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The map label for this gene is yngI [H]

Identifier: 94314687

GI number: 94314687

Start: 2526843

End: 2528477

Strand: Direct

Name: yngI [H]

Synonym: Rmet_5768

Alternate gene names: 94314687

Gene position: 2526843-2528477 (Clockwise)

Preceding gene: 94314685

Following gene: 94314690

Centisome position: 97.94

GC content: 67.4

Gene sequence:

>1635_bases
ATGCCGACCGACTACGACACCGGACTGGCCCGCAACCCCGCCAACTACGTTCCGATCACCCCGCTCGACTTCATCGCCCG
CGCGGCCGAGGTCTACGGCGATCGCCTGGCCATCGTGCATGGCACGGTGCGCCAGAACTGGCGCGACACCTACGCGCGCT
GCCGGCGCCTGGCCAGCGCGCTGACCCGCGCGGGCGTGGGCAAGGGCGATACCGTGGCGGCGCTGCTGCCCAACACCCCG
GCGATGGTCGAGGCGCACTTCGGCGTGCCGATGGCCGGTGCGGTGCTGAATGCACTCAACATCCGCCTGGACGCCGCCAA
CCTGGTCTTCATGCTGCGCCACGGCGAAGCCAAGGTGCTGCTGGCGGACACCGAGTTCGCCGATGCCGCCCGTCAGATGG
CGCGCGAGGTGCGTGGACTCAAGGTGATCGCGGTGGAAGACGTGCTCGGGCCCGACGCCGAGCGGTTCGGTGACACCGAT
TACGAGTCCTTCCTGGCCAGCGGCGATCCGGAATTCGACTGGAAGATGCCCGGCGACGAGTGGGACGCCATTGCCCTGAA
CTACACGTCGGGCACTACCGGCGACCCGAAGGGCGTGGTCTATCACCATCGCGGCGCGGCCATGAACGCCATCTCCAACA
TCCTGGAGTGGGACATGGCCAAGCATCCGGTCTACCTGTGGACGCTGCCGATGTTCCACTGCAACGGCTGGTGCTTCCCG
TGGACAGTCGCGGCCCGCGCCGGCGTGAACGTCTGCCTGCGCAAGTTCGAGCCGAAGCTCGTCTTCGACCTGATGCGCGA
CGAAGGTGTGACGCACTACTGCGCCGCGCCGATCGTCCACACCGCGCTGGTCAACGCGCCGCCGTCGTGGCGCGAAGGGC
TGCGCGGGCCGGTGCGCGGCATGGTGGCGGGCGCCCCGCCCCCGGCGGCGGTGCTGGCGCAGATGGAAGCGATGGGTTTC
GACCTGTCGCATGTCTACGGCCTGACCGAGGTCTACGGCCCGGCCGCGGTCTGCGCGGAGCAGGACGCCTGGCACACGGT
GTCGCAGGAAGAACGCGCGGTGCTGAAGGCGCGCCAGGGCGTGCGCTATCACCTGCAGTCCGGCGTCACGGTGCTGGACC
CGGATACGATGCAGCCCGTACCGCGCGACGGCGAGACCATCGGCGAAATCATGTTCCGCGGCAACATCTGCATGAAGGGT
TACCTCAAGAACGACAAGGCCACGCGCGAGGCGTTCGCGGGCGGCTGGTTCCATACGGGCGACCTTGGCGTGTGCATGCC
TGACGGCTACATCAAGATCAAGGACCGCAGCAAGGACATCATCATCTCCGGCGGGGAGAACATTTCCAGCGTCGAGGTGG
AAGACGCGCTCTACCGCCACCCCGCGGTGCTGGCCGCCGCCGTGGTGGCGCAGCCGGATGCCAAGTGGGGCGAGACGCCG
TGCGCGTTCGTCGAACTGAAGGATGGCGCAAGCGTCACGGCCGAAGAACTGATTGCACATTGCCGCACGCTGCTGGCCGG
CTTCAAGGTGCCGAAGGCGGTCTACTTCGGGCCGCTGCCCAAGACCTCTACCGGCAAGATCCAGAAGTTCGAACTGCGCA
AGAAGATGCAGTCGAACGCTGCCATCGACGTCTGA

Upstream 100 bases:

>100_bases
AGATCTGTCATCCGGACGACAGAGTCCGCCGGAGGCGAGATGATAGCTTGCGCCGGATTTCATTCGACGAATCCCCAAGG
ATCACCATAGGAGACACGCC

Downstream 100 bases:

