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The map label for this gene is epsA [H]

Identifier: 94314770

GI number: 94314770

Start: 45455

End: 46543

Strand: Reverse

Name: epsA [H]

Synonym: Rmet_5851

Alternate gene names: 94314770

Gene position: 46543-45455 (Counterclockwise)

Preceding gene: 94314772

Following gene: 94314769

Centisome position: 1.8

GC content: 65.56

Gene sequence:

>1089_bases
ATGGCCTGCGCGGCGCTGCTGCTGAGCGCGTGCGCGGTGTCTCCGGGGATGCAGTTCAGCTCCAGTGCGCCGGTCAATGC
GGTGAGCCCGAACGCGATGCCTGATGTCACACCCATCACGCTCGACCTCGTGCACGAACAGCAGGCGCACTCCAAGCCGA
CCAATGCCGGCGTGGAGGACCTGTACGGCACACCAACGCCTTATCGTATCGGCCCTGGCGACATCATCTCGGTCGTGGTC
TGGGACCACCCCGAACTCGTGTTCCCGACGCAGACGTACAGCATCGGCGCGGCCTTCGAGATCCCGACGTCGAGCGGCGG
CTCCAACATGCCTGGCTACGTGGTCAGCCCCGCGGGCGATATCCAGTTTCCGTACGCCGGGGTGATGCGCGTGGCGGGCA
AGACCGCCAACGAAGTGCGCGACGAGATGGCGCGCATCCTGTCGCGCGTGGTGCGTGACCCGCAGATGACCGTGCGCGTG
CTCGGCTTCCGCAGCCAGCGCGTCTACGTGGATGGGGAGGTCAAGACCCCGGGGATGCTGGCCATCGACGATGCGCCAAT
GACACTGGTCGAGGCGCTGAACCGCGCCGGCGGCGTGCTTAACCTGACCGGCGACAACAGCCGCGTCCGTGTCACACGTG
GTGAACGCAGCTGGTACGTCAACATTCCGGCACTGCTGGCCAAGGGCACAGACCCCGCGCGGATTCTGCTGCAATCGGGC
GACATCGTTCGCGTGGAGCAACGCGAAGACAGCAAGATCTTCGTGACAGGCGAGGTGGTTAAGCCCTCGTCGCTGCTGAT
GCGTAACGGCCGCATGACGCTGAACGAAGCGCTGGGCGATGCCGGTGGCGTGAATCCGTCGTCGGCCAACGCCGAACAGA
TCTTCGTGATTCGCCGGGCCACCGACGGCAAGCCGAAGGTGTACCACCTCGACGGCACCTCGCCGGTGGCACTGGCCATC
GCCGAGAGCTTCGAGCTCGAACCCAAGGACGTGGTCTACGTGGATGCGCGTGACCTCGTGCGCTGGAGCCGTGTGATGAC
GCTGCTGATCCAGCCGGTCGTCGGCACGGCCACCATTGTCAAGCCATAA

Upstream 100 bases:

>100_bases
TTTCAACGACTGCGGAGAGGATGCCGTGAAGAGATGCCCTGACCACGCCACCTGCAGGCAGGATGCCGGATCGTTTCATG
CGCTGGGAGCCACGCTTGCC

Downstream 100 bases:

>100_bases
GACATGGAAGTCATGAGAGAGGGAAAGGAAGCCGCATTCATCCGGTCGATCCTCGTGGTGTGTATCGGCAACCGGTGCCG
CAGCCCGATGGCGGCGGCAC

Product: EPS I polysaccharide export outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MACAALLLSACAVSPGMQFSSSAPVNAVSPNAMPDVTPITLDLVHEQQAHSKPTNAGVEDLYGTPTPYRIGPGDIISVVV
WDHPELVFPTQTYSIGAAFEIPTSSGGSNMPGYVVSPAGDIQFPYAGVMRVAGKTANEVRDEMARILSRVVRDPQMTVRV
LGFRSQRVYVDGEVKTPGMLAIDDAPMTLVEALNRAGGVLNLTGDNSRVRVTRGERSWYVNIPALLAKGTDPARILLQSG
DIVRVEQREDSKIFVTGEVVKPSSLLMRNGRMTLNEALGDAGGVNPSSANAEQIFVIRRATDGKPKVYHLDGTSPVALAI
AESFELEPKDVVYVDARDLVRWSRVMTLLIQPVVGTATIVKP

Sequences:

