTCATCATCGCCAAGCAACTGCTGCGCGACTGA

Upstream 100 bases:

>100_bases
ATACTTTCGGTTCTGTCCAAGTCGCAGTGGATTGTCAAATTCGGTAGTCCGCGTACCATTGTTCGCCTTCGTTATCGCAT
CTGAATCACCGGAGATTGCC

Downstream 100 bases:

>100_bases
GCAAGGCTCAAGAAAGCCGGAACGATCAGGCCAGATGGGCCTGAGGGGATAGGAGACAGGATGAGCAGGTTCCAGGTAAC
GGCCTCGCAAGGGCCGGTCA

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MALDAESFSLLRASVQRFIDDRLKPAEDTLEEIDDVPADIVADMKEMGLFGISIPESYGGIGLSMSQECDVVYDLGHTAF
AFRSVFGTNVGIGSQGILMDGTEEQKQTYLPKIASGELIISFALTEPNAGSDAASLQTRADLDGDHYVINGTKRFITNAP
RAGAFTLMARTGGQGASGISSFIVPADTPGISLGKPDKKMGQRGTKTCDVVLENVRVPAANIIGGVPGVGFKTAMKVLDR
GRLHISALACGMAHRLITDAVAYAKERKQFGKPIGDFQLIQGMLADSQAELYAGLSMVRDCAQRYDAKPAGKSDPEVSML
ASCTKMFCTEMVGRVADRAVQIHGGAGYIAEYKAERFYRDVRLLRLYEGTTQIQQLIIAKQLLRD

Sequences:

>Translated_385_residues
MALDAESFSLLRASVQRFIDDRLKPAEDTLEEIDDVPADIVADMKEMGLFGISIPESYGGIGLSMSQECDVVYDLGHTAF
AFRSVFGTNVGIGSQGILMDGTEEQKQTYLPKIASGELIISFALTEPNAGSDAASLQTRADLDGDHYVINGTKRFITNAP
RAGAFTLMARTGGQGASGISSFIVPADTPGISLGKPDKKMGQRGTKTCDVVLENVRVPAANIIGGVPGVGFKTAMKVLDR
GRLHISALACGMAHRLITDAVAYAKERKQFGKPIGDFQLIQGMLADSQAELYAGLSMVRDCAQRYDAKPAGKSDPEVSML
ASCTKMFCTEMVGRVADRAVQIHGGAGYIAEYKAERFYRDVRLLRLYEGTTQIQQLIIAKQLLRD
>Mature_384_residues
ALDAESFSLLRASVQRFIDDRLKPAEDTLEEIDDVPADIVADMKEMGLFGISIPESYGGIGLSMSQECDVVYDLGHTAFA
FRSVFGTNVGIGSQGILMDGTEEQKQTYLPKIASGELIISFALTEPNAGSDAASLQTRADLDGDHYVINGTKRFITNAPR
AGAFTLMARTGGQGASGISSFIVPADTPGISLGKPDKKMGQRGTKTCDVVLENVRVPAANIIGGVPGVGFKTAMKVLDRG
RLHISALACGMAHRLITDAVAYAKERKQFGKPIGDFQLIQGMLADSQAELYAGLSMVRDCAQRYDAKPAGKSDPEVSMLA
SCTKMFCTEMVGRVADRAVQIHGGAGYIAEYKAERFYRDVRLLRLYEGTTQIQQLIIAKQLLRD

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=381, Percent_Identity=39.8950131233596, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=36, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=36.4102564102564, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=36.4102564102564, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=37.17277486911, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=34.9333333333333, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=34.9333333333333, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=33.5120643431635, Blast_Score=214, Evalue=9e-56,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=31.3157894736842, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI226958414, Length=382, Percent_Identity=31.6753926701571, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=30.3430079155673, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=31.2169312169312, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI7669494, Length=364, Percent_Identity=31.043956043956, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI48976061, Length=396, Percent_Identity=28.7878787878788, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI211971008, Length=396, Percent_Identity=28.7878787878788, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI38505218, Length=395, Percent_Identity=27.8481012658228, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1786223, Length=349, Percent_Identity=28.6532951289398, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=30.0518134715026, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081702, Length=347, Percent_Identity=29.3948126801153, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082384, Length=272, Percent_Identity=26.4705882352941, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=35.0132625994695, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17569725, Length=374, Percent_Identity=36.6310160427808, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=35.9042553191489, Blast_Score=234, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI71985184, Length=373, Percent_Identity=36.9973190348526, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=34.7480106100796, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=34.3915343915344, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=35.054347826087, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=32.258064516129, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=38.86925795053, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71990804, Length=259, Percent_Identity=36.2934362934363, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=38.5281385281385, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17505929, Length=381, Percent_Identity=29.1338582677165, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=28.3819628647215, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17551932, Length=384, Percent_Identity=28.6458333333333, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=33.2089552238806, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=33.1983805668016, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=364, Percent_Identity=28.2967032967033, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=185, Percent_Identity=30.2702702702703, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363737, Length=373, Percent_Identity=36.7292225201072, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI21356377, Length=384, Percent_Identity=35.15625, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24646207, Length=389, Percent_Identity=35.73264781491, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24660351, Length=389, Percent_Identity=33.6760925449871, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666513, Length=378, Percent_Identity=35.4497354497354, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=34.0369393139842, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=29.5514511873351, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24652780, Length=360, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41465; Mature: 41334

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDAESFSLLRASVQRFIDDRLKPAEDTLEEIDDVPADIVADMKEMGLFGISIPESYGG
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCC
IGLSMSQECDVVYDLGHTAFAFRSVFGTNVGIGSQGILMDGTEEQKQTYLPKIASGELII
CCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHCCCCCCCCEEE
SFALTEPNAGSDAASLQTRADLDGDHYVINGTKRFITNAPRAGAFTLMARTGGQGASGIS
EEEECCCCCCCCHHHHHHHCCCCCCEEEECCHHHHHCCCCCCCEEEEEEECCCCCCCCHH
SFIVPADTPGISLGKPDKKMGQRGTKTCDVVLENVRVPAANIIGGVPGVGFKTAMKVLDR
HEEECCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHC
GRLHISALACGMAHRLITDAVAYAKERKQFGKPIGDFQLIQGMLADSQAELYAGLSMVRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
CAQRYDAKPAGKSDPEVSMLASCTKMFCTEMVGRVADRAVQIHGGAGYIAEYKAERFYRD
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHH
VRLLRLYEGTTQIQQLIIAKQLLRD
HHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALDAESFSLLRASVQRFIDDRLKPAEDTLEEIDDVPADIVADMKEMGLFGISIPESYGG
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCEEEEECCCCCCC
IGLSMSQECDVVYDLGHTAFAFRSVFGTNVGIGSQGILMDGTEEQKQTYLPKIASGELII
CCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHCCCCCCCCEEE
SFALTEPNAGSDAASLQTRADLDGDHYVINGTKRFITNAPRAGAFTLMARTGGQGASGIS
EEEECCCCCCCCHHHHHHHCCCCCCEEEECCHHHHHCCCCCCCEEEEEEECCCCCCCCHH
SFIVPADTPGISLGKPDKKMGQRGTKTCDVVLENVRVPAANIIGGVPGVGFKTAMKVLDR
HEEECCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHC
GRLHISALACGMAHRLITDAVAYAKERKQFGKPIGDFQLIQGMLADSQAELYAGLSMVRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
CAQRYDAKPAGKSDPEVSMLASCTKMFCTEMVGRVADRAVQIHGGAGYIAEYKAERFYRD
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHH
VRLLRLYEGTTQIQQLIIAKQLLRD
HHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]