>100_bases
TCGACCGATCGACCAATCGACCAATCGCTTGATGGAAAAAACGCGCGGCGGGTCGCCCCGCCGCGCGTTTTTTATCGACA
TTCCCGCTCAAAACTGTCCG

Product: acyl-CoA synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MPTDYDTGLARNPANYVPITPLDFIARAAEVYGDRLAIVHGTVRQNWRDTYARCRRLASALTRAGVGKGDTVAALLPNTP
AMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEAKVLLADTEFADAARQMAREVRGLKVIAVEDVLGPDAERFGDTD
YESFLASGDPEFDWKMPGDEWDAIALNYTSGTTGDPKGVVYHHRGAAMNAISNILEWDMAKHPVYLWTLPMFHCNGWCFP
WTVAARAGVNVCLRKFEPKLVFDLMRDEGVTHYCAAPIVHTALVNAPPSWREGLRGPVRGMVAGAPPPAAVLAQMEAMGF
DLSHVYGLTEVYGPAAVCAEQDAWHTVSQEERAVLKARQGVRYHLQSGVTVLDPDTMQPVPRDGETIGEIMFRGNICMKG
YLKNDKATREAFAGGWFHTGDLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDAKWGETP
CAFVELKDGASVTAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRKKMQSNAAIDV

Sequences:

>Translated_544_residues
MPTDYDTGLARNPANYVPITPLDFIARAAEVYGDRLAIVHGTVRQNWRDTYARCRRLASALTRAGVGKGDTVAALLPNTP
AMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEAKVLLADTEFADAARQMAREVRGLKVIAVEDVLGPDAERFGDTD
YESFLASGDPEFDWKMPGDEWDAIALNYTSGTTGDPKGVVYHHRGAAMNAISNILEWDMAKHPVYLWTLPMFHCNGWCFP
WTVAARAGVNVCLRKFEPKLVFDLMRDEGVTHYCAAPIVHTALVNAPPSWREGLRGPVRGMVAGAPPPAAVLAQMEAMGF
DLSHVYGLTEVYGPAAVCAEQDAWHTVSQEERAVLKARQGVRYHLQSGVTVLDPDTMQPVPRDGETIGEIMFRGNICMKG
YLKNDKATREAFAGGWFHTGDLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDAKWGETP
CAFVELKDGASVTAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRKKMQSNAAIDV
>Mature_543_residues
PTDYDTGLARNPANYVPITPLDFIARAAEVYGDRLAIVHGTVRQNWRDTYARCRRLASALTRAGVGKGDTVAALLPNTPA
MVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEAKVLLADTEFADAARQMAREVRGLKVIAVEDVLGPDAERFGDTDY
ESFLASGDPEFDWKMPGDEWDAIALNYTSGTTGDPKGVVYHHRGAAMNAISNILEWDMAKHPVYLWTLPMFHCNGWCFPW
TVAARAGVNVCLRKFEPKLVFDLMRDEGVTHYCAAPIVHTALVNAPPSWREGLRGPVRGMVAGAPPPAAVLAQMEAMGFD
LSHVYGLTEVYGPAAVCAEQDAWHTVSQEERAVLKARQGVRYHLQSGVTVLDPDTMQPVPRDGETIGEIMFRGNICMKGY
LKNDKATREAFAGGWFHTGDLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDAKWGETPC
AFVELKDGASVTAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRKKMQSNAAIDV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=535, Percent_Identity=29.1588785046729, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI187761345, Length=550, Percent_Identity=28.3636363636364, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI187761343, Length=550, Percent_Identity=28.3636363636364, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI157311624, Length=516, Percent_Identity=27.3255813953488, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI157311622, Length=516, Percent_Identity=27.3255813953488, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI122937307, Length=511, Percent_Identity=27.3972602739726, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI58082049, Length=511, Percent_Identity=27.0058708414873, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI115511026, Length=561, Percent_Identity=26.5597147950089, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI42544132, Length=517, Percent_Identity=26.8858800773694, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI38505220, Length=515, Percent_Identity=25.4368932038835, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI28416953, Length=130, Percent_Identity=36.1538461538462, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4758332, Length=504, Percent_Identity=22.8174603174603, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI12669909, Length=504, Percent_Identity=22.8174603174603, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI253970489, Length=129, Percent_Identity=37.984496124031, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI8923896, Length=129, Percent_Identity=37.984496124031, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI40807491, Length=230, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI145693145, Length=541, Percent_Identity=30.8687615526802, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI221142682, Length=521, Percent_Identity=27.2552783109405, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788107, Length=562, Percent_Identity=27.4021352313167, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1786810, Length=561, Percent_Identity=26.2032085561497, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71994703, Length=532, Percent_Identity=27.4436090225564, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71994690, Length=532, Percent_Identity=27.4436090225564, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71994694, Length=532, Percent_Identity=27.4436090225564, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17560308, Length=528, Percent_Identity=28.9772727272727, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17558820, Length=505, Percent_Identity=27.7227722772277, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538037, Length=526, Percent_Identity=24.7148288973384, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32563687, Length=522, Percent_Identity=25.6704980842912, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17559526, Length=536, Percent_Identity=25, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17557194, Length=523, Percent_Identity=25.2390057361377, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17531443, Length=511, Percent_Identity=22.7005870841487, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17560140, Length=558, Percent_Identity=24.5519713261649, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71996755, Length=540, Percent_Identity=23.5185185185185, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982997, Length=571, Percent_Identity=25.3940455341506, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71983001, Length=571, Percent_Identity=25.3940455341506, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=600, Percent_Identity=24, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17510401, Length=182, Percent_Identity=32.4175824175824, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319699, Length=489, Percent_Identity=26.7893660531697, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323182, Length=143, Percent_Identity=34.965034965035, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581924, Length=548, Percent_Identity=28.2846715328467, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI18859661, Length=561, Percent_Identity=26.9162210338681, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355181, Length=532, Percent_Identity=25.187969924812, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19922652, Length=539, Percent_Identity=25.0463821892393, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24583465, Length=470, Percent_Identity=24.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24583463, Length=470, Percent_Identity=24.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364798, Length=470, Percent_Identity=24.2553191489362, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648260, Length=495, Percent_Identity=23.4343434343434, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21356947, Length=497, Percent_Identity=22.1327967806841, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281365686, Length=471, Percent_Identity=21.8683651804671, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653035, Length=470, Percent_Identity=22.9787234042553, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20130357, Length=535, Percent_Identity=22.2429906542056, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356441, Length=469, Percent_Identity=20.2558635394456, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648257, Length=481, Percent_Identity=23.9085239085239, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 59338; Mature: 59206