>Translated_362_residues
MACAALLLSACAVSPGMQFSSSAPVNAVSPNAMPDVTPITLDLVHEQQAHSKPTNAGVEDLYGTPTPYRIGPGDIISVVV
WDHPELVFPTQTYSIGAAFEIPTSSGGSNMPGYVVSPAGDIQFPYAGVMRVAGKTANEVRDEMARILSRVVRDPQMTVRV
LGFRSQRVYVDGEVKTPGMLAIDDAPMTLVEALNRAGGVLNLTGDNSRVRVTRGERSWYVNIPALLAKGTDPARILLQSG
DIVRVEQREDSKIFVTGEVVKPSSLLMRNGRMTLNEALGDAGGVNPSSANAEQIFVIRRATDGKPKVYHLDGTSPVALAI
AESFELEPKDVVYVDARDLVRWSRVMTLLIQPVVGTATIVKP
>Mature_361_residues
ACAALLLSACAVSPGMQFSSSAPVNAVSPNAMPDVTPITLDLVHEQQAHSKPTNAGVEDLYGTPTPYRIGPGDIISVVVW
DHPELVFPTQTYSIGAAFEIPTSSGGSNMPGYVVSPAGDIQFPYAGVMRVAGKTANEVRDEMARILSRVVRDPQMTVRVL
GFRSQRVYVDGEVKTPGMLAIDDAPMTLVEALNRAGGVLNLTGDNSRVRVTRGERSWYVNIPALLAKGTDPARILLQSGD
IVRVEQREDSKIFVTGEVVKPSSLLMRNGRMTLNEALGDAGGVNPSSANAEQIFVIRRATDGKPKVYHLDGTSPVALAIA
ESFELEPKDVVYVDARDLVRWSRVMTLLIQPVVGTATIVKP

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=367, Percent_Identity=37.3297002724796, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1788376, Length=371, Percent_Identity=35.0404312668464, Blast_Score=201, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 38836; Mature: 38705

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACAALLLSACAVSPGMQFSSSAPVNAVSPNAMPDVTPITLDLVHEQQAHSKPTNAGVED
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCCHHH
LYGTPTPYRIGPGDIISVVVWDHPELVFPTQTYSIGAAFEIPTSSGGSNMPGYVVSPAGD
HCCCCCCCEECCCCEEEEEEECCCCEEECCCCEECCEEEECCCCCCCCCCCCEEECCCCC
IQFPYAGVMRVAGKTANEVRDEMARILSRVVRDPQMTVRVLGFRSQRVYVDGEVKTPGML
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECCCCCCCCEE
AIDDAPMTLVEALNRAGGVLNLTGDNSRVRVTRGERSWYVNIPALLAKGTDPARILLQSG
EECCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEEECHHHEECCCCCCEEEEECC
DIVRVEQREDSKIFVTGEVVKPSSLLMRNGRMTLNEALGDAGGVNPSSANAEQIFVIRRA
CEEEEEECCCCEEEEEECEECCHHHHHCCCCEEHHHHCCCCCCCCCCCCCCEEEEEEEEC
TDGKPKVYHLDGTSPVALAIAESFELEPKDVVYVDARDLVRWSRVMTLLIQPVVGTATIV
CCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEE
KP
CC
>Mature Secondary Structure 
ACAALLLSACAVSPGMQFSSSAPVNAVSPNAMPDVTPITLDLVHEQQAHSKPTNAGVED
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCCHHH
LYGTPTPYRIGPGDIISVVVWDHPELVFPTQTYSIGAAFEIPTSSGGSNMPGYVVSPAGD
HCCCCCCCEECCCCEEEEEEECCCCEEECCCCEECCEEEECCCCCCCCCCCCEEECCCCC
IQFPYAGVMRVAGKTANEVRDEMARILSRVVRDPQMTVRVLGFRSQRVYVDGEVKTPGML
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECCCCCCCCEE
AIDDAPMTLVEALNRAGGVLNLTGDNSRVRVTRGERSWYVNIPALLAKGTDPARILLQSG
EECCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCEEEEECHHHEECCCCCCEEEEECC
DIVRVEQREDSKIFVTGEVVKPSSLLMRNGRMTLNEALGDAGGVNPSSANAEQIFVIRRA
CEEEEEECCCCEEEEEECEECCHHHHHCCCCEEHHHHCCCCCCCCCCCCCCEEEEEEEEC
TDGKPKVYHLDGTSPVALAIAESFELEPKDVVYVDARDLVRWSRVMTLLIQPVVGTATIV
CCCCCEEEEECCCCCEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEE
KP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]