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDYDTGLARNPANYVPITPLDFIARAAEVYGDRLAIVHGTVRQNWRDTYARCRRLASA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH
LTRAGVGKGDTVAALLPNTPAMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEAKVL
HHHCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHEEEECCEEEEEEECCCEEEE
LADTEFADAARQMAREVRGLKVIAVEDVLGPDAERFGDTDYESFLASGDPEFDWKMPGDE
EECCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCCCCHHHHHHCCCCCCCCCCCCCC
WDAIALNYTSGTTGDPKGVVYHHRGAAMNAISNILEWDMAKHPVYLWTLPMFHCNGWCFP
CCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCH
WTVAARAGVNVCLRKFEPKLVFDLMRDEGVTHYCAAPIVHTALVNAPPSWREGLRGPVRG
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHH
MVAGAPPPAAVLAQMEAMGFDLSHVYGLTEVYGPAAVCAEQDAWHTVSQEERAVLKARQG
EECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHCC
VRYHLQSGVTVLDPDTMQPVPRDGETIGEIMFRGNICMKGYLKNDKATREAFAGGWFHTG
CHHHHHCCCEEECCCCCCCCCCCCHHHHHHHEECCEEEEEEECCCHHHHHHHCCCCEEEC
DLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDAKWGETP
CEEEECCCCEEEEECCCCEEEEECCCCCCEEEHHHHHHHCHHHHHHHHHCCCCCCCCCCC
CAFVELKDGASVTAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRKKMQSNA
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCC
AIDV
CCCC
>Mature Secondary Structure 
PTDYDTGLARNPANYVPITPLDFIARAAEVYGDRLAIVHGTVRQNWRDTYARCRRLASA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH
LTRAGVGKGDTVAALLPNTPAMVEAHFGVPMAGAVLNALNIRLDAANLVFMLRHGEAKVL
HHHCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHHHHHHEEEECCEEEEEEECCCEEEE
LADTEFADAARQMAREVRGLKVIAVEDVLGPDAERFGDTDYESFLASGDPEFDWKMPGDE
EECCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCCCCHHHHHHCCCCCCCCCCCCCC
WDAIALNYTSGTTGDPKGVVYHHRGAAMNAISNILEWDMAKHPVYLWTLPMFHCNGWCFP
CCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCH
WTVAARAGVNVCLRKFEPKLVFDLMRDEGVTHYCAAPIVHTALVNAPPSWREGLRGPVRG
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHH
MVAGAPPPAAVLAQMEAMGFDLSHVYGLTEVYGPAAVCAEQDAWHTVSQEERAVLKARQG
EECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHCC
VRYHLQSGVTVLDPDTMQPVPRDGETIGEIMFRGNICMKGYLKNDKATREAFAGGWFHTG
CHHHHHCCCEEECCCCCCCCCCCCHHHHHHHEECCEEEEEEECCCHHHHHHHCCCCEEEC
DLGVCMPDGYIKIKDRSKDIIISGGENISSVEVEDALYRHPAVLAAAVVAQPDAKWGETP
CEEEECCCCEEEEECCCCEEEEECCCCCCEEEHHHHHHHCHHHHHHHHHCCCCCCCCCCC
CAFVELKDGASVTAEELIAHCRTLLAGFKVPKAVYFGPLPKTSTGKIQKFELRKKMQSNA
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCC
AIDV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]